Understanding the evolution of plasmid-mediated antibiotic resistance in real life scenarios

Publicaciones

The distribution of fitness effects of plasmid pOXA-48 in clinical enterobacteria

Autores: Ariadna Fernández-Calvet, Laura Toribio-Celestino, Aida Alonso-Del Valle, Jorge Sastre-Dominguez, Paula Valdes-Chiara, Alvaro San Millan, Javier DelaFuente
Publicado en: Microbiology, 2023, ISSN 0026-2617
Editor: Maik Nauka/Interperiodica Publishing
DOI: 10.1099/mic.0.001369

Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients

Autores: Ricardo León-Sampedro, Javier DelaFuente, Cristina Díaz-Agero, Thomas Crellen, Patrick Musicha, Jerónimo Rodríguez-Beltrán, Carmen de la Vega, Marta Hernández-García, R-GNOSIS WP5 Study Group , Nieves López-Fresneña, Patricia Ruiz-Garbajosa, Rafael Cantón, Ben S Cooper, Álvaro San Millán
Publicado en: Nature Microbiology, 2021, ISSN 2058-5276
Editor: Nature Publishing Group
DOI: 10.1038/s41564-021-00879-y

Within-patient evolution of plasmid-mediated antimicrobial resistance

Autores: DelaFuente J, Toribio-Celestino L, Santos-Lopez A, León-Sampedro R, Alonso-Del Valle A, Costas C, Hernández-García M, Cui L, Rodríguez-Beltrán J, Bikard D, Cantón R, San Millan A
Publicado en: Nature Ecology and Evolution, Edición 6, 2022, Página(s) 1980–1991, ISSN 2397-334X
Editor: Nature Publishing Group
DOI: 10.1038/s41559-022-01908-7

Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities

Autores: Alonso-Del Valle A, León-Sampedro R, Rodríguez-Beltrán J, DelaFuente J, Hernández-García M, Ruiz-Garbajosa P, Cantón R, Peña-Miller R, San Millán A.
Publicado en: Nature Communications, 2021, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-22849-y

Collateral sensitivity associated with antibiotic resistance plasmids.

Autores: Herencias C, Rodríguez-Beltrán J, León-Sampedro R, Alonso-Del Valle A, Palkovičová J, Cantón R, San Millán Á.
Publicado en: eLife, 2021, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.65130

Antimicrobial resistance level and conjugation permissiveness shape plasmid distribution in clinical enterobacteria

Autores: Aida Alonso-Del Valle, Laura Toribio-Celestino, Anna Quirant, Carles Tardio Pi, Javier DelaFuente, Rafael Canton, Eduardo P C Rocha, Carles Ubeda, Rafael Peña-Miller, Alvaro San Millan
Publicado en: Proceedings of the National Academy of Sciences of the USA, 2023, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2314135120

Evolution of Plasmid-Mediated Antibiotic Resistance in the Clinical Context

Autores: Alvaro San Millan
Publicado en: Trends in Microbiology, Edición monthly, 2018, ISSN 0966-842X
Editor: Elsevier BV
DOI: 10.1016/j.tim.2018.06.007

The evolution of antibiotic resistance

Autores: R. Craig MacLean, Alvaro San Millan
Publicado en: Science, Edición 365/6458, 2019, Página(s) 1082-1083, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.aax3879

Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria

Autores: Jerónimo Rodríguez-Beltrán, Vidar Sørum, Macarena Toll-Riera, Carmen de la Vega, Rafael Peña-Miller, Álvaro San Millán
Publicado en: Proceedings of the National Academy of Sciences, Edición 117/27, 2020, Página(s) 15755-15762, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2001240117

Translational demand is not a major source of plasmid-associated fitness costs

Autores: Rodríguez-Beltrán J, León-Sampedro R, Ramiro-Martínez P, de la Vega C, Baquero F, Levin BR, San Millán Á.
Publicado en: Philos Trans R Soc Lond B Biol Sci, 2021, ISSN 0962-8436
Editor: Royal Society of London
DOI: 10.1098/rstb.2020.0463

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