Despite the impact that viruses have on aquatic organisms, relatively little is known about what farmers can do to prevent and treat viral diseases and how fish and invertebrates fight these infections. Thus, the project aims to characterise anti-viral innate immunity in fish, bivalves and crustaceans in order to provide new approach for the control of viral infections in aquaculture species. Some molecules and genes involved in anti-viral innate inhumanity will be defined and compared in different species. Selected anti-viral effectors will be monitored in vitro and in vivo assays potential anti-viral effects in different cellular and animal models. Furthermore, expression of selected molecules encoding genes will be analysed in healthy and virus-infected individuals. Candidate molecules and genes will be supplied for further exploitation in aquaculture and development of control tools against human and animal viral diseases.
Funding SchemeCSC - Cost-sharing contracts
DT4 8UB Weymouth
G11 5JR Glasgow