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Infrastructure for NMR, EM and X-rays for translational research

Objectif

Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials.
iNEXT (infrastructure for NMR, EM and X-rays for Translational research) will provide high-end structural biology instrumentation and expertise, facilitating expert and non-expert European users to translate their fundamental research into biomedical and biotechnological applications.
iNEXT brings together leading European structural biology facilities under one interdisciplinary organizational umbrella and includes synchrotron sites for X-rays, NMR centers with ultra-high field instruments, and, for the first time, advanced electron microscopy and light imaging facilities. Together with key partners in biological and biomedical institutions, partners focusing on training and dissemination activities, and ESFRI projects (Instruct, Euro-BioImaging, EU-OPENSCREEN and future neutron-provider ESS), iNEXT forms an inclusive European network of world class.
iNEXT joint research projects (fragment screening for drug development, membrane protein structure, and multimodal cellular imaging) and networking, training and transnational access activities will be important for SMEs, established industries and academics alike. In particular, iNEXT will provide novel access modes to attract new and non-expert users, which are often hindered from engaging in structural biology projects through lack of instrumentation and expertise: a Structural Audit procedure, whereby a sample is assessed for its suitability for structural studies; Enhanced Project Support, allowing users to get expert help in an iNEXT facility; and High-End Data Collection, enabling experienced users to take full benefit of the iNEXT state-of-the-art equipment.

Appel à propositions

H2020-INFRAIA-2014-2015
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Coordinateur

UNIVERSITEIT UTRECHT
Adresse
Heidelberglaan 8
3584 CS Utrecht
Pays-Bas
Type d’activité
Higher or Secondary Education Establishments
Contribution de l’UE
€ 999 724

Participants (22)

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Allemagne
Contribution de l’UE
€ 2 395 127
Adresse
Meyerhofstrasse 1
69117 Heidelberg
Type d’activité
Research Organisations
DIAMOND LIGHT SOURCE LIMITED
United Kingdom
Contribution de l’UE
€ 1 155 074,25
Adresse
Diamond House Harwell Science & Innovation Campus Chilton
0X11 0DE Didcot
Type d’activité
Other
CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE
Italie
Contribution de l’UE
€ 740 695,50
Adresse
Piazza San Marco 4
50121 Firenze
Type d’activité
Higher or Secondary Education Establishments
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Allemagne
Contribution de l’UE
€ 684 776,50
Adresse
Theodor W Adorno Platz 1
60323 Frankfurt Am Main
Type d’activité
Higher or Secondary Education Establishments
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Pays-Bas
Contribution de l’UE
€ 683 500
Adresse
Plesmanlaan 121
1066 CX Amsterdam
Type d’activité
Research Organisations
Masarykova univerzita
Tchéquie
Contribution de l’UE
€ 470 672
Adresse
Zerotinovo Namesti 9
601 77 Brno
Type d’activité
Higher or Secondary Education Establishments
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Espagne
Contribution de l’UE
€ 428 600
Adresse
Calle Serrano 117
28006 Madrid
Type d’activité
Research Organisations
FORSCHUNGSVERBUND BERLIN EV
Allemagne
Contribution de l’UE
€ 438 609
Adresse
Rudower Chaussee 17
12489 Berlin
Type d’activité
Research Organisations
Société Civile Synchrotron SOLEIL
France
Contribution de l’UE
€ 385 925
Adresse
L'orme Des Merisiers
91192 Gif Sur Yvette
Type d’activité
Research Organisations
LUNDS UNIVERSITET
Suède
Contribution de l’UE
€ 312 925,50
Adresse
Paradisgatan 5C
22100 Lund
Type d’activité
Higher or Secondary Education Establishments
UNIVERSITEIT LEIDEN
Pays-Bas
Contribution de l’UE
€ 272 968
Adresse
Rapenburg 70
2311 EZ Leiden
Type d’activité
Higher or Secondary Education Establishments
ACADEMISCH ZIEKENHUIS LEIDEN
Pays-Bas
Contribution de l’UE
€ 223 562,50
Adresse
Albinusdreef 2
2333 ZA Leiden
Type d’activité
Higher or Secondary Education Establishments
EUROPEAN SYNCHROTRON RADIATION FACILITY
France
Contribution de l’UE
€ 203 250
Adresse
71 Avenue Des Martyrs
38000 Grenoble
Type d’activité
Research Organisations
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
Contribution de l’UE
€ 179 625
Adresse
Rue Michel Ange 3
75794 Paris
Type d’activité
Research Organisations
INSTRUCT ACADEMIC SERVICES LIMITED
United Kingdom
Contribution de l’UE
€ 128 500
Adresse
University Of Oxford Offices Wellington Square
OX1 2JD Oxford
Type d’activité
Other
AARHUS UNIVERSITET
Danemark
Contribution de l’UE
€ 92 750
Adresse
Nordre Ringgade 1
8000 Aarhus C
Type d’activité
Higher or Secondary Education Establishments
EUROPEAN SPALLATION SOURCE ERIC
Suède
Contribution de l’UE
€ 47 000
Adresse
Odarslovsvagen 113
224 84 Lund
Type d’activité
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
EOTVOS LORAND TUDOMANYEGYETEM
Hongrie
Contribution de l’UE
€ 31 250
Adresse
Egyetem Ter 1-3
1053 Budapest
Type d’activité
Higher or Secondary Education Establishments
UNIVERSIDADE NOVA DE LISBOA
Portugal
Contribution de l’UE
€ 31 250
Adresse
Campus De Campolide
1099 085 Lisboa
Type d’activité
Higher or Secondary Education Establishments
OULUN YLIOPISTO
Finlande
Contribution de l’UE
€ 31 250
Adresse
Pentti Kaiteran Katu 1
90014 Oulu
Type d’activité
Higher or Secondary Education Establishments
PANEPISTIMIO PATRON
Greece
Contribution de l’UE
€ 31 250
Adresse
University Campus Rio Patras
265 04 Rio Patras
Type d’activité
Higher or Secondary Education Establishments
WEIZMANN INSTITUTE OF SCIENCE
Israël
Contribution de l’UE
€ 31 250
Adresse
Herzl Street 234
7610001 Rehovot
Type d’activité
Higher or Secondary Education Establishments