Objetivo PM10 and PM2, 5 ambient particulate fractions collected in Amsterdam, Lodi, Oslo and Rome and the Dutch sea-side will be characterised by physical-chemical and immunological parameters. The samples will be screened for respiratory allergic and inflammatory potential and positive findings will undergo verification in vivo respiratory allergic and inflammatory models. Mechanisms underlying modulation of molecular and cellular functions of the immune system, of signalling pathways in rat and human epithelial lung cell cultures, and of in vivo respiratory immune responses will be clarified. Mechanistic information is important for extrapolating the results from the experimental models to the human situation. The outcome of these studies will be communicated to policymakers, the public and industry as basis for preventive action. Ámbito científico medical and health sciencesbasic medicineimmunologymedical and health sciencesclinical medicineallergology Programa(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Tema(s) 1.1.1.-4. - Key action Environment and Health Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador NORWEGIAN INSTITUTE OF PUBLIC HEALTH Aportación de la UE Sin datos Dirección 0403 OSLO Noruega Ver en el mapa Coste total Sin datos Participantes (3) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT Países Bajos Aportación de la UE Sin datos Dirección Antonie van Leeuwenhoeklaan 9 3720 BA BILTHOVEN Ver en el mapa Coste total Sin datos THE NOFER INSTITUTE OF OCCUPATIONAL MEDICINE Polonia Aportación de la UE Sin datos Dirección Teresy Street 8 90 950 LODZ Ver en el mapa Coste total Sin datos WORLD HEALTH ORGANIZATION Italia Aportación de la UE Sin datos Dirección via Francesco Crispi, 10 00187 ROMA Ver en el mapa Coste total Sin datos
