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Targeting iNKT cell and adipocyte crosstalk for control of metabolism and body weight

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iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy

Author(s): Lydia Lynch, Andrew E. Hogan, Danielle Duquette, Chantel Lester, Alexander Banks, Katherine LeClair, David E. Cohen, Abhisek Ghosh, Bing Lu, Michelle Corrigan, Darko Stevanovic, Eleftheria Maratos-Flier, Daniel J. Drucker, Donal O’Shea, Michael Brenner
Published in: Cell Metabolism, Issue 24/3, 2016, Page(s) 510-519, ISSN 1550-4131
DOI: 10.1016/j.cmet.2016.08.003

Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity

Author(s): Selma Boulenouar, Xavier Michelet, Danielle Duquette, David Alvarez, Andrew E. Hogan, Christina Dold, Donal O’Connor, Suzanne Stutte, Ali Tavakkoli, Desmond Winters, Mark A. Exley, Donal O’Shea, Michael B. Brenner, Ulrich von Andrian, Lydia Lynch
Published in: Immunity, Issue 46/2, 2017, Page(s) 273-286, ISSN 1074-7613
DOI: 10.1016/j.immuni.2017.01.008

γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis

Author(s): Ayano C. Kohlgruber, Shani T. Gal-Oz, Nelson M. LaMarche, Moto Shimazaki, Danielle Duquette, Hung N. Nguyen, Amir I. Mina, Tyler Paras, Ali Tavakkoli, Ulrich von Andrian, Alexander S. Banks, Tal Shay, Michael B. Brenner, Lydia Lynch
Published in: Nature Immunology, Issue 19/5, 2018, Page(s) 464-474, ISSN 1529-2908
DOI: 10.1038/s41590-018-0094-2

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

Author(s): Xavier Michelet, Lydia Dyck, Andrew Hogan, Roisin M. Loftus, Danielle Duquette, Kevin Wei, Semir Beyaz, Ali Tavakkoli, Cathriona Foley, Raymond Donnelly, Cliona O’Farrelly, Mathilde Raverdeau, Ashley Vernon, William Pettee, Donal O’Shea, Barbara S. Nikolajczyk, Kingston H. G. Mills, Michael B. Brenner, David Finlay, Lydia Lynch
Published in: Nature Immunology, Issue 19/12, 2018, Page(s) 1330-1340, ISSN 1529-2908
DOI: 10.1038/s41590-018-0251-7

Innate Immune Control of Adipose Tissue Homeostasis

Author(s): Harry Kane, Lydia Lynch
Published in: Trends in Immunology, Issue 40/9, 2019, Page(s) 857-872, ISSN 1471-4906
DOI: 10.1016/

Adipose Dendritic Cells Come Out of Hiding

Author(s): Nelson M. LaMarche, Lydia Lynch
Published in: Cell Metabolism, Issue 27/3, 2018, Page(s) 485-486, ISSN 1550-4131
DOI: 10.1016/j.cmet.2018.02.014

New Job for NK Cells: Architects of the Tumor Microenvironment

Author(s): Lydia Dyck, Lydia Lynch
Published in: Immunity, Issue 48/1, 2018, Page(s) 9-11, ISSN 1074-7613
DOI: 10.1016/j.immuni.2018.01.001