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Effects of maternal gestational adiposity on fetal development and perinatal, postnatal and next generation health.

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Publications

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Author(s): Robin N Beaumont, Nicole M Warrington, Alana Cavadino, Jessica Tyrrell, Michael Nodzenski, Momoko Horikoshi, Frank Geller, Ronny Myhre, Rebecca C Richmond, Lavinia Paternoster, Jonathan P Bradfield, Eskil Kreiner-Møller, Ville Huikari, Sarah Metrustry, Kathryn L Lunetta, Jodie N Painter, Jouke-Jan Hottenga, Catherine Allard, Sheila J Barton, Ana Espinosa, Julie A Marsh, Catherine Potter, Ge Zhang
Published in: Human Molecular Genetics, Issue 27/4, 2018, Page(s) 742-756, ISSN 0964-6906
DOI: 10.1093/hmg/ddx429

Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence

Author(s): Qin Wang, Peter Würtz, Kirsi Auro, Laure Morin-Papunen, Antti J Kangas, Pasi Soininen, Mika Tiainen, Tuulia Tynkkynen, Anni Joensuu, Aki S Havulinna, Kristiina Aalto, Marko Salmi, Stefan Blankenberg, Tanja Zeller, Jorma Viikari, Mika Kähönen, Terho Lehtimäki, Veikko Salomaa, Sirpa Jalkanen, Marjo-Riitta Järvelin, Markus Perola, Olli T Raitakari, Debbie A Lawlor, Johannes Kettunen, Mika Ala-Ko
Published in: International Journal of Epidemiology, Issue 45/5, 2016, Page(s) 1445-1457, ISSN 0300-5771
DOI: 10.1093/ije/dyw147

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

Author(s): Jessica Tyrrell, Rebecca C. Richmond, Tom M. Palmer, Bjarke Feenstra, Janani Rangarajan, Sarah Metrustry, Alana Cavadino, Lavinia Paternoster, Loren L. Armstrong, N. Maneka G. De Silva, Andrew R. Wood, Momoko Horikoshi, Frank Geller, Ronny Myhre, Jonathan P. Bradfield, Eskil Kreiner-Møller, Ville Huikari, Jodie N. Painter, Jouke-Jan Hottenga, Catherine Allard, Diane J. Berry, Luigi Bouchard, Shik
Published in: JAMA, Issue 315/11, 2016, Page(s) 1129, ISSN 0098-7484
DOI: 10.1001/jama.2016.1975

Using genetic variation to explore the causal effect of maternal pregnancy adiposity on future offspring adiposity

Author(s): Richmond RC, Timpson NJ, Felix JF, Palmer T, Gaillard R, McMahon G, Davey Smith G, Jaddoe VW, Lawlor DA
Published in: PloS Medicine, Issue 2017, 2017, Page(s) e1002221, ISSN 1549-1277
DOI: 10.1371/journal.pmed.1002221

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

Author(s): Ralph McGinnis, Valgerdur Steinthorsdottir, Nicholas O Williams, Gudmar Thorleifsson, Scott Shooter, Sigrun Hjartardottir, Suzannah Bumpstead, Lilja Stefansdottir, Lucy Hildyard, Jon K Sigurdsson, John P Kemp, Gabriela B Silva, Liv Cecilie V Thomsen, Tiina Jääskeläinen, Eero Kajantie, Sally Chappell, Noor Kalsheker, Ashley Moffett, Susan Hiby, Wai Kwong Lee, Sandosh Padmanabhan, Nigel A B Simps
Published in: Nature Genetics, Issue 49/8, 2017, Page(s) 1255-1260, ISSN 1061-4036
DOI: 10.1038/ng.3895

Maternal and fetal genetic contribution to gestational weight gain

Author(s): N M Warrington, R Richmond, B Fenstra, R Myhre, R Gaillard, L Paternoster, C A Wang, R N Beaumont, S Das, M Murcia, S J Barton, A Espinosa, E Thiering, M Atalay, N Pitkänen, I Ntalla, A E Jonsson, R Freathy, V Karhunen, C M T Tiesler, C Allard, A Crawford, S M Ring, M Melbye, P Magnus, F Rivadeneira, L Skotte, T Hansen, J Marsh, M Guxens, J W Holloway, H Grallert, V W V Jaddoe, W L Lowe Jr, T Rou
Published in: International Journal of Obesity, Issue 42/4, 2017, Page(s) 775-784, ISSN 0307-0565
DOI: 10.1038/ijo.2017.248

Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing them

Author(s): Deborah Lawlor, Rebecca Richmond, Nicole Warrington, George McMahon, George Davey Smith, Jack Bowden, David M Evans
Published in: Wellcome Open Research, Issue 2, 2013, Page(s) 11, ISSN 2398-502X
DOI: 10.12688/wellcomeopenres.10567.1

Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy

Author(s): N Patel, K M Godfrey, D Pasupathy, J Levin, A C Flynn, L Hayes, A L Briley, R Bell, D A Lawlor, E Oteng-Ntim, S M Nelson, S C Robson, N Sattar, C Singh, J Wardle, S L White, P T Seed, L Poston
Published in: International Journal of Obesity, 2017, ISSN 0307-0565
DOI: 10.1038/ijo.2017.44

