Understanding the evolution of plasmid-mediated antibiotic resistance in real life scenarios

Publications

Peer reviewed articles (7)

Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients

Author(s): Ricardo León-Sampedro, Javier DelaFuente, Cristina Díaz-Agero, Thomas Crellen, Patrick Musicha, Jerónimo Rodríguez-Beltrán, Carmen de la Vega, Marta Hernández-García, R-GNOSIS WP5 Study Group , Nieves López-Fresneña, Patricia Ruiz-Garbajosa, Rafael Cantón, Ben S Cooper, Álvaro San Millán
Published in: Nature Microbiology, 2021, ISSN 2058-5276
Publisher: Nature Publishing Group
DOI: 10.1038/s41564-021-00879-y

Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities

Author(s): Alonso-Del Valle A, León-Sampedro R, Rodríguez-Beltrán J, DelaFuente J, Hernández-García M, Ruiz-Garbajosa P, Cantón R, Peña-Miller R, San Millán A.
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22849-y

Collateral sensitivity associated with antibiotic resistance plasmids.

Author(s): Herencias C, Rodríguez-Beltrán J, León-Sampedro R, Alonso-Del Valle A, Palkovičová J, Cantón R, San Millán Á.
Published in: eLife, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.65130

Evolution of Plasmid-Mediated Antibiotic Resistance in the Clinical Context

Author(s): Alvaro San Millan
Published in: Trends in Microbiology, monthly, 2018, ISSN 0966-842X
Publisher: Elsevier BV
DOI: 10.1016/j.tim.2018.06.007

The evolution of antibiotic resistance

Author(s): R. Craig MacLean, Alvaro San Millan
Published in: Science, 365/6458, 2019, Page(s) 1082-1083, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aax3879

Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria

Author(s): Jerónimo Rodríguez-Beltrán, Vidar Sørum, Macarena Toll-Riera, Carmen de la Vega, Rafael Peña-Miller, Álvaro San Millán
Published in: Proceedings of the National Academy of Sciences, 117/27, 2020, Page(s) 15755-15762, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2001240117

Translational demand is not a major source of plasmid-associated fitness costs

Author(s): Rodríguez-Beltrán J, León-Sampedro R, Ramiro-Martínez P, de la Vega C, Baquero F, Levin BR, San Millán Á.
Published in: Philos Trans R Soc Lond B Biol Sci, 2021, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2020.0463

Other (2)

Dissemination routes of the carbapenem resistance plasmid pOXA-48 in a hospital setting

Author(s): León-Sampedro, Ricardo; DelaFuente, Javier; Díaz-Agero, Cristina; Crellen, Thomas; Musicha, Patrick; Rodriguez-Beltran, Jerónimo; de la Vega, Carmen; Hernández-García, Marta; Lopez-Fresneña, Nieves; Ruiz-Garbajosa, Patricia; Canton, Rafael; Cooper, Ben S; Millan, Alvaro San
Published in: bioRxiv, 2020
Publisher: Cold Spring Harbor Laboratpry
DOI: 10.1101/2020.04.20.050476

The distribution of plasmid fitness effects explains plasmid persistence in bacterial communities

Author(s): Aida Alonso-del Valle, León-Sampedro, Jerónimo Rodríguez-Beltrán, Javier DelaFuente, Marta Hernández-García,Patricia Ruiz-Garbajosa, Rafael Cantón, Rafael Peña-Miller, Álvaro San Millán
Published in: bioRxiv, 2020
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.08.01.230672

Book chapters (1)

Methods to Study Fitness and Compensatory Adaptation in Plasmid-Carrying Bacteria

Author(s): Javier DelaFuente, Jeronimo Rodriguez-Beltran, Alvaro San Millan
Published in: Horizontal Gene Transfer - Methods and Protocols, 2075, 2020, Page(s) 371-382, ISBN 978-1-4939-9876-0
Publisher: Springer US
DOI: 10.1007/978-1-4939-9877-7_26