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MultIscale precision therapies for NeuroDEvelopmental Disorders

Objective

Neurodevelopmental disorders (NDD) represent an enormous burden for patients, their families, and society. Within EU, the incidence of autism spectrum disorders (ASD) is increasing to over 100 per 10,000 individuals. By comparison, new cases of brain cancers in EU are estimated to be 10 per 10,000. Also, the requirement for lifelong care has a dramatic impact on healthcare costs, with an average lifelong cost per ASD patient of ~ 3.0 MEuro.
The societal and economic impact, the growing incidence, and the lack of any cure call for radical changes in the way NDD are approached. At this aim, MINDED will integrate across three major technologies: nanomedicine, for the precise delivery of therapeutic and imaging agents; molecular neuroscience, for the identification of RNAs modulating key gene expression; cognitive neuroscience robotics, for the development of novel sensorimotor interventional approaches.
The integration of these technologies requires the establishment of a new class of scientists and entrepreneurs trained to stretch their knowledge over multiple disciplines and think outside conventional silos. MINDED bridges together different vertical silos building common foundations for future interdisciplinary careers.
The objective of MINDED is two-fold: develop a highly interdisciplinary post-doctoral training program by integrating nanomedicine, neuroscience and robotics; involve fellows in activities aimed at developing multiscale technologies for NDD. This will be achieved via two training paths: a scientist path, engaging fellows in the development of novel diagnosis and treatment approaches for NDD; a business developer path, engaging fellows on the integration of biomedical technologies in the clinic.
MINDED fellows will constitute a new class of scientists and entrepreneurs capable of developing novel treatment and diagnosis approaches for complex genetic diseases and shaping the future integration of nanomedicine and robotics with neurosciences.

Coordinator

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Net EU contribution
€ 3 398 400,00
Address
Via Morego 30
16163 Genova
Italy

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Region
Nord-Ovest Liguria Genova
Activity type
Research Organisations
Non-EU contribution
€ 3 398 400,00

Partners (15)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

UNIVERSITE PARIS-SACLAY
France
Net EU contribution
€ 0,00
Address
Batiment Breguet - 3 Rue Joliot Curie
91190 Gif-sur-yvette

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Region
Ile-de-France Ile-de-France Essonne
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

DURHAM COUNTY COUNCIL
United Kingdom
Net EU contribution
€ 0,00
Address
County Hall
DH1 5UJ Durham

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Region
North East (England) Tees Valley and Durham Durham CC
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

TEL AVIV UNIVERSITY
Israel
Net EU contribution
€ 0,00
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

UNIVERSIDADE DO MINHO
Portugal
Net EU contribution
€ 0,00
Address
Largo Do Paco
4704 553 Braga

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Region
Continente Norte Cávado
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
Net EU contribution
€ 0,00
Address
Im Neuenheimer Feld 280
69120 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

LULEA TEKNISKA UNIVERSITET
Sweden
Net EU contribution
€ 0,00
Address
Universitetsomradet Porson
971 87 Lulea

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Region
Norra Sverige Övre Norrland Norrbottens län
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
Net EU contribution
€ 0,00
Address
Hofgartenstrasse 8
80539 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

Radboudumc
Netherlands
Net EU contribution
€ 0,00
Address
Geert Grooteplein 21
6500HB Nijmegen

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Region
Oost-Nederland Gelderland Arnhem/Nijmegen
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE
Italy
Net EU contribution
€ 0,00
Address
Via Bonomea 265
34136 Trieste

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Region
Nord-Est Friuli-Venezia Giulia Trieste
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Switzerland
Net EU contribution
€ 0,00
Address
Batiment Ce 3316 Station 1
1015 Lausanne

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Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italy
Net EU contribution
€ 0,00
Address
Via Zamboni 33
40126 Bologna

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Region
Nord-Est Emilia-Romagna Bologna
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
United States
Net EU contribution
€ 0,00
Address
Serra Mall 450
94305 2004 Stanford

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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

FORSCHUNGSZENTRUM JULICH GMBH
Germany
Net EU contribution
€ 0,00
Address
Wilhelm Johnen Strasse
52428 Julich

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Region
Nordrhein-Westfalen Köln Düren
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

CHARLES RIVER DISCOVERY RESEARCH SERVICES FINLAND OY
Finland
Net EU contribution
€ 0,00
Address
Microkatu 1
70210 Kuopio

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Savo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

UNIVERSITY COLLEGE LONDON
United Kingdom
Net EU contribution
€ 0,00
Address
Gower Street
WC1E 6BT London

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00