Understanding the evolution of plasmid-mediated antibiotic resistance in real life scenarios

Pubblicazioni

The distribution of fitness effects of plasmid pOXA-48 in clinical enterobacteria

Autori: Ariadna Fernández-Calvet, Laura Toribio-Celestino, Aida Alonso-Del Valle, Jorge Sastre-Dominguez, Paula Valdes-Chiara, Alvaro San Millan, Javier DelaFuente
Pubblicato in: Microbiology, 2023, ISSN 0026-2617
Editore: Maik Nauka/Interperiodica Publishing
DOI: 10.1099/mic.0.001369

Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients

Autori: Ricardo León-Sampedro, Javier DelaFuente, Cristina Díaz-Agero, Thomas Crellen, Patrick Musicha, Jerónimo Rodríguez-Beltrán, Carmen de la Vega, Marta Hernández-García, R-GNOSIS WP5 Study Group , Nieves López-Fresneña, Patricia Ruiz-Garbajosa, Rafael Cantón, Ben S Cooper, Álvaro San Millán
Pubblicato in: Nature Microbiology, 2021, ISSN 2058-5276
Editore: Nature Publishing Group
DOI: 10.1038/s41564-021-00879-y

Within-patient evolution of plasmid-mediated antimicrobial resistance

Autori: DelaFuente J, Toribio-Celestino L, Santos-Lopez A, León-Sampedro R, Alonso-Del Valle A, Costas C, Hernández-García M, Cui L, Rodríguez-Beltrán J, Bikard D, Cantón R, San Millan A
Pubblicato in: Nature Ecology and Evolution, Numero 6, 2022, Pagina/e 1980–1991, ISSN 2397-334X
Editore: Nature Publishing Group
DOI: 10.1038/s41559-022-01908-7

Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities

Autori: Alonso-Del Valle A, León-Sampedro R, Rodríguez-Beltrán J, DelaFuente J, Hernández-García M, Ruiz-Garbajosa P, Cantón R, Peña-Miller R, San Millán A.
Pubblicato in: Nature Communications, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-22849-y

Collateral sensitivity associated with antibiotic resistance plasmids.

Autori: Herencias C, Rodríguez-Beltrán J, León-Sampedro R, Alonso-Del Valle A, Palkovičová J, Cantón R, San Millán Á.
Pubblicato in: eLife, 2021, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.65130

Antimicrobial resistance level and conjugation permissiveness shape plasmid distribution in clinical enterobacteria

Autori: Aida Alonso-Del Valle, Laura Toribio-Celestino, Anna Quirant, Carles Tardio Pi, Javier DelaFuente, Rafael Canton, Eduardo P C Rocha, Carles Ubeda, Rafael Peña-Miller, Alvaro San Millan
Pubblicato in: Proceedings of the National Academy of Sciences of the USA, 2023, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2314135120

Evolution of Plasmid-Mediated Antibiotic Resistance in the Clinical Context

Autori: Alvaro San Millan
Pubblicato in: Trends in Microbiology, Numero monthly, 2018, ISSN 0966-842X
Editore: Elsevier BV
DOI: 10.1016/j.tim.2018.06.007

The evolution of antibiotic resistance

Autori: R. Craig MacLean, Alvaro San Millan
Pubblicato in: Science, Numero 365/6458, 2019, Pagina/e 1082-1083, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aax3879

Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria

Autori: Jerónimo Rodríguez-Beltrán, Vidar Sørum, Macarena Toll-Riera, Carmen de la Vega, Rafael Peña-Miller, Álvaro San Millán
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 117/27, 2020, Pagina/e 15755-15762, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2001240117

Translational demand is not a major source of plasmid-associated fitness costs

Autori: Rodríguez-Beltrán J, León-Sampedro R, Ramiro-Martínez P, de la Vega C, Baquero F, Levin BR, San Millán Á.
Pubblicato in: Philos Trans R Soc Lond B Biol Sci, 2021, ISSN 0962-8436
Editore: Royal Society of London
DOI: 10.1098/rstb.2020.0463

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