Cel PM10 and PM2, 5 ambient particulate fractions collected in Amsterdam, Lodi, Oslo and Rome and the Dutch sea-side will be characterised by physical-chemical and immunological parameters. The samples will be screened for respiratory allergic and inflammatory potential and positive findings will undergo verification in vivo respiratory allergic and inflammatory models. Mechanisms underlying modulation of molecular and cellular functions of the immune system, of signalling pathways in rat and human epithelial lung cell cultures, and of in vivo respiratory immune responses will be clarified. Mechanistic information is important for extrapolating the results from the experimental models to the human situation. The outcome of these studies will be communicated to policymakers, the public and industry as basis for preventive action. Dziedzina nauki medical and health sciencesbasic medicineimmunologymedical and health sciencesclinical medicineallergology Program(-y) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Temat(-y) 1.1.1.-4. - Key action Environment and Health Zaproszenie do składania wniosków Data not available System finansowania CSC - Cost-sharing contracts Koordynator NORWEGIAN INSTITUTE OF PUBLIC HEALTH Wkład UE Brak danych Adres 0403 OSLO Norwegia Zobacz na mapie Koszt całkowity Brak danych Uczestnicy (3) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT Niderlandy Wkład UE Brak danych Adres Antonie van Leeuwenhoeklaan 9 3720 BA BILTHOVEN Zobacz na mapie Koszt całkowity Brak danych THE NOFER INSTITUTE OF OCCUPATIONAL MEDICINE Polska Wkład UE Brak danych Adres Teresy Street 8 90 950 LODZ Zobacz na mapie Koszt całkowity Brak danych WORLD HEALTH ORGANIZATION Włochy Wkład UE Brak danych Adres via Francesco Crispi, 10 00187 ROMA Zobacz na mapie Koszt całkowity Brak danych