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Effects of maternal gestational adiposity on fetal development and perinatal, postnatal and next generation health.

Pubblicazioni

Evidence of detrimental effects of prenatal alcohol exposure on offspring birthweight and neurodevelopment from a systematic review of quasi-experimental studies

Autori: Loubaba Mamluk, Timothy Jones, Sharea Ijaz, Hannah B Edwards, Jelena Savović, Verity Leach, Theresa H M Moore, Stephanie von Hinke, Sarah J Lewis, Jenny L Donovan, Deborah A Lawlor, George Davey Smith, Abigail Fraser, Luisa Zuccolo
Pubblicato in: International Journal of Epidemiology, Issue 49/6, 2020, Page(s) 1972-1995, ISSN 0300-5771
DOI: 10.1093/ije/dyz272

Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort

Autori: Gunn-Helen Moen, Ben Brumpton, Cristen Willer, Bjørn Olav Åsvold, Kåre I. Birkeland, Geng Wang, Michael C. Neale, Rachel M. Freathy, George Davey Smith, Deborah A. Lawlor, Robert M. Kirkpatrick, Nicole M. Warrington, David M. Evans
Pubblicato in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-19257-z

Metabolomics datasets in the Born in Bradford cohort

Autori: Kurt Taylor, Nancy McBride, Neil J Goulding, Kimberley Burrows, Dan Mason, Lucy Pembrey, Tiffany Yang, Rafaq Azad, John Wright, Deborah A Lawlor
Pubblicato in: Wellcome Open Research, Issue 5, 2020, Page(s) 264, ISSN 2398-502X
DOI: 10.12688/wellcomeopenres.16341.1

Bias in two-sample Mendelian randomization when using heritable covariable-adjusted summary associations

Autori: Fernando Pires Hartwig, Kate Tilling, George Davey Smith, Deborah A Lawlor, Maria Carolina Borges
Pubblicato in: International Journal of Epidemiology, 2021, ISSN 0300-5771
DOI: 10.1093/ije/dyaa266

Cardiometabolic health during early adulthood and risk of miscarriage: a prospective study

Autori: Maria C. Magnus, Diana D. S. Ferreira, Maria Carolina Borges, Kate Tilling, Deborah A. Lawlor, Abigail Fraser
Pubblicato in: Wellcome Open Research, Issue 5, 2020, Page(s) 205, ISSN 2398-502X
DOI: 10.12688/wellcomeopenres.16245.1

Associations of cord leptin and cord insulin with adiposity and blood pressure in White British and Pakistani children aged 4/5 years

Autori: Jane West, Gillian Santorelli, Paul Collings, Daniel Bingham, Peter Whincup, Naveed Sattar, Tom Norris, John Wright, Debbie A. Lawlor
Pubblicato in: Wellcome Open Research, Issue 4, 2019, Page(s) 157, ISSN 2398-502X
DOI: 10.12688/wellcomeopenres.15433.1

Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria

Autori: Tracy L McGregor, Karen A Hunt, Elaine Yee, Dan Mason, Paul Nioi, Simina Ticau, Marissa Pelosi, Perry R Loken, Sarah Finer, Deborah A Lawlor, Eric B Fauman, Qin Qin Huang, Christopher J Griffiths, Daniel G MacArthur, Richard C Trembath, Devin Oglesbee, John C Lieske, David V Erbe, John Wright, David A van Heel
Pubblicato in: eLife, Issue 9, 2020, ISSN 2050-084X
DOI: 10.7554/elife.54363

Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs

Autori: Jing Chen, Jonas Bacelis, Pol Sole-Navais, Amit Srivastava, Julius Juodakis, Amy Rouse, Mikko Hallman, Kari Teramo, Mads Melbye, Bjarke Feenstra, Rachel M. Freathy, George Davey Smith, Deborah A. Lawlor, Jeffrey C. Murray, Scott M. Williams, Bo Jacobsson, Louis J. Muglia, Ge Zhang
Pubblicato in: PLOS Medicine, Issue 17/8, 2020, Page(s) e1003305, ISSN 1549-1676
DOI: 10.1371/journal.pmed.1003305

Population reference and healthy standard blood pressure range charts in pregnancy: findings from the Born in Bradford cohort study

Autori: Gillian Santorelli, Debbie A. Lawlor, Jane West, Derek Tuffnell, Diane Farrar
Pubblicato in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
DOI: 10.1038/s41598-019-55324-2

