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Exploiting GLIOblastoma intractability to address European research TRAINing needs in translational brain tumour research, cancer systems medicine and integrative multi-omics

Deliverables

Dissemination and public engagement Report 1

Dissemination and public engagement reports

Dissemination and public engagement Report 2

Dissemination and public engagement reports

GLIOTRAIN Web presence

Website, Twitter, Facebook Page construction

Publications

Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism

Author(s): Frank A. Lincoln, Dirke Imig, Chiara Boccellato, Viktorija Juric, Janis Noonan, Roland E. Kontermann, Frank Allgöwer, Brona M. Murphy, Markus Rehm
Published in: Cell Death & Disease, Issue 9/11, 2018, Page(s) 1112, ISSN 2041-4889
DOI: 10.1038/s41419-018-1160-2

Bax retrotranslocation potentiates Bcl-xL’s antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance

Author(s): Annika Hantusch; Kushal K. Das; Ana J. García-Sáez; Thomas Brunner; Markus Rehm
Published in: Cell Death & Disease, Issue 9 (4), 2018, Page(s) 430, ISSN 2041-4889
DOI: 10.1038/s41419-018-0464-6

RGD-decorated cholesterol stabilized polyplexes for targeted siRNA delivery to glioblastoma cells

Author(s): Bo Lou, Kate Connor, Kieron Sweeney, Ian S. Miller, Alice O’Farrell, Eduardo Ruiz-Hernandez, David M. Murray, Garry P. Duffy, Alan Wolfe, Enrico Mastrobattista, Annette T. Byrne, Wim E. Hennink
Published in: Drug Delivery and Translational Research, Issue 9/3, 2019, Page(s) 679-693, ISSN 2190-393X
DOI: 10.1007/s13346-019-00637-y

Durability of cell line xenograft resection models to interrogate tumor micro-environment targeting agents

Author(s): Ian S. Miller, Liam P. Shiels, Emer Conroy, Kate Connor, Patrick Dicker, William M. Gallagher, Norma O’ Donovan, Robert S. Kerbel, John Crown, Annette T. Byrne
Published in: Scientific Reports, Issue 9/1, 2019, Page(s) 9204, ISSN 2045-2322
DOI: 10.1038/s41598-019-45444-0

Datasets

Generation, characterization and drug sensitivities of twelve patient-derived IDH1 mutant glioma cell cultures

Author(s): Verheul, Cassandra; Ntafoulis, Ioannis; Kers, Trisha V.; Hoogstrate, Youri; Mastroberardino, Pier G.; Barnhoorn, Sander; Payán-Gómez, César; Tching Chi Yen, Romain; Struys, Eduard A.; Koolen, Stijn L.W.; Dirven, Clemens M.F.; Leenstra, Sieger; French, Pim J.; Lamfers, Martine L.M.
Published in: Zenodo

Generation, characterization and drug sensitivities of twelve patient-derived IDH1 mutant glioma cell cultures

Author(s): Verheul, Cassandra; Ntafoulis, Ioannis; Kers, Trisha V.; Hoogstrate, Youri; Mastroberardino, Pier G.; Barnhoorn, Sander; Payán-Gómez, César; Tching Chi Yen, Romain; Struys, Eduard A.; Koolen, Stijn L.W.; Dirven, Clemens M.F.; Leenstra, Sieger; French, Pim J.; Lamfers, Martine L.M.
Published in: Zenodo

Software

System-based Approaches as Prognostic Tools for Glioblastoma: Version 1.1

Author(s): Salvucci*, Manuela; Zaitun Zakaria*; Carberry, Steven; Tivnan, Amanda; Seifert, Volker; Kögel, Donat; Brona M. Murphy; Prehn, Jochen H.M.
DOI: 10.5281/zenodo.1204125; 10.5281/zenodo.1204124; 10.5281/zenodo.3473419
Publisher: Zenodo