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Restoring organ microphysiology via intravital ultracompact biopriniting endoscope

Project description

Maximising potential of minimally invasive surgery with 3D tech

Minimally invasive diagnostic and surgical tools have transformed medical procedures globally, offering precision and reduced trauma. However, current techniques are limited to conventional micro-optical imaging and mechanical routines, lacking the ability to recreate intact biological structures. Ideally, medical interventions should restore both structure and function at the target site. With the support of the Marie Skłodowska-Curie Actions programme, the CORE-3D project seeks to integrate advanced 3D manufacturing technologies into endoscopic devices. By combining additive and subtractive manufacturing, CORE-3D aims to develop miniaturised endoscopes capable of visualising and regenerating organ structures intravitally, promising safer and more effective medical interventions.

Objective

Minimally invasive diagnostic and surgical tools have become a staple in modern medical routines worldwide. Endoscopes, a few millimeters in size, are inserted directly into the organ or cavities inside the body, allowing for high precision and fewer trauma-containing procedures. So far, these minimally invasive procedures have been limited to conventional micro-optical imaging and micro-mechanical surgical routines, such as cutting and making small incisions. Ideally, any medical intervention should be capable of re-creating intact biological ultra-structure and function directly at the target site following the most relevant cytocompatible approaches. This proposal seeks to implement noninvasive methods yield to obtain safeguarded, integrated, and improved cutting-edge additive and subtractive 3D manufacturing technologies for developing a miniaturized endoscopic device for organ structure and function intravital regeneration.

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Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

(opens in new window) HORIZON-MSCA-2022-PF-01

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Coordinator

UNIVERSITY OF STUTTGART
Net EU contribution
€ 189 687,36
Address
KEPLERSTRASSE 7
70174 Stuttgart
Germany
Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Higher or Secondary Education Establishments
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Total cost
No data