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

Autori: Ralph McGinnis, Valgerdur Steinthorsdottir, Nicholas O Williams, Gudmar Thorleifsson, Scott Shooter, Sigrun Hjartardottir, Suzannah Bumpstead, Lilja Stefansdottir, Lucy Hildyard, Jon K Sigurdsson, John P Kemp, Gabriela B Silva, Liv Cecilie V Thomsen, Tiina Jääskeläinen, Eero Kajantie, Sally Chappell, Noor Kalsheker, Ashley Moffett, Susan Hiby, Wai Kwong Lee, Sandosh Padmanabhan, Nigel A B Simps
Pubblicato in: Nature Genetics, Issue 49/8, 2017, Page(s) 1255-1260, ISSN 1061-4036
DOI: 10.1038/ng.3895

Association of maternal exposures with adiposity at age 4/5 years in white British and Pakistani children: findings from the Born in Bradford study

Autori: Jane West, Gillian Santorelli, Peter H. Whincup, Lesley Smith, Naveed A. Sattar, Noel Cameron, Diane Farrar, Paul Collings, John Wright, Debbie A. Lawlor
Pubblicato in: Diabetologia, Issue 61/1, 2018, Page(s) 242-252, ISSN 0012-186X
DOI: 10.1007/s00125-017-4457-2

Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

Autori: Matias C. Vieira, Sara L. White, Nashita Patel, Paul T. Seed, Annette L. Briley, Jane Sandall, Paul Welsh, Naveed Sattar, Scott M. Nelson, Debbie A. Lawlor, Lucilla Poston, Dharmintra Pasupathy
Pubblicato in: BMC Medicine, Issue 15/1, 2017, ISSN 1741-7015
DOI: 10.1186/s12916-017-0956-8

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Autori: Robin N Beaumont, Nicole M Warrington, Alana Cavadino, Jessica Tyrrell, Michael Nodzenski, Momoko Horikoshi, Frank Geller, Ronny Myhre, Rebecca C Richmond, Lavinia Paternoster, Jonathan P Bradfield, Eskil Kreiner-Møller, Ville Huikari, Sarah Metrustry, Kathryn L Lunetta, Jodie N Painter, Jouke-Jan Hottenga, Catherine Allard, Sheila J Barton, Ana Espinosa, Julie A Marsh, Catherine Potter, Ge Zhang
Pubblicato in: Human Molecular Genetics, Issue 27/4, 2018, Page(s) 742-756, ISSN 0964-6906
DOI: 10.1093/hmg/ddx429

Maternal and fetal genetic contribution to gestational weight gain

Autori: N M Warrington, R Richmond, B Fenstra, R Myhre, R Gaillard, L Paternoster, C A Wang, R N Beaumont, S Das, M Murcia, S J Barton, A Espinosa, E Thiering, M Atalay, N Pitkänen, I Ntalla, A E Jonsson, R Freathy, V Karhunen, C M T Tiesler, C Allard, A Crawford, S M Ring, M Melbye, P Magnus, F Rivadeneira, L Skotte, T Hansen, J Marsh, M Guxens, J W Holloway, H Grallert, V W V Jaddoe, W L Lowe Jr, T Rou
Pubblicato in: International Journal of Obesity, Issue 42/4, 2017, Page(s) 775-784, ISSN 0307-0565
DOI: 10.1038/ijo.2017.248

Association of pre-pregnancy body mass index with offspring metabolic profile: Analyses of 3 European prospective birth cohorts

Autori: Diana L. Santos Ferreira, Dylan M. Williams, Antti J. Kangas, Pasi Soininen, Mika Ala-Korpela, George Davey Smith, Marjo-Riitta Jarvelin, Debbie A. Lawlor
Pubblicato in: PLOS Medicine, Issue 14/8, 2017, Page(s) e1002376, ISSN 1549-1676
DOI: 10.1371/journal.pmed.1002376

Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort

Autori: Judith S. Brand, Jane West, Derek Tuffnell, Philippa K. Bird, John Wright, Kate Tilling, Debbie A. Lawlor
Pubblicato in: BMC Medicine, Issue 16/1, 2018, ISSN 1741-7015
DOI: 10.1186/s12916-018-1191-7

Causal inference—so much more than statistics

Autori: Neil Pearce, Debbie A Lawlor
Pubblicato in: International Journal of Epidemiology, Issue 45/6, 2016, Page(s) 1895-1903, ISSN 0300-5771
DOI: 10.1093/ije/dyw328

Growing up in Bradford: protocol for the age 7–11 follow up of the Born in Bradford birth cohort

Autori: Philippa K Bird, Rosemary R. C. McEachan, Mark Mon-Williams, Neil Small, Jane West, Peter Whincup, John Wright, Elizabeth Andrews, Sally E Barber, Liam J B Hill, Laura Lennon, Dan Mason, Katy A Shire, Dagmar Waiblinger, Amanda H. Waterman, Deborah A. Lawlor, Kate E. Pickett
Pubblicato in: BMC Public Health, Issue 19/1, 2019, ISSN 1471-2458
DOI: 10.1186/s12889-019-7222-2