Metabolic signatures of birthweight in 18 288 adolescents and adults

Author(s): Peter Würtz, Qin Wang, Marjo Niironen, Tuulia Tynkkynen, Mika Tiainen, Fotios Drenos, Antti J Kangas, Pasi Soininen, Michael R Skilton, Kauko Heikkilä, Anneli Pouta, Mika Kähönen, Terho Lehtimäki, Richard J Rose, Eero Kajantie, Markus Perola, Jaakko Kaprio, Johan G Eriksson, Olli T Raitakari, Debbie A Lawlor, George Davey Smith, Marjo-Riitta Järvelin, Mika Ala-Korpela, Kirsi Auro
Published in: International Journal of Epidemiology, Issue 45/5, 2016, Page(s) 1539-1550, ISSN 0300-5771
DOI: 10.1093/ije/dyw255

Causal inference—so much more than statistics

Author(s): Neil Pearce, Debbie A Lawlor
Published in: International Journal of Epidemiology, Issue 45/6, 2016, Page(s) 1895-1903, ISSN 0300-5771
DOI: 10.1093/ije/dyw328

Association of pre-pregnancy body mass index with offspring metabolic profile: Analyses of 3 European prospective birth cohorts

Author(s): Diana L. Santos Ferreira, Dylan M. Williams, Antti J. Kangas, Pasi Soininen, Mika Ala-Korpela, George Davey Smith, Marjo-Riitta Jarvelin, Debbie A. Lawlor
Published in: PLOS Medicine, Issue 14/8, 2017, Page(s) e1002376, ISSN 1549-1676
DOI: 10.1371/journal.pmed.1002376

Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort

Author(s): Judith S. Brand, Jane West, Derek Tuffnell, Philippa K. Bird, John Wright, Kate Tilling, Debbie A. Lawlor
Published in: BMC Medicine, Issue 16/1, 2018, ISSN 1741-7015
DOI: 10.1186/s12916-018-1191-7

Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence

Author(s): Wang Q, Würtz P, Auro K, Kangas AJ, Soininen P, Tiainen M, Tynkkynen T, Jokelainen J, Santalahti K, Salmi M, Blankenberg S, Zeller T, Viikari J, Kähönen M, Lehtimäki T, Salomaa V, Perola M, Jalkanen S, Järvelin M-R, Raitakari OT, Kettunen J, Lawlor DA*, Ala-Korpela M* (*equal senior authors)
Published in: BMC Medicine, Issue 2016, 2016, Page(s) 205, ISSN 1741-7015
DOI: 10.1186/s12916-016-0733-0

Growing up in Bradford: protocol for the age 7–11 follow up of the Born in Bradford birth cohort

Author(s): Philippa K Bird, Rosemary R. C. McEachan, Mark Mon-Williams, Neil Small, Jane West, Peter Whincup, John Wright, Elizabeth Andrews, Sally E Barber, Liam J B Hill, Laura Lennon, Dan Mason, Katy A Shire, Dagmar Waiblinger, Amanda H. Waterman, Deborah A. Lawlor, Kate E. Pickett
Published in: BMC Public Health, Issue 19/1, 2019, ISSN 1471-2458
DOI: 10.1186/s12889-019-7222-2

Association of maternal exposures with adiposity at age 4/5 years in white British and Pakistani children: findings from the Born in Bradford study

Author(s): Jane West, Gillian Santorelli, Peter H. Whincup, Lesley Smith, Naveed A. Sattar, Noel Cameron, Diane Farrar, Paul Collings, John Wright, Debbie A. Lawlor
Published in: Diabetologia, Issue 61/1, 2018, Page(s) 242-252, ISSN 0012-186X
DOI: 10.1007/s00125-017-4457-2

Triangulation in aetiological epidemiology

Author(s): Debbie A. Lawlor, Kate Tilling, George Davey Smith
Published in: International Journal of Epidemiology, 2017, Page(s) dyw314, ISSN 0300-5771
DOI: 10.1093/ije/dyw314

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

Author(s): Christel M. Middeldorp, Janine F. Felix, Anubha Mahajan, Mark I. McCarthy
Published in: European Journal of Epidemiology, Issue 34/3, 2019, Page(s) 279-300, ISSN 0393-2990
DOI: 10.1007/s10654-019-00502-9

Hyperglycaemia and risk of adverse perinatal outcomes: systematic review and meta-analysis

Author(s): Diane Farrar, Mark Simmonds, Maria Bryant, Trevor A Sheldon, Derek Tuffnell, Su Golder, Fidelma Dunne, Debbie A Lawlor
Published in: BMJ, 2016, Page(s) i4694, ISSN 1756-1833
DOI: 10.1136/bmj.i4694

Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

Author(s): Matias C. Vieira, Sara L. White, Nashita Patel, Paul T. Seed, Annette L. Briley, Jane Sandall, Paul Welsh, Naveed Sattar, Scott M. Nelson, Debbie A. Lawlor, Lucilla Poston, Dharmintra Pasupathy
Published in: BMC Medicine, Issue 15/1, 2017, ISSN 1741-7015
DOI: 10.1186/s12916-017-0956-8