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Content archived on 2024-05-24

Mechanisms of ageing in extracellular matrices (AGEING ECM)

Objective

A major aspect of the ageing process in the human population is the loss of suppleness of extra cellular matrix tissues (such as skin, tendon, ligaments and blood vessels) and a consequential decline in the flexibility of joints, circulatory efficiency, skin integrity, etc., leads to impaired quality of life. The research proposed specifically aims to elucidate the cellular and molecular mechanisms of ECM tissue ageing. Three differing hypotheses ageing =
(a) impaired turnover,
(b) accumulated injury or
(c) impaired cell signalling are tested in distinct and interlaced work packages underpinned by a cross-prograrrnne use of expertise in cell and molecular biology, biophysics and structural biology. The project aims to formulate anti-ageing strategies based on the fundamental knowledge gained.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
EU contribution
No data
Address
INRA Theix
63122 ST GENES CHAMPANELLE
France

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (3)

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