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

Autori: Christel M. Middeldorp, Janine F. Felix, Anubha Mahajan, Mark I. McCarthy
Pubblicato in: European Journal of Epidemiology, Issue 34/3, 2019, Page(s) 279-300, ISSN 0393-2990
DOI: 10.1007/s10654-019-00502-9

Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence

Autori: Qin Wang, Peter Würtz, Kirsi Auro, Laure Morin-Papunen, Antti J Kangas, Pasi Soininen, Mika Tiainen, Tuulia Tynkkynen, Anni Joensuu, Aki S Havulinna, Kristiina Aalto, Marko Salmi, Stefan Blankenberg, Tanja Zeller, Jorma Viikari, Mika Kähönen, Terho Lehtimäki, Veikko Salomaa, Sirpa Jalkanen, Marjo-Riitta Järvelin, Markus Perola, Olli T Raitakari, Debbie A Lawlor, Johannes Kettunen, Mika Ala-Ko
Pubblicato in: International Journal of Epidemiology, Issue 45/5, 2016, Page(s) 1445-1457, ISSN 0300-5771
DOI: 10.1093/ije/dyw147

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

Autori: Jessica Tyrrell, Rebecca C. Richmond, Tom M. Palmer, Bjarke Feenstra, Janani Rangarajan, Sarah Metrustry, Alana Cavadino, Lavinia Paternoster, Loren L. Armstrong, N. Maneka G. De Silva, Andrew R. Wood, Momoko Horikoshi, Frank Geller, Ronny Myhre, Jonathan P. Bradfield, Eskil Kreiner-Møller, Ville Huikari, Jodie N. Painter, Jouke-Jan Hottenga, Catherine Allard, Diane J. Berry, Luigi Bouchard, Shik
Pubblicato in: JAMA, Issue 315/11, 2016, Page(s) 1129, ISSN 0098-7484
DOI: 10.1001/jama.2016.1975

Metabolic signatures of birthweight in 18 288 adolescents and adults

Autori: Peter Würtz, Qin Wang, Marjo Niironen, Tuulia Tynkkynen, Mika Tiainen, Fotios Drenos, Antti J Kangas, Pasi Soininen, Michael R Skilton, Kauko Heikkilä, Anneli Pouta, Mika Kähönen, Terho Lehtimäki, Richard J Rose, Eero Kajantie, Markus Perola, Jaakko Kaprio, Johan G Eriksson, Olli T Raitakari, Debbie A Lawlor, George Davey Smith, Marjo-Riitta Järvelin, Mika Ala-Korpela, Kirsi Auro
Pubblicato in: International Journal of Epidemiology, Issue 45/5, 2016, Page(s) 1539-1550, ISSN 0300-5771
DOI: 10.1093/ije/dyw255

Triangulation in aetiological epidemiology

Autori: Debbie A. Lawlor, Kate Tilling, George Davey Smith
Pubblicato in: International Journal of Epidemiology, 2017, Page(s) dyw314, ISSN 0300-5771
DOI: 10.1093/ije/dyw314

Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence

Autori: Wang Q, Würtz P, Auro K, Kangas AJ, Soininen P, Tiainen M, Tynkkynen T, Jokelainen J, Santalahti K, Salmi M, Blankenberg S, Zeller T, Viikari J, Kähönen M, Lehtimäki T, Salomaa V, Perola M, Jalkanen S, Järvelin M-R, Raitakari OT, Kettunen J, Lawlor DA*, Ala-Korpela M* (*equal senior authors)
Pubblicato in: BMC Medicine, Issue 2016, 2016, Page(s) 205, ISSN 1741-7015
DOI: 10.1186/s12916-016-0733-0

Using genetic variation to explore the causal effect of maternal pregnancy adiposity on future offspring adiposity

Autori: Richmond RC, Timpson NJ, Felix JF, Palmer T, Gaillard R, McMahon G, Davey Smith G, Jaddoe VW, Lawlor DA
Pubblicato in: PloS Medicine, Issue 2017, 2017, Page(s) e1002221, ISSN 1549-1277
DOI: 10.1371/journal.pmed.1002221

Hyperglycaemia and risk of adverse perinatal outcomes: systematic review and meta-analysis

Autori: Diane Farrar, Mark Simmonds, Maria Bryant, Trevor A Sheldon, Derek Tuffnell, Su Golder, Fidelma Dunne, Debbie A Lawlor
Pubblicato in: BMJ, 2016, Page(s) i4694, ISSN 1756-1833
DOI: 10.1136/bmj.i4694

Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy

Autori: N Patel, K M Godfrey, D Pasupathy, J Levin, A C Flynn, L Hayes, A L Briley, R Bell, D A Lawlor, E Oteng-Ntim, S M Nelson, S C Robson, N Sattar, C Singh, J Wardle, S L White, P T Seed, L Poston
Pubblicato in: International Journal of Obesity, 2017, ISSN 0307-0565
DOI: 10.1038/ijo.2017.44

Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing them

Autori: Deborah Lawlor, Rebecca Richmond, Nicole Warrington, George McMahon, George Davey Smith, Jack Bowden, David M Evans
Pubblicato in: Wellcome Open Research, Issue 2, 2013, Page(s) 11, ISSN 2398-502X
DOI: 10.12688/wellcomeopenres.10567.1

Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania

Autori: Susana Santos, Iris Eekhout, Ellis Voerman, Romy Gaillard, Henrique Barros, Marie-Aline Charles, Leda Chatzi, Cécile Chevrier, George P. Chrousos, Eva Corpeleijn, Nathalie Costet, Sarah Crozier, Myriam Doyon, Merete Eggesbø, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Luigi Gagliardi, Vagelis Georgiu, Keith M. Godfrey, Davide Gori, Veit Grote, Wojciech Hanke, Irva Hertz-Picciotto, Barb
Pubblicato in: BMC Medicine, Issue 16/1, 2018, ISSN 1741-7015
DOI: 10.1186/s12916-018-1189-1

Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study

Autori: Maria C Magnus, Kozeta Miliku, Anna Bauer, Stephanie M Engel, Janine F Felix, Vincent W V Jaddoe, Debbie A Lawlor, Stephanie J London, Per Magnus, Ralph McGinnis, Wenche Nystad, Christian M Page, Fernando Rivadeneira, Lars C Stene, German Tapia, Nicholas Williams, Carolina Bonilla, Abigail Fraser
Pubblicato in: BMJ, Issue Maria C Magnus, Janine F Felix, Vincent W V Jaddoe, Per Magnus, 2018, Page(s) k2167, ISSN 0959-8138
DOI: 10.1136/bmj.k2167

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

Autori: Xueping Liu, Dorte Helenius, Line Skotte, Robin N. Beaumont, Matthias Wielscher, Frank Geller, Julius Juodakis, Anubha Mahajan, Jonathan P. Bradfield, Frederick T. J. Lin, Suzanne Vogelezang, Mariona Bustamante, Tarunveer S. Ahluwalia, Niina Pitkänen, Carol A. Wang, Jonas Bacelis, Maria C. Borges, Ge Zhang, Bruce A. Bedell, Robert M. Rossi, Kristin Skogstrand, Shouneng Peng, Wesley K. Thompson, V
Pubblicato in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-11881-8

Epigenetics and gestational diabetes: a review of epigenetic epidemiology studies and their use to explore epigenetic mediation and improve prediction

Autori: Hannah R. Elliott, Gemma C. Sharp, Caroline L. Relton, Deborah A. Lawlor
Pubblicato in: Diabetologia, Issue 62/12, 2019, Page(s) 2171-2178, ISSN 0012-186X
DOI: 10.1007/s00125-019-05011-8

Blood pressure change across pregnancy in white British and Pakistani women: analysis of data from the Born in Bradford cohort

Autori: Diane Farrar, Gillian Santorelli, Debbie A. Lawlor, Derek Tuffnell, Trevor A. Sheldon, Jane West, Corrie Macdonald-Wallis
Pubblicato in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
DOI: 10.1038/s41598-019-49722-9

Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight

Autori: Liang-Dar Hwang, Deborah A Lawlor, Rachel M Freathy, David M Evans, Nicole M Warrington
Pubblicato in: International Journal of Epidemiology, Issue 48/5, 2019, Page(s) 1457-1467, ISSN 0300-5771
DOI: 10.1093/ije/dyz160

A Cross‐Cohort Study Examining the Associations of Metabolomic Profile and Subclinical Atherosclerosis in Children and Their Parents: The Child Health CheckPoint Study and Avon Longitudinal Study of Parents and Children

Autori: Markus Juonala, Susan Ellul, Debbie A. Lawlor, Diana L. Santos Ferreira, John B. Carlin, Michael Cheung, Terence Dwyer, Melissa Wake, Richard Saffery, David P. Burgner
Pubblicato in: Journal of the American Heart Association, Issue 8/14, 2019, ISSN 2047-9980
DOI: 10.1161/jaha.118.011852

Paternal impact on the life course development of obesity and type 2 diabetes in the offspring

