Obiettivo Functional magnetic resonance imaging (fMRI) has become an indispensable tool in neuroscience to study human brain function non-invasively. However, translation of fMRI to investigate function of the second major component of the central nervous system, the spinal cord, has been severely hampered by technical difficulties. Two major challenges for spinal fMRI relate to the anatomy: (i) severe static image distortion caused by vertebrae and the lungs and (ii) dynamic signal instability introduced by breathing. I propose to address these problems by leveraging my expertise with cutting-edge technology for magnetic field compensation, available only to a few sites world-wide including my host institute in Oxford. These advances will enable me to take advantage of the signal-to-noise ratio improvement of ultra-high field (7 Tesla) MRI scanners, which has been clearly demonstrated in the brain but has remained elusive for the spine. The final stage of this project will deploy these methods on a collaborative project investigating the neurobiological mechanisms of pain in the spine. This project will enable me to build strategically on my dual training in engineering and medicine to develop an inter-disciplinary research profile at the interface of neuroscience and methodology. Campo scientifico natural sciencesbiological sciencesneurobiologymedical and health sciencesbasic medicineanatomy and morphologyengineering and technologymedical engineeringdiagnostic imagingmagnetic resonance imaging Programma(i) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Argomento(i) MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) Invito a presentare proposte H2020-MSCA-IF-2014 Vedi altri progetti per questo bando Meccanismo di finanziamento MSCA-IF-EF-ST - Standard EF Coordinatore THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Contribution nette de l'UE € 183 454,80 Indirizzo WELLINGTON SQUARE UNIVERSITY OFFICES OX1 2JD Oxford Regno Unito Mostra sulla mappa Regione South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Tipo di attività Higher or Secondary Education Establishments Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 183 454,80
