Objective
The consortium assembled here will contribute to the development of new anti-inflammatory drugs for clinical use in the European Union and beyond by identifying medicinal plant extracts with NF-kappa inhibitory activity and/or inhibitory effects on targets of the inflammatory cascade in peripheral and CNStissues. These targets will include, for example, IL-1beta, TNFalpha, PGE2, and IL-6. Subsequently the compounds mediating this inhibitory effect will be isolated and their structure elucidated. The consortium has the capacity to evaluate the extracts in a large set of targets related to the transcriptional activation of gene products of relevance for inflammatory, immunomodulatory and apoptotic activity. Select compounds will be further studied in in-vivo as well as in-Microsystems and we expect that this research will form the basis for preclinical and clinical development.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
WC1E7HU LONDON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.