Autori: Gemma C. Sharp, Debbie A. Lawlor
Pubblicato in: Diabetologia, Issue 62/10, 2019, Page(s) 1802-1810, ISSN 0012-186X
DOI: 10.1007/s00125-019-4919-9

Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis

Autori: William D. Thompson, Jessica Tyrrell, Maria-Carolina Borges, Robin N. Beaumont, Bridget A. Knight, Andrew R. Wood, Susan M. Ring, Andrew T. Hattersley, Rachel M. Freathy, Debbie A. Lawlor
Pubblicato in: PLOS Medicine, Issue 16/6, 2019, Page(s) e1002828, ISSN 1549-1676
DOI: 10.1371/journal.pmed.1002828

Associations of maternal quitting, reducing, and continuing smoking during pregnancy with longitudinal fetal growth: Findings from Mendelian randomization and parental negative control studies

Autori: Judith S. Brand, Romy Gaillard, Jane West, Rosemary R. C. McEachan, John Wright, Ellis Voerman, Janine F. Felix, Kate Tilling, Deborah A. Lawlor
Pubblicato in: PLOS Medicine, Issue 16/11, 2019, Page(s) e1002972, ISSN 1549-1676
DOI: 10.1371/journal.pmed.1002972

Causal Inference in Environmental Epidemiology

Autori: Neil Pearce, Jan P. Vandenbroucke, Deborah A. Lawlor
Pubblicato in: Epidemiology, Issue 30/3, 2019, Page(s) 311-316, ISSN 1044-3983
DOI: 10.1097/ede.0000000000000987

4-Hydroxyglutamate is a novel predictor of pre-eclampsia

Autori: Ulla Sovio, Nancy McBride, Angela M Wood, Katya L Masconi, Emma Cook, Francesca Gaccioli, D Stephen Charnock-Jones, Debbie A Lawlor, Gordon C S Smith
Pubblicato in: International Journal of Epidemiology, Issue 49/1, 2019, Page(s) 301-311, ISSN 0300-5771
DOI: 10.1093/ije/dyz098

Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts

Autori: Tom A Bond, Ville Karhunen, Matthias Wielscher, Juha Auvinen, Minna Männikkö, Sirkka Keinänen-Kiukaanniemi, Marc J Gunter, Janine F Felix, Inga Prokopenko, Jian Yang, Peter M Visscher, David M Evans, Sylvain Sebert, Alex Lewin, Paul F O’Reilly, Debbie A Lawlor, Marjo-Riitta Jarvelin
Pubblicato in: International Journal of Epidemiology, Issue 49/1, 2019, Page(s) 233-243, ISSN 0300-5771
DOI: 10.1093/ije/dyz095

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

Autori: Nabila Kazmi, Gemma C. Sharp, Sarah E. Reese, Florianne O. Vehmeijer, Jari Lahti, Christian M. Page, Weiming Zhang, Sheryl L. Rifas-Shiman, Faisal I. Rezwan, Andrew J. Simpkin, Kimberley Burrows, Tom G. Richardson, Diana L. Santos Ferreira, Abigail Fraser, Quaker E. Harmon, Shanshan Zhao, Vincent W.V. Jaddoe, Darina Czamara, Elisabeth B. Binder, Maria C. Magnus, Siri E. Håberg, Wenche Nystad, Ell
Pubblicato in: Hypertension, Issue 74/2, 2019, Page(s) 375-383, ISSN 0194-911X
DOI: 10.1161/hypertensionaha.119.12634

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Autori: Nicole M. Warrington, Robin N. Beaumont, Momoko Horikoshi, Felix R. Day, Øyvind Helgeland, Charles Laurin, Jonas Bacelis, Shouneng Peng, Ke Hao, Bjarke Feenstra, Andrew R. Wood, Anubha Mahajan, Jessica Tyrrell, Neil R. Robertson, N. William Rayner, Zhen Qiao, Gunn-Helen Moen, Marc Vaudel, Carmen J. Marsit, Jia Chen, Michael Nodzenski, Theresia M. Schnurr, Mohammad H. Zafarmand, Jonathan P. Bradfi
Pubblicato in: Nature Genetics, Issue 51/5, 2019, Page(s) 804-814, ISSN 1061-4036
DOI: 10.1038/s41588-019-0403-1

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Autori: Leanne K. Küpers, Claire Monnereau, Gemma C. Sharp, Paul Yousefi, Lucas A. Salas, Akram Ghantous, Christian M. Page, Sarah E. Reese, Allen J. Wilcox, Darina Czamara, Anne P. Starling, Alexei Novoloaca, Samantha Lent, Ritu Roy, Cathrine Hoyo, Carrie V. Breton, Catherine Allard, Allan C. Just, Kelly M. Bakulski, John W. Holloway, Todd M. Everson, Cheng-Jian Xu, Rae-Chi Huang, Diana A. van der Plaat
Pubblicato in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-09671-3

Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes

Autori: Ellis Voerman, Susana Santos, Hazel Inskip, Pilar Amiano, Henrique Barros, Marie-Aline Charles, Leda Chatzi, George P. Chrousos, Eva Corpeleijn, Sarah Crozier, Myriam Doyon, Merete Eggesbø, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Vagelis Georgiu, Davide Gori, Wojciech Hanke, Irva Hertz-Picciotto, Barbara Heude, Marie-France Hivert, Daniel Hryhorczuk, Carmen Iñiguez, Anne M. Karvone
Pubblicato in: JAMA, Issue 321/17, 2019, Page(s) 1702, ISSN 0098-7484
DOI: 10.1001/jama.2019.3820

The effect of a lifestyle intervention in obese pregnant women on gestational metabolic profiles: findings from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) randomised controlled trial

Autori: Harriet L. Mills, Nashita Patel, Sara L. White, Dharmintra Pasupathy, Annette L. Briley, Diana L. Santos Ferreira, Paul T. Seed, Scott M. Nelson, Naveed Sattar, Kate Tilling, Lucilla Poston, Deborah A. Lawlor
Pubblicato in: BMC Medicine, Issue 17/1, 2019, ISSN 1741-7015
DOI: 10.1186/s12916-018-1248-7

Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization

Autori: David M Evans, Gunn-Helen Moen, Liang-Dar Hwang, Debbie A Lawlor, Nicole M Warrington
Pubblicato in: International Journal of Epidemiology, Issue 48/3, 2019, Page(s) 861-875, ISSN 0300-5771
DOI: 10.1093/ije/dyz019

It's the mother!: How assumptions about the causal primacy of maternal effects influence research on the developmental origins of health and disease

Autori: Gemma C. Sharp, Deborah A. Lawlor, Sarah S. Richardson
Pubblicato in: Social Science & Medicine, Issue 213, 2018, Page(s) 20-27, ISSN 0277-9536
DOI: 10.1016/j.socscimed.2018.07.035

Prevalence of Prenatal Depression Symptoms Among 2 Generations of Pregnant Mothers

Autori: Rebecca M. Pearson, Rebecca E. Carnegie, Callum Cree, Claire Rollings, Louise Rena-Jones, Jonathan Evans, Alan Stein, Kate Tilling, Melanie Lewcock, Debbie A. Lawlor
Pubblicato in: JAMA Network Open, Issue 1/3, 2018, Page(s) e180725, ISSN 2574-3805
DOI: 10.1001/jamanetworkopen.2018.0725

Associations of social and economic and pregnancy exposures with blood pressure in UK White British and Pakistani children age 4/5

Autori: Jane West, Debbie A. Lawlor, Gillian Santorelli, Paul Collings, Peter H. Whincup, Naveed A. Sattar, Diane Farrar, John Wright
Pubblicato in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-27316-1

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

Autori: Simon Kebede Merid, Alexei Novoloaca, Gemma C. Sharp, Leanne K. Küpers, Alvin T. Kho, Ritu Roy, Lu Gao, Isabella Annesi-Maesano, Pooja Jain, Michelle Plusquin, Manolis Kogevinas, Catherine Allard, Florianne O. Vehmeijer, Nabila Kazmi, Lucas A. Salas, Faisal I. Rezwan, Hongmei Zhang, Sylvain Sebert, Darina Czamara, Sheryl L. Rifas-Shiman, Phillip E. Melton, Debbie A. Lawlor, Göran Pershagen, Carr
Pubblicato in: Genome Medicine, Issue 12/1, 2020, ISSN 1756-994X
DOI: 10.1186/s13073-020-0716-9

GLU, a software package for analysing continuously measured glucose levels in epidemiology

Autori: Louise A C Millard, Nashita Patel, Kate Tilling, Melanie Lewcock, Peter A Flach, Debbie A Lawlor
Pubblicato in: International Journal of Epidemiology, 2020, ISSN 0300-5771
DOI: 10.1093/ije/dyaa004

A maternal serum metabolite ratio predicts fetal growth restriction at term

Autori: Ulla Sovio, Neil Goulding, Nancy McBride, Emma Cook, Francesca Gaccioli, D. Stephen Charnock-Jones, Debbie A. Lawlor, Gordon C. S. Smith
Pubblicato in: Nature Medicine, Issue 26/3, 2020, Page(s) 348-353, ISSN 1078-8956
DOI: 10.1038/s41591-020-0804-9

