Custom architecturally defined 3D stem cell derived functional human neural networks for transformative progress in neuroscience and medicine

Deliverables

Websites, patent fillings, videos etc. (5)

Use and Dissemination 3

Plan for Use and Dissemination

Website Development

Web-site developed and brand established;

Press Releases

Initial National and European press releases

Use and Dissemination 2

Plan for Use and Dissemination

Use and Dissemination 1

Plan for Use and Dissemination

Documents, reports (6)

Tools for functional connectivity analysis 2

Tools for functional connectivity analysis 2

Imaging with fast 3D imaging of neuron activity

Imaging with fast 3D imaging of neuron activity

Light sheet microscope for fast 3D imaging of neuron activity II

Light sheet microscope for fast 3D imaging of neuron activity II

Optimal imaging conditions

Optimal imaging conditions

Tools for functional connectivity analysis 1

Tools for functional connectivity analysis 1

Light sheet microscope for fast 3D imaging of neuron activity I

Light sheet microscope for fast 3D imaging of neuron activity I

Demonstrators, pilots, prototypes (1)

Physiological chamber

Physiological chamber

Publications

Peer reviewed articles (8)

The Photobiomodulation of Vital Parameters of the Cancer Cell Culture by Low Dose of Near-IR Laser Irradiation

Author(s): Anna Khokhlova, Igor Zolotovskii, Dmitrii Stoliarov, Svetlana Vorsina, Daria Liamina, Evgenia Pogodina, Andrei A. Fotiadi, Sergei G. Sokolovski, Yury Saenko, Edik U. Rafailov
Published in: IEEE Journal of Selected Topics in Quantum Electronics, 25/1, 2019, Page(s) 1-10, ISSN 1077-260X
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/jstqe.2018.2854539

Impact of modular organization on dynamical richness in cortical networks

Author(s): Hideaki Yamamoto, Satoshi Moriya, Katsuya Ide, Takeshi Hayakawa, Hisanao Akima, Shigeo Sato, Shigeru Kubota, Takashi Tanii, Michio Niwano, Sara Teller, Jordi Soriano, Ayumi Hirano-Iwata
Published in: Science Advances, 4/11, 2018, Page(s) eaau4914, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aau4914

CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons

Author(s): Carles Calatayud, Giulia Carola, Irene Fernández-Carasa, Marco Valtorta, Senda Jiménez-Delgado, Mònica Díaz, Jordi Soriano-Fradera, Graziella Cappelletti, Javier García-Sancho, Ángel Raya, Antonella Consiglio
Published in: Scientific Reports, 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-43080-2

Photodynamic opening of blood-brain barrier

Author(s): Oxana Semyachkina-Glushkovskaya, Jürgen Kurths, Ekaterina Borisova, Sergei Sokolovski, Vanya Mantareva, Ivan Angelov, Alexander Shirokov, Nikita Navolokin, Natalia Shushunova, Alexander Khorovodov, Maria Ulanova, Madina Sagatova, Ilana Agranivich, Olga Sindeeva, Artem Gekalyuk, Anastasiya Bodrova, and Edik Rafailov
Published in: Biomedical Optics Express, 2017, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.8.005040

Neuronal spatial arrangement shapes effective connectivity traits of in vitro cortical networks

Author(s): Elisenda Tibau Martorell, Adriaan Alexander Ludl, Sten Rudiger, Javier G. Orlandi, Jordi Soriano
Published in: IEEE Transactions on Network Science and Engineering, 2017, Page(s) 1-1, ISSN 2327-4697
Publisher: IEEE Computer Society
DOI: 10.1109/tnse.2018.2862919

7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington’s disease mouse model through specific activation of the PLCγ1 pathway

Author(s): Gerardo García-Díaz Barriga, Albert Giralt, Marta Anglada-Huguet, Nuria Gaja-Capdevila, Javier G. Orlandi, Jordi Soriano, Josep-Maria Canals, Jordi Alberch
Published in: Human Molecular Genetics, Vol26, No 16, 2017, Page(s) 3144–3160, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddx198

STED imaging performance estimation by means of Fourier transform analysis

Author(s): David Merino, Arrate Mallabiabarrena, Jordi Andilla, David Artigas, Timo Zimmermann, Pablo Loza-Alvarez
Published in: Biomedical Optics Express, 8/5, 2017, Page(s) 2472, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/BOE.8.002472

Sub-diffraction discrimination with polarization-resolved two-photon excited fluorescence microscopy

Author(s): David Artigas, David Merino, Christoph Polzer, Pablo Loza-Alvarez
Published in: Optica, 4/8, 2017, Page(s) 911, ISSN 2334-2536
Publisher: OSA Publishing
DOI: 10.1364/optica.4.000911