Custom architecturally defined 3D stem cell derived functional human neural networks for transformative progress in neuroscience and medicine

Informazioni relative al progetto

MESO_BRAIN

ID dell’accordo di sovvenzione: 713140

DOI

10.3030/713140

Progetto chiuso

Data della firma CE 25 Maggio 2016

Data di avvio 1 Settembre 2016

Data di completamento 29 Febbraio 2020

Finanziato da

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Costo totale

€ 3 225 891,25

Contributo UE

€ 3 225 890,50

Coordinato da

ASTON UNIVERSITY
United Kingdom

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Websites, patent fillings, videos etc. (5)

Use and Dissemination 3

Plan for Use and Dissemination

Website Development

Web-site developed and brand established;

Press Releases

Initial National and European press releases

Use and Dissemination 2

Plan for Use and Dissemination

Use and Dissemination 1

Plan for Use and Dissemination

Documents, reports (6)

Tools for functional connectivity analysis 2
Imaging with fast 3D imaging of neuron activity
Light sheet microscope for fast 3D imaging of neuron activity II
Optimal imaging conditions
Tools for functional connectivity analysis 1
Light sheet microscope for fast 3D imaging of neuron activity I

Demonstrators, pilots, prototypes (1)

Physiological chamber

Pubblicazioni

Peer reviewed articles (8)

The Photobiomodulation of Vital Parameters of the Cancer Cell Culture by Low Dose of Near-IR Laser Irradiation

Autori: Anna Khokhlova, Igor Zolotovskii, Dmitrii Stoliarov, Svetlana Vorsina, Daria Liamina, Evgenia Pogodina, Andrei A. Fotiadi, Sergei G. Sokolovski, Yury Saenko, Edik U. Rafailov
Pubblicato in: IEEE Journal of Selected Topics in Quantum Electronics, Numero 25/1, 2019, Pagina/e 1-10, ISSN 1077-260X
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/jstqe.2018.2854539

Impact of modular organization on dynamical richness in cortical networks

Autori: Hideaki Yamamoto, Satoshi Moriya, Katsuya Ide, Takeshi Hayakawa, Hisanao Akima, Shigeo Sato, Shigeru Kubota, Takashi Tanii, Michio Niwano, Sara Teller, Jordi Soriano, Ayumi Hirano-Iwata
Pubblicato in: Science Advances, Numero 4/11, 2018, Pagina/e eaau4914, ISSN 2375-2548
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aau4914

CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons

Autori: Carles Calatayud, Giulia Carola, Irene Fernández-Carasa, Marco Valtorta, Senda Jiménez-Delgado, Mònica Díaz, Jordi Soriano-Fradera, Graziella Cappelletti, Javier García-Sancho, Ángel Raya, Antonella Consiglio
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-43080-2

Photodynamic opening of blood-brain barrier

Autori: Oxana Semyachkina-Glushkovskaya, Jürgen Kurths, Ekaterina Borisova, Sergei Sokolovski, Vanya Mantareva, Ivan Angelov, Alexander Shirokov, Nikita Navolokin, Natalia Shushunova, Alexander Khorovodov, Maria Ulanova, Madina Sagatova, Ilana Agranivich, Olga Sindeeva, Artem Gekalyuk, Anastasiya Bodrova, and Edik Rafailov
Pubblicato in: Biomedical Optics Express, 2017, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.8.005040

Neuronal spatial arrangement shapes effective connectivity traits of in vitro cortical networks

Autori: Elisenda Tibau Martorell, Adriaan Alexander Ludl, Sten Rudiger, Javier G. Orlandi, Jordi Soriano
Pubblicato in: IEEE Transactions on Network Science and Engineering, 2017, Pagina/e 1-1, ISSN 2327-4697
Editore: IEEE Computer Society
DOI: 10.1109/tnse.2018.2862919

7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington’s disease mouse model through specific activation of the PLCγ1 pathway

Autori: Gerardo García-Díaz Barriga, Albert Giralt, Marta Anglada-Huguet, Nuria Gaja-Capdevila, Javier G. Orlandi, Jordi Soriano, Josep-Maria Canals, Jordi Alberch
Pubblicato in: Human Molecular Genetics, Numero Vol26, No 16, 2017, Pagina/e 3144–3160, ISSN 0964-6906
Editore: Oxford University Press
DOI: 10.1093/hmg/ddx198

STED imaging performance estimation by means of Fourier transform analysis

Autori: David Merino, Arrate Mallabiabarrena, Jordi Andilla, David Artigas, Timo Zimmermann, Pablo Loza-Alvarez
Pubblicato in: Biomedical Optics Express, Numero 8/5, 2017, Pagina/e 2472, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/BOE.8.002472

Sub-diffraction discrimination with polarization-resolved two-photon excited fluorescence microscopy

Autori: David Artigas, David Merino, Christoph Polzer, Pablo Loza-Alvarez
Pubblicato in: Optica, Numero 4/8, 2017, Pagina/e 911, ISSN 2334-2536
Editore: OSA Publishing
DOI: 10.1364/optica.4.000911