Objective MAST4HEALTH is set on the concept of a multidisciplinary approach to assess a non-pharmacological intervention for managing NAFLD/NASH, one of the most common complications of obesity and diabetes mellitus in Western populations affecting approximately 50% of diabetics and 76% of obese patients. Because of limitations in current NAFLD treatment therapies, many new efforts focus on exploring non-pharmacologic means for managing the disease and in particular through dietary substances or bioactive phytochemicals in fruits, vegetables, and plants or their products. MAST4HEALTH aims at exploring the effect of Mastiha, a natural product of Greece which was recently shown to possess antioxidant/anti-inflammatory and lipid lowering properties. We designed a multicenter randomized double blind placebo controlled (parallel arm) clinical trial to test the effectiveness of Mastiha supplement as new non-pharmacologic strategy for NAFLD/NASH treatment. MAST4HEALTH will explore gene-diet interactions, more specifically the potential personalized activity of the Mastiha, and correlate genetic and epigenetic markers with metabolomic and intestinal microbiota profiles pre- and post-intervention. The effectiveness of the proposed intervention will be evaluated via clinical and laboratory markers of the disease. To this end, MAST4HEALTH will train a number of researchers and PhD students in multidisciplinary approaches of this survey. MAST4HEALTH is expected to build and enhance cooperation among partners meanwhile strengthening the interaction between our academic and non-academic sectors Fields of science medical and health scienceshealth sciencespublic healthmedical and health sciencesclinical medicineendocrinologydiabetesagricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturevegetable growingmedical and health sciencesclinical medicinehepatologymedical and health scienceshealth sciencesnutritionobesity Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge Topic(s) MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Call for proposal H2020-MSCA-RISE-2015 See other projects for this call Funding Scheme MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Coordinator CHAROKOPEIO PANEPISTIMIO Net EU contribution € 441 000,00 Address ELEFTHERIOU VENIZELOU 70 176 71 ATHINA Greece See on map Region Αττική Aττική Νότιος Τομέας Αθηνών Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 441 000,00 Participants (14) Sort alphabetically Sort by Net EU contribution Expand all Collapse all QUEEN MARY UNIVERSITY OF LONDON United Kingdom Net EU contribution € 162 000,00 Address 327 MILE END ROAD E1 4NS London See on map Region London Inner London — East Tower Hamlets Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 162 000,00 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France Net EU contribution € 135 000,00 Address RUE DE TOLBIAC 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 135 000,00 CONSIGLIO NAZIONALE DELLE RICERCHE Italy Net EU contribution € 121 500,00 Address PIAZZALE ALDO MORO 7 00185 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 121 500,00 FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA Spain Net EU contribution € 117 000,00 Address CALLE MICER MASCO 31 46010 Valencia See on map Region Este Comunitat Valenciana Valencia/València Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 117 000,00 BIOTECH VANA SL Spain Net EU contribution € 157 500,00 Address CALLE CATEDRATICO AGUSTIN ESCARDINO 9, EDIFICIO 1.17, VIVERO PARC CIENTIFIC DE LA UNIVERSITAT DE VALENCIA 46980 PATERNA (VALENCIA) See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Este Comunitat Valenciana Valencia/València Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 157 500,00 Randox Laboratories Ltd United Kingdom Net EU contribution € 153 000,00 Address Diamond Road 55 BT29 4QY Crumlin See on map Region Northern Ireland Northern Ireland Antrim and Newtownabbey Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 153 000,00 MARASCIO FERNANDO Italy Net EU contribution € 108 000,00 Address See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 108 000,00 SANOFI-AVENTIS DEUTSCHLAND GMBH Germany Net EU contribution € 81 000,00 Address BRUNINGSTRASSE 50 65929 Frankfurt Am Main See on map Region Hessen Darmstadt Frankfurt am Main, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 81 000,00 ENOSIS MASTICHOPARAGOGON CHIOU Greece Net EU contribution € 297 000,00 Address 1 K. MONOMACHOU ST 82100 Chios See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Νησιά Αιγαίου Βόρειο Αιγαίο Χίος Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 297 000,00 PERSPECTUM LTD United Kingdom Net EU contribution € 157 500,00 Address GEMINI ONE, 5520 JOHN SMITH DRIVE OXFORD BUSINESS PARK SOUTH OX4 2LL Oxford See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 157 500,00 UNIVERSITY OF NOVI SAD, FACULTY OF MEDICINE NOVI SAD Serbia Net EU contribution € 108 000,00 Address HAJDUK VELJKOVA STREET 3 21000 Novi Sad See on map Region Србија - север Регион Војводине Јужнобачка област Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 108 000,00 UNIVERZITET U ISTOCNOM SARAJEVU Bosnia and Herzegovina Net EU contribution € 13 500,00 Address VUKA KARADZICA 30 71123 Istocno Sarajevo See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 13 500,00 UNIVERSITA DEGLI STUDI DI MILANO Italy Net EU contribution € 63 000,00 Address Via Festa Del Perdono 7 20122 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 63 000,00 FONDAZIONE IRCCS CA' GRANDA - OSPEDALE MAGGIORE POLICLINICO Italy Net EU contribution € 9 000,00 Address VIA FRANCESCO SFORZA 28 20122 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Other Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 9 000,00
