Deliverables Documents, reports (5) Dissemination and public engagement Report 4 Dissemination and public engagement reports Dissemination and public engagement Report 1 Dissemination and public engagement reports Dissemination and public engagement Report 2 Dissemination and public engagement reports Dissemination and public engagement Report 3 Dissemination and public engagement reports Report on GLIOTRAIN conference Report on GLIOTRAIN conference Websites, patent fillings, videos etc. (1) GLIOTRAIN Web presence Website, Twitter, Facebook Page construction Publications Peer reviewed articles (21) Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM Author(s): Viktorija Juric, Heiko Düssmann, Martine L. M. Lamfers, Jochen H. M. Prehn, Markus Rehm, Brona M. Murphy Published in: Cells, Issue 10/5, 2021, Page(s) 1182, ISSN 2073-4409 Publisher: MDPI DOI: 10.3390/cells10051182 The influence of methylation status on a stochastic model of MGMT dynamics in glioblastoma: Phenotypic selection can occur with and without a downshift in promoter methylation status Author(s): Ayoub Lasri, Marc Sturrock Published in: Journal of Theoretical Biology, Issue 521, 2021, Page(s) 110662, ISSN 0022-5193 Publisher: Academic Press DOI: 10.1016/j.jtbi.2021.110662 Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology Author(s): Anna Golebiewska, Ann-Christin Hau, Anaïs Oudin, Daniel Stieber, Yahaya A. Yabo, Virginie Baus, Vanessa Barthelemy, Eliane Klein, Sébastien Bougnaud, Olivier Keunen, May Wantz, Alessandro Michelucci, Virginie Neirinckx, Arnaud Muller, Tony Kaoma, Petr V. Nazarov, Francisco Azuaje, Alfonso De Falco, Ben Flies, Lorraine Richart, Suresh Poovathingal, Thais Arns, Kamil Grzyb, Andreas Mock, Christel Published in: Acta Neuropathologica, Issue 140/6, 2020, Page(s) 919-949, ISSN 0001-6322 Publisher: Springer Verlag DOI: 10.1007/s00401-020-02226-7 Cyclin-dependent kinase inhibitors in brain cancer: current state and future directions Author(s): Viktorija Juric, Brona Murphy Published in: Cancer Drug Resistance, Issue 3, 2020, Page(s) 48-62, ISSN 2578-532X Publisher: OAE Publishing Inc DOI: 10.20517/cdr.2019.105 Linking hyperosmotic stress and apoptotic sensitivity. Author(s): Daniela Stöhr; Markus Rehm Published in: The FEBS Journal, Issue 288/6, 2021, Page(s) 1800-1803, ISSN 1742-464X Publisher: Blackwell Publishing Inc. DOI: 10.1111/febs.15520 Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation Author(s): Viktorija Juric, Lance Hudson, Joanna Fay, Cathy E. Richards, Hanne Jahns, Maïté Verreault, Franck Bielle, Ahmed Idbaih, Martine L. M. Lamfers, Ann M. Hopkins, Markus Rehm, Brona M. Murphy Published in: Cell Death & Disease, Issue 12/8, 2021, Page(s) 763, ISSN 2041-4889 Publisher: Nature Publishing Group DOI: 10.1038/s41419-021-04050-7 Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors Author(s): Anaïs Oudin, Virginie Baus, Vanessa Barthelemy, Carina Fabian, Eliane Klein, Monika Dieterle, May Wantz, Ann-Christin Hau, Claire Dording, Amandine Bernard, Alessandro Michelucci, Yahaya A. Yabo, Georgia Kanli, Olivier Keunen, Rolf Bjerkvig, Simone P. Niclou, Anna Golebiewska Published in: STAR Protocols, Issue 2/2, 2021, Page(s) 100534, ISSN 2666-1667 Publisher: Cell Press DOI: 10.1016/j.xpro.2021.100534 Master regulators associated with poor prognosis in glioblastoma multiforme Author(s): M P Kalya, T Beisbarth, A Kel Published in: Biomeditsinskaya khimiya, Issue 67/3, 2021, Page(s) 201-212, ISSN 2310-6972 Publisher: Institute of Biomedical Chemistry DOI: 10.18097/pbmc20216703201 New hints towards a precision medicine strategy for IDH wild-type glioblastoma Author(s): K. White, K. Connor, J. Clerkin, B.M. Murphy, M. Salvucci, A.C. O'Farrell, M. Rehm, D. O'Brien, J.H.M. Prehn, S.P. Niclou, M.L.M. Lamfers, M. Verreault, A. Idbaih, R. Verhaak, A. Golebiewska, A.T. Byrne Published in: Annals of Oncology, Issue 31/12, 2020, Page(s) 1679-1692, ISSN 0923-7534 Publisher: Oxford University Press DOI: 10.1016/j.annonc.2020.08.2336 Phenotypic selection through cell death: stochastic modelling of O-6-methylguanine-DNA methyltransferase dynamics Author(s): Ayoub Lasri, Viktorija Juric, Maité Verreault, Franck Bielle, Ahmed Idbaih, Alexander Kel, Brona Murphy, Marc Sturrock Published in: Royal Society Open Science, Issue 7/7, 2020, Page(s) 191243, ISSN 2054-5703 Publisher: Royal Society Publishing DOI: 10.1098/rsos.191243 IGFBP2 Is a Potential Master Regulator Driving the Dysregulated Gene Network Responsible for Short Survival in Glioblastoma Multiforme Author(s): Manasa Kalya, Alexander Kel, Darius Wlochowitz, Edgar Wingender, Tim