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Infrastructure for NMR, EM and X-rays for translational research

Infrastructure for NMR, EM and X-rays for translational research

Objective

Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials.
iNEXT (infrastructure for NMR, EM and X-rays for Translational research) will provide high-end structural biology instrumentation and expertise, facilitating expert and non-expert European users to translate their fundamental research into biomedical and biotechnological applications.
iNEXT brings together leading European structural biology facilities under one interdisciplinary organizational umbrella and includes synchrotron sites for X-rays, NMR centers with ultra-high field instruments, and, for the first time, advanced electron microscopy and light imaging facilities. Together with key partners in biological and biomedical institutions, partners focusing on training and dissemination activities, and ESFRI projects (Instruct, Euro-BioImaging, EU-OPENSCREEN and future neutron-provider ESS), iNEXT forms an inclusive European network of world class.
iNEXT joint research projects (fragment screening for drug development, membrane protein structure, and multimodal cellular imaging) and networking, training and transnational access activities will be important for SMEs, established industries and academics alike. In particular, iNEXT will provide novel access modes to attract new and non-expert users, which are often hindered from engaging in structural biology projects through lack of instrumentation and expertise: a Structural Audit procedure, whereby a sample is assessed for its suitability for structural studies; Enhanced Project Support, allowing users to get expert help in an iNEXT facility; and High-End Data Collection, enabling experienced users to take full benefit of the iNEXT state-of-the-art equipment.

Coordinator

UNIVERSITEIT UTRECHT

Address

Heidelberglaan 8
3584 Cs Utrecht

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 999 724

Participants (24)

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EUROPEAN MOLECULAR BIOLOGY LABORATORY

Germany

EU Contribution

€ 2 395 127

DIAMOND LIGHT SOURCE LIMITED

United Kingdom

EU Contribution

€ 1 155 074,25

CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE

Italy

EU Contribution

€ 740 695,50

JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN

Germany

EU Contribution

€ 684 776,50

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS

Netherlands

EU Contribution

€ 683 500

Masarykova univerzita

Czechia

EU Contribution

€ 470 672

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Spain

EU Contribution

€ 428 600

FORSCHUNGSVERBUND BERLIN EV

Germany

EU Contribution

€ 438 609

SYNCHROTRON SOLEIL SOCIETE CIVILE

France

EU Contribution

€ 385 925

LUNDS UNIVERSITET

Sweden

EU Contribution

€ 312 925,50

UNIVERSITEIT LEIDEN

Netherlands

EU Contribution

€ 272 968

ACADEMISCH ZIEKENHUIS LEIDEN

Netherlands

EU Contribution

€ 223 562,50

EUROPEAN SYNCHROTRON RADIATION FACILITY

France

EU Contribution

€ 203 250

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

France

EU Contribution

€ 179 625

INSTRUCT ACADEMIC SERVICES LIMITED

United Kingdom

EU Contribution

€ 128 500

AARHUS UNIVERSITET

Denmark

EU Contribution

€ 92 750

EUROPEAN SPALLATION SOURCE ERIC

Sweden

EU Contribution

€ 47 000

EUROPEAN SPALLATION SOURCE ESS AB

Sweden

EOTVOS LORAND TUDOMANYEGYETEM

Hungary

EU Contribution

€ 31 250

INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA

Portugal

UNIVERSIDADE NOVA DE LISBOA

Portugal

EU Contribution

€ 31 250

OULUN YLIOPISTO

Finland

EU Contribution

€ 31 250

PANEPISTIMIO PATRON

Greece

EU Contribution

€ 31 250

WEIZMANN INSTITUTE OF SCIENCE

Israel

EU Contribution

€ 31 250

Project information

Grant agreement ID: 653706

Status

Ongoing project

  • Start date

    1 September 2015

  • End date

    31 August 2019

Funded under:

H2020-EU.1.4.1.2.

  • Overall budget:

    € 9 999 534,25

  • EU contribution

    € 9 999 534,25

Coordinated by:

UNIVERSITEIT UTRECHT

Netherlands