Metabolic phenotyping by treatment modality in obese women with gestational diabetes suggests diverse pathophysiology: An exploratory study

Autori: Sara L. White, Shahina Begum, Matias C. Vieira, Paul Seed, Deborah L. Lawlor, Naveed Sattar, Scott M. Nelson, Paul Welsh, Dharmintra Pasupathy, Lucilla Poston
Pubblicato in: PLOS ONE, Issue 15/4, 2020, Page(s) e0230658, ISSN 1932-6203
DOI: 10.1371/journal.pone.0230658

UK stillbirth trends in over 11 million births provide no evidence to support effectiveness of Growth Assessment Protocol program

Autori: S. Iliodromiti, G. C. S. Smith, D. A. Lawlor, J. P. Pell, S. M. Nelson
Pubblicato in: Ultrasound in Obstetrics & Gynecology, Issue 55/5, 2020, Page(s) 599-604, ISSN 0960-7692
DOI: 10.1002/uog.21999

Association of the serum metabolomic profile by nuclear magnetic resonance spectroscopy with sperm parameters: a cross-sectional study of 325 men

Autori: Karema Al Rashid, Amy Taylor, Mary Ann Lumsden, Neil Goulding, Deborah A. Lawlor, Scott M. Nelson
Pubblicato in: F&S Science, Issue 1/2, 2020, Page(s) 142-160, ISSN 2666-335X
DOI: 10.1016/j.xfss.2020.10.003

Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile

Autori: William D. Thompson, Robin N. Beaumont, Alan Kuang, Nicole M. Warrington, Yingjie Ji, Jessica Tyrrell, Andrew R. Wood, Denise M. Scholtens, Bridget A. Knight, David M. Evans, William L. Lowe, Gillian Santorelli, Rafaq Azad, Dan Mason, Andrew T. Hattersley, Timothy M. Frayling, Hanieh Yaghootkar, Maria Carolina Borges, Deborah A. Lawlor, Rachel M. Freathy
Pubblicato in: Diabetologia, 2021, ISSN 0012-186X
DOI: 10.1007/s00125-021-05570-9

The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies.

Autori: Yu, Bing; Zanetti, Krista A; Temprosa, Marinella; Albanes, Demetrius; Appel, Nathan; Barrera, Clara Barrios; Ben-Shlomo, Yoav; Boerwinkle, Eric; Casas, Juan P; Clish, Clary; Dale, Caroline; Dehghan, Abbas; Derkach, Andriy; Eliassen, A Heather; Elliott, Paul; Fahy, Eoin; Gieger, Christian; Gunter, Marc J; Harada, Sei; Harris, Tamara; Herr, Deron R; Herrington, David; Hirschhorn, Joel N; Hoover, Eli
Pubblicato in: American Journal of Epidemiology, Issue 1, 2019, Page(s) 991-1012, ISSN 0002-9262
DOI: 10.1093/aje/kwz028

Differences in Pregnancy Metabolic Profiles and Their Determinants between White European and South Asian Women: Findings from the Born in Bradford Cohort

Autori: Kurt Taylor, Diana L Santos Ferreira, Jane West, Tiffany Yang, Massimo Caputo, Deborah A Lawlor
Pubblicato in: Metabolites, 2019, ISSN 2218-1989
DOI: 10.3390/metabo9090190

The second generation of The Avon Longitudinal Study of Parents and Children (ALSPAC-G2): a cohort profile

Autori: Deborah A. Lawlor, Melanie Lewcock, Louise Rena-Jones, Claire Rollings, Vikki Yip, Daniel Smith, Rebecca M. Pearson, Laura Johnson, Louise A. C. Millard, Nashita Patel, Andy Skinner, Kate Tilling
Pubblicato in: Wellcome Open Research, Issue 4, 2019, Page(s) 36, ISSN 2398-502X
DOI: 10.12688/wellcomeopenres.15087.1

