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Infrastructure for NMR, EM and X-rays for translational research

Objective

Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials.
iNEXT (infrastructure for NMR, EM and X-rays for Translational research) will provide high-end structural biology instrumentation and expertise, facilitating expert and non-expert European users to translate their fundamental research into biomedical and biotechnological applications.
iNEXT brings together leading European structural biology facilities under one interdisciplinary organizational umbrella and includes synchrotron sites for X-rays, NMR centers with ultra-high field instruments, and, for the first time, advanced electron microscopy and light imaging facilities. Together with key partners in biological and biomedical institutions, partners focusing on training and dissemination activities, and ESFRI projects (Instruct, Euro-BioImaging, EU-OPENSCREEN and future neutron-provider ESS), iNEXT forms an inclusive European network of world class.
iNEXT joint research projects (fragment screening for drug development, membrane protein structure, and multimodal cellular imaging) and networking, training and transnational access activities will be important for SMEs, established industries and academics alike. In particular, iNEXT will provide novel access modes to attract new and non-expert users, which are often hindered from engaging in structural biology projects through lack of instrumentation and expertise: a Structural Audit procedure, whereby a sample is assessed for its suitability for structural studies; Enhanced Project Support, allowing users to get expert help in an iNEXT facility; and High-End Data Collection, enabling experienced users to take full benefit of the iNEXT state-of-the-art equipment.

Field of science

  • /engineering and technology/industrial biotechnology/biomaterials
  • /natural sciences/biological sciences/molecular biology/structural biology
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes
  • /medical and health sciences/basic medicine/pharmacology and pharmacy/pharmaceutical drug/vaccines

Call for proposal

H2020-INFRAIA-2014-2015
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSITEIT UTRECHT
Address
Heidelberglaan 8
3584 CS Utrecht
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 999 724

Participants (24)

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 2 395 127
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
DIAMOND LIGHT SOURCE LIMITED
United Kingdom
EU contribution
€ 1 155 074,25
Address
Diamond House Harwell Science & Innovation Campus Chilton
0X11 0DE Didcot
Activity type
Other
CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE
Italy
EU contribution
€ 740 695,50
Address
Piazza San Marco 4
50121 Firenze
Activity type
Higher or Secondary Education Establishments
JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN
Germany
EU contribution
€ 684 776,50
Address
Theodor W Adorno Platz 1
60323 Frankfurt Am Main
Activity type
Higher or Secondary Education Establishments
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Netherlands
EU contribution
€ 683 500
Address
Plesmanlaan 121
1066 CX Amsterdam
Activity type
Research Organisations
Masarykova univerzita
Czechia
EU contribution
€ 470 672
Address
Zerotinovo Namesti 9
60177 Brno Stred
Activity type
Higher or Secondary Education Establishments
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 428 600
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
FORSCHUNGSVERBUND BERLIN EV
Germany
EU contribution
€ 438 609
Address
Rudower Chaussee 17
12489 Berlin
Activity type
Research Organisations
SYNCHROTRON SOLEIL SOCIETE CIVILE
France
EU contribution
€ 385 925
Address
L Orme Des Merisiers
91190 Saint Aubin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LUNDS UNIVERSITET
Sweden
EU contribution
€ 312 925,50
Address
Paradisgatan 5C
22100 Lund
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT LEIDEN
Netherlands
EU contribution
€ 272 968
Address
Rapenburg 70
2311 EZ Leiden
Activity type
Higher or Secondary Education Establishments
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
EU contribution
€ 223 562,50
Address
Albinusdreef 2
2333 ZA Leiden
Activity type
Higher or Secondary Education Establishments
EUROPEAN SYNCHROTRON RADIATION FACILITY
France
EU contribution
€ 203 250
Address
71 Avenue Des Martyrs
38000 Grenoble
Activity type
Research Organisations
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 179 625
Address
Rue Michel Ange 3
75794 Paris
Activity type
Research Organisations
INSTRUCT ACADEMIC SERVICES LIMITED
United Kingdom
EU contribution
€ 128 500
Address
University Of Oxford Offices Wellington Square
OX1 2JD Oxford
Activity type
Other
AARHUS UNIVERSITET
Denmark
EU contribution
€ 92 750
Address
Nordre Ringgade 1
8000 Aarhus C
Activity type
Higher or Secondary Education Establishments
EUROPEAN SPALLATION SOURCE ERIC
Sweden
EU contribution
€ 47 000
Address
Odarslovsvagen 113
224 84 Lund
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
EUROPEAN SPALLATION SOURCE ESS AB

Participation ended

Sweden
EU contribution
€ 0
Address
Box 176
22100 Lund
Activity type
Research Organisations
EOTVOS LORAND TUDOMANYEGYETEM
Hungary
EU contribution
€ 31 250
Address
Egyetem Ter 1-3
1053 Budapest
Activity type
Higher or Secondary Education Establishments
INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA

Participation ended

Portugal
EU contribution
€ 0
Address
Avenida Da Republica, Estacao Agronomica Nacional
2784-505 Oeiras
Activity type
Higher or Secondary Education Establishments
UNIVERSIDADE NOVA DE LISBOA
Portugal
EU contribution
€ 31 250
Address
Campus De Campolide
1099 085 Lisboa
Activity type
Higher or Secondary Education Establishments
OULUN YLIOPISTO
Finland
EU contribution
€ 31 250
Address
Pentti Kaiteran Katu 1
90014 Oulu
Activity type
Higher or Secondary Education Establishments
PANEPISTIMIO PATRON
Greece
EU contribution
€ 31 250
Address
University Campus Rio Patras
265 04 Rio Patras
Activity type
Higher or Secondary Education Establishments
WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 31 250
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments