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HIV-1 sensing and signaling in dendritic cells

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Publications

MAVS Genetic Variation Is Associated with Decreased HIV-1 Replication In Vitro and Reduced CD4+ T Cell Infection in HIV-1-Infected Individuals

Author(s): Melissa Stunnenberg, Lisa van Pul, Joris K. Sprokholt, Karel A. van Dort, Sonja I. Gringhuis, Teunis B. H. Geijtenbeek, Neeltje A. Kootstra
Published in: Viruses, 12/7, 2020, Page(s) 764, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v12070764

Separate signaling events control TCR downregulation and T cell activation in primary human T cells

Author(s): Lieve E. H. Donk, Louis S. Ates, Jet Spek, Laura M. Tukker, Teunis B. H. Geijtenbeek, Jeroen W. J. Heijst
Published in: Immunity, Inflammation and Disease, 9/1, 2021, Page(s) 223-238, ISSN 2050-4527
Publisher: Wiley
DOI: 10.1002/iid3.383

RIG-I–like Receptor Triggering by Dengue Virus Drives Dendritic Cell Immune Activation and T H 1 Differentiation

Author(s): Joris K. Sprokholt, Tanja M. Kaptein, John L. van Hamme, Ronald J. Overmars, Sonja I. Gringhuis, Teunis B. H. Geijtenbeek
Published in: The Journal of Immunology, 198/12, 2017, Page(s) 4764-4771, ISSN 0022-1767
Publisher: American Association of Immunologists
DOI: 10.4049/jimmunol.1602121

DDX3 in HIV-1 infection and sensing: A paradox

Author(s): Melissa Stunnenberg, Teunis B.H. Geijtenbeek, Sonja I. Gringhuis
Published in: Cytokine & Growth Factor Reviews, 40, 2018, Page(s) 32-39, ISSN 1359-6101
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.cytogfr.2018.03.001

C-Type Lectin Receptors in Antiviral Immunity and Viral Escape

Author(s): Marta Bermejo-Jambrina, Julia Eder, Leanne C. Helgers, Nina Hertoghs, Bernadien M. Nijmeijer, Melissa Stunnenberg, Teunis B. H. Geijtenbeek
Published in: Frontiers in Immunology, 9, 2018, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2018.00590

RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production

Author(s): Joris K. Sprokholt, Tanja M. Kaptein, John L. van Hamme, Ronald J. Overmars, Sonja I. Gringhuis, Teunis B. H. Geijtenbeek
Published in: PLOS Pathogens, 13/11, 2017, Page(s) e1006738, ISSN 1553-7374
Publisher: PLOS
DOI: 10.1371/journal.ppat.1006738

DCs facilitate B cell responses against microbial DNA via DC-SIGN

Author(s): Joris K. Sprokholt, Marieke H. Heineke, Tanja M. Kaptein, John L. van Hamme, Teunis B. H. Geijtenbeek
Published in: PLOS ONE, 12/10, 2017, Page(s) e0185580, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0185580

C-type lectin receptors in the control of T helper cell differentiation

Author(s): Teunis B. H. Geijtenbeek, Sonja I. Gringhuis
Published in: Nature Reviews Immunology, 16/7, 2016, Page(s) 433-448, ISSN 1474-1733
Publisher: Nature Publishing Group
DOI: 10.1038/nri.2016.55

Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets

Author(s): Carla M. S. Ribeiro, Ramin Sarrami-Forooshani, Laurentia C. Setiawan, Esther M. Zijlstra-Willems, John L. van Hamme, Wikky Tigchelaar, Nicole N. van der Wel, Neeltje A. Kootstra, Sonja I. Gringhuis, Teunis B. H. Geijtenbeek
Published in: Nature, 540/7633, 2016, Page(s) 448-452, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature20567

Interplay between HIV-1 innate sensing and restriction in mucosal dendritic cells: balancing defense and viral transmission

Author(s): Nina Hertoghs, Teunis B.H. Geijtenbeek, Carla M.S. Ribeiro
Published in: Current Opinion in Virology, 22, 2017, Page(s) 112-119, ISSN 1879-6257
Publisher: Elsevier BV
DOI: 10.1016/j.coviro.2017.01.001

HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3

Author(s): Sonja I Gringhuis, Nina Hertoghs, Tanja M Kaptein, Esther M Zijlstra-Willems, Ramin Sarrami-Fooroshani, Joris K Sprokholt, Nienke H van Teijlingen, Neeltje A Kootstra, Thijs Booiman, Karel A van Dort, Carla M S Ribeiro, Agata Drewniak, Teunis B H Geijtenbeek
Published in: Nature Immunology, 18/2, 2016, Page(s) 225-235, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/ni.3647

Syndecan 4 Upregulation on Activated Langerhans Cells Counteracts Langerin Restriction to Facilitate Hepatitis C Virus Transmission

Author(s): Bernadien M. Nijmeijer, Julia Eder, Catharina J. M. Langedijk, Tanja M. Kaptein, Sofie Meeussen, Pascale Zimmermann, Carla M. S. Ribeiro, Teunis B. H. Geijtenbeek
Published in: Frontiers in Immunology, 11, 2020, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2020.00503

