Quantification of coeliac disease toxic gluten in foodstuffs using a chip system with integrated extraction, fluidics and biosensoric detection step 2 of exploratory award exaw-1999-01542

Objective

The overall objective of the project is the development of a disposable microsystem with integrated optimal extraction and detection for the precise $ accurate quantitation of coeliac disease toxic gluten (CD-toxic gluten sequences of gluten to which coeliac disease sufferers show intorelance) in all types of foodstuffs. A standard universal protocol for extraction of gliadins and glutenins from all food states Enzyme linked assays and biosensors exploiting antibodies, antibody fragments and aptamers will be developed for the detection of CD-toxic gluten in raw, cooked, processed and unprocessed food. Finally, a disposable microsystem with integrated microstructured extraction and biosensoric detection will be developed, validated. All systems will be evaluated by end-users.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-1. - Key action Food, Nutrition and Health

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

UNIVERSITAT ROVIRA I VIRGILI

Address

C/ De L'escorxador S/n
43003 Tarragona
Spain

 

Participants (8)

ALIMENTOS BIOLOGICOS OLEANDER, S.A.

Spain

Address

Cl De La Font S/n
43391 Vinyols

 

AMYLUM EUROPE NV

Belgium

Address

Burchstraat 10
9300 Aalst

 

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

Address

Universite Victor Segaien, 146 - Rue Leo Saignat
33076 Bordeaux

 

INSTITUTE OF MICROTECHNOLOGY MAINZ GMBH

Germany

Address

Carl-zeiss-strasse 18-20
55129 Mainz

 

KING'S COLLEGE LONDON

United Kingdom

Address

Strand
WC2R 2LS London

 

PLANT RESEARCH INTERNATIONAL B.V.

Netherlands

Address

Droevendaalsesteeg 1
Wageningen

 

TECHNOBIOCHIP S.C.A R.L.

Italy

Address

Via Della Marina 39
57030 Marciana

 

WAGENINGEN UNIVERSITY

Netherlands

Address

Costerweg 50
Wageningen