Objective
Concept: NanoFASE will deliver an integrated Exposure Assessment Framework, including methods, parameter values, model and guidance that will allow Industry to assess the full diversity of industrial nano-enabled products to a standard acceptable in regulatory registrations. Methods to assess how use phases, waste streams and environmental compartments (air, soil, water biota) act as “reactors” in modifying and transporting ENMs will be developed and used to derive parameter values. Our nanospecific models will be integrated with the existing multi-media fate model SimpleBox4Nano for use in EUSES and also develop into a flexible multi-media model for risk assessment at different scales and complexities. Information on release form, transformation and transport processes for product relevant ENMs will allow grouping into Functional Fate Groups according to their “most probable” fate pathways as a contribution to safe-by-design based on fate.
Methodology: Inventories of material release forms along the product value chain are established. We then study how released ENMs transform from initial reactive states to modified forms with lower energy states in which nanospecific properties may be lost. Transport studies assess material fluxes within/between compartments. The experimental work underpins models describing ENM transformation and transport. Open access is provided to the models suitable for incorporation into existing exposure assessment tools (e.g. SimpleBox4Nano) and for more detailed assessment. Framework completeness is validated by case studies.
Impact: Identified links between ENM material properties and fate outcome (e.g. safe-by-design). Improved representation of nanospecific processes in existing key fate and exposure assessment tools (e.g. SimpleBox4Nano in EUSES). Contribution to standardization. GIS framework to support predictive assessment, catchment and point source management of ENM releases.
Fields of science
Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
SN2 1FL Swindon
United Kingdom
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Participants (35)
B15 2TT Birmingham
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08225 Terrassa
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8600 Dubendorf
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47229 Duisburg
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405 30 Goeteborg
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1010 Wien
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6708 PB Wageningen
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OX1 2JD Oxford
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70599 Stuttgart
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
08213 Polinya Barcelona
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NG7 3EF Nottingham
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
46117 Liberec
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08007 Barcelona
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90-268 Lodz
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
544 01 Dvur Kralove Nad Labem
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
08018 Barcelona
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
8600 Dubendorf
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60550 Verneuil En Halatte
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7558 Strada Tschlin
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
2595 DA Den Haag
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3721 MA Bilthoven
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1211 Geneve
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WR14 1XZ Malvern
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PL4 8AA Plymouth
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1000 Ljubljana
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1081 HV Amsterdam
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3810-193 Aveiro
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6708 PB Wageningen
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30123 Venezia
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1111 Sofia
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
75005 Paris
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
SN5 4EJ Swindon
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
194 81 Upplands Vasby
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750 07 Uppsala
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82152 Planegg
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.