Project description
Advancing carbohydrate research through collaborative innovation
Carbohydrates are essential molecules in nature, playing pivotal roles in many biological processes such as fertilisation, immune responses, and disease progression, including diabetes, infection, and cancer metastasis. The ability to understand, monitor, and intervene in these processes is crucial for advancing medicinal therapies and glycobiology. A major challenge lies in developing carbohydrate-binding molecules (CBMs) capable of selectively binding various carbohydrate structures, from simple sugars to complex glycoconjugates. These CBMs have vast potential in applications like molecular separation, sensing, and selective chemistry. Supported by the Marie Skłodowska-Curie Actions programme, the ENSCC aims to unite Europe’s top expertise in CBM design and application. The project will train PhD students and help advance the field globally.
Objective
Carbohydrates are nature’s most abundant and versatile molecules and are involved in several diseases (e.g. diabetes, infection, and
cancer metastasis) and other regular processes (e.g. fertilization, immune surveillance and inflammatory responses). Understanding,
monitoring and intervening in these processes could be exploited in medicinal therapies, glycobiology, and biomedical research in
general. Such applications are predicated on the availability of carbohydrate binding molecules (CBMs) that can selectively and
supramolecularly (noncovalently) bind a plethora of carbohydrate molecules ranging from simple monosaccharides to complex
oligosaccharides and glycoconjugates. Technologies that can be developed based on CBMs include: the separation and isolation of
carbohydrate containing molecules; making carbohydrate sensing and detection devices; enabling selective chemistry on
(unprotected) carbohydrates; and a range of bio-functional applications.
While the expertise to design, synthesize, study and exploit CBMs is mostly European, the research groups active in this emerging
field work independent from each other. With this doctoral network grant, we aim to unite this expertise in the ‘European Network for
the Supramolecular Chemistry of Carbohydrates’ (ENSCC). With most of the world’s leading minds on the topic and three companies
that are spearheading technologies in the field, our ENSCC will be a European powerhouse that will lead the academic field globally
for years to come. This will be achieved by sharing expertise, key-infrastructure, molecular building blocks, and –most importantly– by
together training the ten PhDs that this doctoral network grant will fund. This training by a unique network of world-leaders, experts
in the field and companies with an interest in CBMs will perfectly position our PhD students to further develop the field by continuing
their career in academia and/or industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine endocrinology diabetes
- natural sciences biological sciences biochemistry biomolecules carbohydrates
- medical and health sciences clinical medicine oncology
You need to log in or register to use this function
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-DN-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
50121 Florence
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.