Various Tastes of Sugar: The Potential of Glycosylation in Targeting and Modulating Human Immunity via C-Type Lectin Receptors

Author(s): Stefanie Busold, Noémi A. Nagy, Sander W. Tas, Ronald van Ree, Esther C. de Jong, Teunis B. H. Geijtenbeek
Published in: Frontiers in Immunology, 11, 2020, ISSN 1664-3224
Publisher: frontiers
DOI: 10.3389/fimmu.2020.00134

Synthetic Abortive HIV-1 RNAs Induce Potent Antiviral Immunity

Author(s): Melissa Stunnenberg, Joris K. Sprokholt, John L. van Hamme, Tanja M. Kaptein, Esther M. Zijlstra-Willems, Sonja I. Gringhuis, Teunis B. H. Geijtenbeek
Published in: Frontiers in Immunology, 11, 2020, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2020.00008

Vaginal dysbiosis associated-bacteria Megasphaera elsdenii and Prevotella timonensis induce immune activation via dendritic cells

Author(s): Nienke H. van Teijlingen, Leanne C. Helgers, Esther M. Zijlstra - Willems, John L. van Hamme, Carla M.S. Ribeiro, Karin Strijbis, Teunis B.H. Geijtenbeek
Published in: Journal of Reproductive Immunology, 138, 2020, Page(s) 103085, ISSN 0165-0378
Publisher: Elsevier BV
DOI: 10.1016/j.jri.2020.103085

Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction

Author(s): Nina Hertoghs, Bernadien M. Nijmeijer, Nienke H. van Teijlingen, Angharad E. Fenton-May, Tanja M. Kaptein, John L. van Hamme, John C. Kappes, Neeltje A. Kootstra, Beatrice H. Hahn, Persephone Borrow, Carla M. S. Ribeiro, Teunis B. H. Geijtenbeek
Published in: PLOS ONE, 14/12, 2019, Page(s) e0226651, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0226651

Borrelia miyamotoi Activates Human Dendritic Cells and Elicits T Cell Responses

Author(s): Lauren M. K. Mason, Joris Koetsveld, Jos J. A. Trentelman, Tanja M. Kaptein, Dieuwertje Hoornstra, Alex Wagemakers, Michelle M. Fikrig, Jasmin I. Ersoz, Anneke Oei, Teunis B. H. Geijtenbeek, Joppe W. R. Hovius
Published in: The Journal of Immunology, 204/2, 2020, Page(s) 386-393, ISSN 0022-1767
Publisher: American Association of Immunologists
DOI: 10.4049/jimmunol.1801589

Sexually transmitted hepatitis C virus infections: current trends, and recent advances in understanding the spread in men who have sex with men

Author(s): Bernadien M Nijmeijer, Jelle Koopsen, Janke Schinkel, Maria Prins, Teunis BH Geijtenbeek
Published in: Journal of the International AIDS Society, 22/S6, 2019, ISSN 1758-2652
Publisher: International AIDS Society
DOI: 10.1002/jia2.25348

Negative and Positive Selection Pressure During Sexual Transmission of Transmitted Founder HIV-1

Author(s): Bernadien M. Nijmeijer, Teunis B. H. Geijtenbeek
Published in: Frontiers in Immunology, 10, 2019, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2019.01599

HIV ‐1 exposure and immune activation enhance sexual transmission of Hepatitis C virus by primary Langerhans cells

Author(s): Bernadien M Nijmeijer, Ramin Sarrami‐Forooshani, Gaby S Steba, Renée RCE Schreurs, Sylvie M Koekkoek, Richard Molenkamp, Janke Schinkel, Peter Reiss, Matthijs L Siegenbeek van Heukelom, Marc Valk, Carla MS Ribeiro, Teunis BH Geijtenbeek
Published in: Journal of the International AIDS Society, 22/3, 2019, Page(s) e25268, ISSN 1758-2652
Publisher: International AIDS Society
DOI: 10.1002/jia2.25268

Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life

Author(s): Renée R.C.E. Schreurs, Martin E. Baumdick, Adrian F. Sagebiel, Max Kaufmann, Michal Mokry, Paul L. Klarenbeek, Nicola Schaltenberg, Fenja L. Steinert, Jorik M. van Rijn, Agata Drewniak, Sarah-May M.L. The, Roel Bakx, Joep P.M. Derikx, Niek de Vries, Willemijn E. Corpeleijn, Steven T. Pals, Nicola Gagliani, Manuel A. Friese, Sabine Middendorp, Edward E.S. Nieuwenhuis, Konrad Reinshagen, Teunis B.H
Published in: Immunity, 50/2, 2019, Page(s) 462-476.e8, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2018.12.010

Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22–Specific Th Cells

Author(s): Yohei Otsuka, Eri Watanabe, Eiji Shinya, Sadayuki Okura, Hidehisa Saeki, Teunis B. H. Geijtenbeek, Hidemi Takahashi
Published in: The Journal of Immunology, 201/10, 2018, Page(s) 3006-3016, ISSN 0022-1767
Publisher: American Association of Immunologists
DOI: 10.4049/jimmunol.1701402