Project description
Innovative device to monitor hybrid skin wound healing
Researchers have employed tissue engineering to develop advanced skin substitutes for regeneration and replacement. However, a pressing challenge is the lack of an effective method for real-time monitoring of their healing progress. The MSCA-funded BioKIN project aims to establish an in vitro biomimetic platform for the remote and non-destructive real-time monitoring of laboratory-grown skin. This project will create a device that interfaces with bioengineered skin tissue, resulting in a functional hybrid skin. This hybrid skin will facilitate the study of biological processes and the monitoring of wound healing in a laboratory setting. Importantly, BioKIN will augment bioengineered skin tissue with non-biological capabilities, enabling a deeper understanding of epidermal biology, tissue formation and skin diseases.
Objective
The BioKIN project aims to engineer a biomimetic in vitro platform for the non-destructive, remote, and real-time monitoring of laboratory-grown skin. The project is focused on developing a seamless device to interface with bioengineered skin tissue. Strategies will be established to integrate the device with skin cells to mature hybrid functional skin, where electronics and tissue grow alike. The obtained hybrid functional tissue will provide a powerful tool to study skin biological processes, which will be used early by monitoring wound healing in vitro. Every year, over 50 million patients suffer from severe skin injuries such as burns and chronic wounds and need effective therapies to restore skin function. Fueled by this need, researchers have developed advanced skin substitutes for skin regeneration and replacement by tissue engineering techniques. Despite the incremental improvement of bioengineered skin and its use to regenerate damaged injuries, in situ, non-destructive, and real-time monitoring of their performance has not been sufficiently addressed. BioKIN will equip bioengineered skin tissue with advanced, non-biological capabilities, thus providing a promising platform that supports the understanding of epidermal biology, tissue formation, and skin diseases. The multidisciplinary skills gained during this action BioKIN will significantly enhance the applicant’s future career prospects in bringing bioelectronics to skin tissue engineering.
Fields of science (EuroSciVoc)
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
52428 JULICH
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.