Beißbarth Published in: Frontiers in Genetics, Issue 12, 2021, ISSN 1664-8021 Publisher: Frontiers Media DOI: 10.3389/fgene.2021.670240 Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism Author(s): Frank A. Lincoln, Dirke Imig, Chiara Boccellato, Viktorija Juric, Janis Noonan, Roland E. Kontermann, Frank Allgöwer, Brona M. Murphy, Markus Rehm Published in: Cell Death & Disease, Issue 9/11, 2018, Page(s) 1112, ISSN 2041-4889 Publisher: Nature Publishing Group DOI: 10.1038/s41419-018-1160-2 Bax retrotranslocation potentiates Bcl-xL’s antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance Author(s): Annika Hantusch; Kushal K. Das; Ana J. García-Sáez; Thomas Brunner; Markus Rehm Published in: Cell Death & Disease, Issue 9 (4), 2018, Page(s) 430, ISSN 2041-4889 Publisher: Nature Publishing Group DOI: 10.1038/s41419-018-0464-6 RGD-decorated cholesterol stabilized polyplexes for targeted siRNA delivery to glioblastoma cells Author(s): Bo Lou, Kate Connor, Kieron Sweeney, Ian S. Miller, Alice O’Farrell, Eduardo Ruiz-Hernandez, David M. Murray, Garry P. Duffy, Alan Wolfe, Enrico Mastrobattista, Annette T. Byrne, Wim E. Hennink Published in: Drug Delivery and Translational Research, Issue 9/3, 2019, Page(s) 679-693, ISSN 2190-393X Publisher: Springer Pub. Co., DOI: 10.1007/s13346-019-00637-y Durability of cell line xenograft resection models to interrogate tumor micro-environment targeting agents Author(s): Ian S. Miller, Liam P. Shiels, Emer Conroy, Kate Connor, Patrick Dicker, William M. Gallagher, Norma O’ Donovan, Robert S. Kerbel, John Crown, Annette T. Byrne Published in: Scientific Reports, Issue 9/1, 2019, Page(s) 9204, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-019-45444-0 Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies Author(s): Kate Connor, David W. Murray, Monika A. Jarzabek, Nhan L. Tran, Kieron White, Patrick Dicker, Kieron J. Sweeney, Philip J. O’Halloran, Brian MacCarthy, Liam P. Shiels, Francesca Lodi, Diether Lambrechts, Jann N. Sarkaria, Raymond M. Schiffelers, Marc Symons, Annette T. Byrne Published in: Cancers, Issue 12/12, 2020, Page(s) 3531, ISSN 2072-6694 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers12123531 Implementing Patient-Derived Xenografts to Assess the Effectiveness of Cyclin-Dependent Kinase Inhibitors in Glioblastoma Author(s): Janis J. Noonan, Monika Jarzabek, Frank A. Lincoln, Brenton L. Cavanagh, Arhona R. Pariag, Viktorija Juric, Leonie S. Young, Keith L. Ligon, Hanne Jahns, Daniella Zheleva, Jochen H. M. Prehn, Markus Rehm, Annette T. Byrne, Brona M. Murphy Published in: Cancers, Issue 11/12, 2019, Page(s) 2005, ISSN 2072-6694 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers11122005 Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist Author(s): Chiara Boccellato, Emily Kolbe, Nathalie Peters, Viktorija Juric, Gavin Fullstone, Maïté Verreault, Ahmed Idbaih, Martine L. M. Lamfers, Brona M. Murphy, Markus Rehm Published in: Cell Death & Disease, Issue 12/7, 2021, ISSN 2041-4889 Publisher: Nature Publishing Group DOI: 10.1038/s41419-021-03927-x Generation, characterization, and drug sensitivities of 12 patient-derived IDH1-mutant glioma cell cultures Author(s): Cassandra Verheul, Ioannis Ntafoulis, Trisha V Kers, Youri Hoogstrate, Pier G Mastroberardino, Sander Barnhoorn, César Payán-Gómez, Romain Tching Chi Yen, Eduard A Struys, Stijn L W Koolen, Clemens M F Dirven, Sieger Leenstra, Pim J French, Martine L M Lamfers Published in: Neuro-Oncology Advances, Issue 3/1, 2021, ISSN 2632-2498 Publisher: Oxford Academic DOI: 10.1093/noajnl/vdab103 System-based approaches as prognostic tools for glioblastoma Author(s): Manuela Salvucci, Zaitun Zakaria, Steven Carberry, Amanda Tivnan, Volker Seifert, Donat Kögel, Brona M. Murphy, Jochen H. M. Prehn Published in: BMC Cancer, Issue 19/1, 2019, Page(s) 1092, ISSN 1471-2407 Publisher: BioMed Central DOI: 10.1186/s12885-019-6280-2 Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization Author(s): Ana Rita Pombo Antunes, Isabelle Scheyltjens, Francesca Lodi, Julie Messiaen, Asier Antoranz, Johnny Duerinck, Daliya Kancheva, Liesbet Martens, Karen De Vlaminck, Hannah Van Hove, Signe Schmidt Kjølner Hansen, Francesca Maria Bosisio, Koen Van der Borght, Steven De Vleeschouwer, Raf Sciot, Luc Bouwens, Michiel Verfaillie, Niels Vandamme, Roosmarijn E. Vandenbroucke, Olivier De Wever, Yvan Saeys, Published in: Nature Neuroscience, Issue 24/4, 2021, Page(s) 595-610, ISSN 1097-6256 Publisher: Nature Publishing Group DOI: 10.1038/s41593-020-00789-y Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
