Objective
Probiotics are defined as live microorganisms with a long history of safe use and a robust evidence for providing beneficial effects to the consumer. The majority of probiotic bacteria belong to Lactobacillus genus, which includes a large number of GRAS species, essential in fermented food production and for use as food preservatives. Lactobacilli have also a range of non-food applications, such as industrial production of lactate for the textile industry in environmentally friendlier ways than chemical synthesis.
Despite their broad use, health claims approval by EFSA for probiotics is challenging due to scientific difficulties in validating probiotic mechanisms and a lack of proper strain characterization. Although there has been a surge in research into probiotics, the conversion into actual claims and compliance with the regulatory requirements has proved difficult.
The aim of the project is to perform forensically detailed comparative genomic analysis of Lactobacillus species to i) unravel the genetic backbone that has been moulded by genome decay and gene acquisition ii) delineate the genetic features and molecular mechanisms that underpin their health-promoting effects and suitability for use, and iii) identify genes associated with the phenotypes for new food applications.
A deeper insight into the safety-related issues for food strains will provide a comprehensive assessment on risk factors to be transferred to companies as supplementary safety guidelines for successful health claim proposals. Data obtained will be used to develop new dietary solutions and safe non-food applications, thus increasing manufacturers’ interest in placing beneficial products on the market and meeting the consumer’s ambitions to live healthier.
Within the project, the applicant will have the chance to perform high-level research with leading scientists and create a link between academic institutions and companies for efficient technology transfer and novel industrial solutions.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- engineering and technology materials engineering textiles
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
- natural sciences biological sciences genetics genomes
- medical and health sciences basic medicine pharmacology and pharmacy drug resistance antibiotic resistance
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2014
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
T12 YN60 Cork
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.