CORDIS
EU research results

CORDIS

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''One size fits all'' unique drug to eradicate multiple viral species simultaneously from the central nervous system of co-infected individuals

Project information

Grant agreement ID: 828774

Status

Ongoing project

  • Start date

    1 September 2019

  • End date

    31 August 2023

Funded under:

H2020-EU.1.2.1.

  • Overall budget:

    € 3 933 965,63

  • EU contribution

    € 3 933 965,63

Coordinated by:

INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES

Portugal

Project description

English EN

Development of universal drug to target viral co-infection in the nervous system

Zika, dengue, chikungunya, HIV and measles claim thousands of victims each year. These viral infections of the central nervous system cause neurological impairment. Zika, dengue and chikungunya viruses are spread mainly by mosquitoes of the Aedes genus. Zika virus can get through the blood-placental barrier and then the developing blood-brain barrier of the foetus, causing newborn microcephaly and neurological disorders. Current drug development strategies completely overlook the reality of co-infection for these viruses. The EU-funded NOVIRUSES2BRAIN project will identify and select universal drug candidates that translocate blood-placental and blood-brain barriers to target these viruses, even during pregnancy. This project has international scope, including experts in medicinal chemistry, biochemistry, virology and drug development. NOVIRUSES2BRAIN aims to create a drug that clears all viral species from the brain simultaneously.

Coordinator

INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES

Address

Avenida Prof Egas Moniz
1649 028 Lisboa

Portugal

Activity type

Research Organisations

EU Contribution

€ 2 113 125

Participants (2)

UNIVERSIDAD POMPEU FABRA

Spain

EU Contribution

€ 1 272 840,63

SYNOVO GMBH

Germany

EU Contribution

€ 548 000

Project information

Grant agreement ID: 828774

Status

Ongoing project

  • Start date

    1 September 2019

  • End date

    31 August 2023

Funded under:

H2020-EU.1.2.1.

  • Overall budget:

    € 3 933 965,63

  • EU contribution

    € 3 933 965,63

Coordinated by:

INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES

Portugal