Obiettivo Currently, clinical diagnosis and monitoring of bladder cancer (BC) relies on invasive, highly costly cystoscopy. Additionally, due to high recurrence rates BC treatment is associated with frequent follow-up of patients, making BC one of the most costly types of cancer in terms of management cost. Thus there is a clear clinical need for the development of new approaches for early detection of recurrence and progression.Our proposal is based on the identification of novel biomarkers (BM) for BC recurrence and progression in urine and powerful technological platforms as extensive foreground work of the involved partners in the framework of FP7 EU projects DECanBio and GENINCA. The objective of TransBioBC is to translate this foreground work in the field of BC and to specifically employ the involved technologies (CE-MS and micro-ELISA), represented by the participating SMEs, for the development of non-invasive urine tests for routine monitoring of BC recurrence and progression. Our project uniquely integrates leading BC clinical experts with experts on proteome analysis and high throughput immunoassay development in an implementation-oriented workflow. Strict monitoring of assay analytical performance, and properly collected and well characterized clinical samples from existing sufficiently powered BC cohorts are combined with in-depth knowledge of regulatory requirements, analysis approaches to define added value and well designed business plans including multi-stakeholder dissemination and exploitation plans.Collectively, TransBioBC will provide strong evidence for utility of the new BM directly in BC clinical management and as a secondary aim for usage in clinical trials and drug development. Campo scientifico medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomicsmedical and health sciencesclinical medicineoncologybladder cancerengineering and technologymedical engineeringmedical laboratory technologylaboratory samples analysis Programma(i) FP7-HEALTH - Specific Programme "Cooperation": Health Argomento(i) HEALTH.2013.0-1 - Boosting the translation of health research projects' results into innovative applications for health Invito a presentare proposte FP7-HEALTH-2013-INNOVATION-2 Vedi altri progetti per questo bando Meccanismo di finanziamento CP-FP - Small or medium-scale focused research project Coordinatore IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON Contributo UE € 760 964,80 Indirizzo SORANOU EFESIOU 4 115 27 Athina Grecia Mostra sulla mappa Regione Αττική Aττική Κεντρικός Τομέας Αθηνών Tipo di attività Research Organisations Contatto amministrativo Dimitris Raptis (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (3) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto MOSAIQUES DIAGNOSTICS GMBH Germania Contributo UE € 1 119 089,00 Indirizzo ROTENBURGER STRASSE 20 30659 Hannover Mostra sulla mappa Regione Niedersachsen Hannover Region Hannover Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Harald Mischak (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato DIAGNOSWISS SA Svizzera Contributo UE € 831 344,00 Indirizzo ZI LES ILETTES SECTEUR 4 1870 MONTHEY Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Frédéric Reymond (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato FUNDACION SECTOR PUBLICO ESTATAL CENTRO NACIONAL INVESTIGACIONES ONCOLOGICAS CARLOS III Spagna Contributo UE € 548 960,80 Indirizzo C MELCHOR FERNANDEZ ALMAGRO 3 28029 Madrid Mostra sulla mappa Regione Comunidad de Madrid Comunidad de Madrid Madrid Tipo di attività Research Organisations Contatto amministrativo Lilit Manukyan (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