Set di dati

Additional file 1 of Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses

Autori: Bos, Maxime M.; Goulding, Neil J.; Lee, Matthew A.; Hofman, Amy; Bot, Mariska; Pool, René; Vijfhuizen, Lisanne S.; Zhang, Xiang; Chihua Li; Mustafa, Rima; Neville, Matt J.; Ruifang Li-Gao; Trompet, Stella; Beekman, Marian; Biermasz, Nienke R.; Dorret I. Boomsma; Boer, Irene De; Constantinos Christodoulides; Dehghan, Abbas; Dijk, Ko Willems Van; Ford, Ian; Ghanbari, Mohsen; Heijmans, Bastiaan T.; M. Arfan Ikram; J. Wouter Jukema; Mook-Kanamori, Dennis O.; Karpe, Fredrik; Luik, Annemarie I.; L. H. Lumey; Maagdenberg, Arn M. J. M. Van Den; Mooijaart, Simon P.; Mutsert, Renée De; Penninx, Brenda W. J. H.; Rensen, Patrick C. N.; Richmond, Rebecca C.; Rosendaal, Frits R.; Sattar, Naveed; Schoevers, Robert A.; P. Eline Slagboom; Terwindt, Gisela M.; Carisha S. Thesing; Wade, Kaitlin H.; Wijsman, Carolien A.; Willemsen, Gonneke; Aeilko H. Zwinderman; Heemst, Diana Van; Noordam, Raymond; Lawlor, Deborah A.
Pubblicato in: figshare

Additional file 1 of Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

Autori: Merid, Simon; Novoloaca, Alexei; Sharp, Gemma; Küpers, Leanne; Kho, Alvin; Roy, Ritu; Gao, Lu; Annesi-Maesano, Isabella; Jain, Pooja; Plusquin, Michelle; Kogevinas, Manolis; Allard, Catherine; Vehmeijer, Florianne; Kazmi, Nabila; Salas, Lucas; Rezwan, Faisal; Hongmei Zhang; Sebert, Sylvain; Czamara, Darina; Rifas-Shiman, Sheryl; Melton, Phillip; Lawlor, Debbie; Pershagen, Göran; Breton, Carrie; Huen, Karen; Baiz, Nour; Gagliardi, Luigi; Nawrot, Tim; Corpeleijn, Eva; Perron, Patrice; Duijts, Liesbeth; Nohr, Ellen; Mariona Bustamante; Ewart, Susan; Karmaus, Wilfried; Shanshan Zhao; Page, Christian; Herceg, Zdenko; Marjo-Riitta Jarvelin; Lahti, Jari; Baccarelli, Andrea; Anderson, Denise; Priyadarshini Kachroo; Relton, Caroline; Bergström, Anna; Eskenazi, Brenda; Soomro, Munawar; Vineis, Paolo; Snieder, Harold; Bouchard, Luigi; Jaddoe, Vincent; Sørensen, Thorkild; Vrijheid, Martine; S. Arshad; Holloway, John; Håberg, Siri; Magnus, Per; Dwyer, Terence; Binder, Elisabeth; DeMeo, Dawn; Vonk, Judith; Newnham, John; Kelan Tantisira; Kull, Inger; Wiemels, Joseph; Heude, Barbara; Sunyer, Jordi; Nystad, Wenche; Munthe-Kaas, Monica; Räikkönen, Katri; Oken, Emily; Rae-Chi Huang; Weiss, Scott; Antó, Josep; Bousquet, Jean; Kumar, Ashish; Söderhäll, Cilla; Almqvist, Catarina; Cardenas, Andres; Gruzieva, Olena; Xu, Cheng-Jian; Reese, Sarah; Kere, Juha; Brodin, Petter; Solomon, Olivia; Wielscher, Matthias; Holland, Nina; Ghantous, Akram; Marie-France Hivert; Felix, Janine; Koppelman, Gerard; London, Stephanie; Melén, Erik
Pubblicato in: figshare

Additional file 2: of The effect of a lifestyle intervention in obese pregnant women on gestational metabolic profiles: findings from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) randomised controlled trial

Autori: Mills, Harriet; Nashita Patel; White, Sara; Dharmintra Pasupathy; Briley, Annette; Ferreira, Diana Santos; Seed, Paul; Nelson, Scott; Sattar, Naveed; Tilling, Kate; Poston, Lucilla; Lawlor, Deborah
Pubblicato in: figshare

Additional file 2 of Identifying potential causal effects of age at menarche: a Mendelian randomization phenome-wide association study

Autori: Magnus, Maria C.; Guyatt, Anna L.; Lawn, Rebecca B.; Annah B. Wyss; Trajanoska, Katerina; Küpers, Leanne K.; Rivadeneira, Fernando; Tobin, Martin D.; London, Stephanie J.; Lawlor, Debbie A.; Millard, Louise A. C.; Fraser, Abigail
Pubblicato in: figshare

Additional file 3 of Identifying potential causal effects of age at menarche: a Mendelian randomization phenome-wide association study

Autori: Magnus, Maria C.; Guyatt, Anna L.; Lawn, Rebecca B.; Annah B. Wyss; Trajanoska, Katerina; Küpers, Leanne K.; Rivadeneira, Fernando; Tobin, Martin D.; London, Stephanie J.; Lawlor, Debbie A.; Millard, Louise A. C.; Fraser, Abigail
Pubblicato in: figshare