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Content archived on 2024-06-17

Exploiting new solutes from hyperthermophiles for the preservation of biomaterials: cell factories for production of hypersolutes

Objective

Hyper solutes, compatible solutes from hyperthermophiles, are superior to their mesospheric counterparts in the preservation of the performance of a wide variety of biomaterials, ranging from proteins to whole cells, skin and artificial tissues. A major bottleneck for industrial applications of hyper solutes is the large-scale production at a competitive cost. The major goal of this project is the development of cell systems eternised for the production of mannosylglycerate; the most widely distributed hyper solute. Two strategies will be pursued:
i) engineering of expression and secretion systems in suitable hosts;
ii) optimisation of fermentation of natural producers. Trials will be conducted that will widen the range of application of mannosylglycerate. The involvement of industrial partners ensures that the results will reach end-users.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA
EU contribution
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Address
Avenida da Republica, Estacao Agronomica Nacional
OEIRAS
Portugal

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Total cost

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Participants (8)

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