Skip to main content

Quantification of coeliac disease toxic gluten in foodstuffs using a chip system with integrated extraction, fluidics and biosensoric detection step 2 of exploratory award exaw-1999-01542

Objective

The overall objective of the project is the development of a disposable microsystem with integrated optimal extraction and detection for the precise $ accurate quantitation of coeliac disease toxic gluten (CD-toxic gluten sequences of gluten to which coeliac disease sufferers show intorelance) in all types of foodstuffs. A standard universal protocol for extraction of gliadins and glutenins from all food states Enzyme linked assays and biosensors exploiting antibodies, antibody fragments and aptamers will be developed for the detection of CD-toxic gluten in raw, cooked, processed and unprocessed food. Finally, a disposable microsystem with integrated microstructured extraction and biosensoric detection will be developed, validated. All systems will be evaluated by end-users.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

UNIVERSITAT ROVIRA I VIRGILI
Address
C/ De L'escorxador S/n
43003 Tarragona
Spain

Participants (8)

ALIMENTOS BIOLOGICOS OLEANDER, S.A.
Spain
Address
Cl De La Font S/n
43391 Vinyols
AMYLUM EUROPE NV
Belgium
Address
Burchstraat 10
9300 Aalst
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Address
Universite Victor Segaien, 146 - Rue Leo Saignat
33076 Bordeaux
INSTITUTE OF MICROTECHNOLOGY MAINZ GMBH
Germany
Address
Carl-zeiss-strasse 18-20
55129 Mainz
KING'S COLLEGE LONDON
United Kingdom
Address
Strand
WC2R 2LS London
PLANT RESEARCH INTERNATIONAL B.V.
Netherlands
Address
Droevendaalsesteeg 1
Wageningen
TECHNOBIOCHIP S.C.A R.L.
Italy
Address
Via Della Marina 39
57030 Marciana
WAGENINGEN UNIVERSITY
Netherlands
Address
Costerweg 50
Wageningen