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Intelligent Breast Cancer DiagnOsis and MonItoring Therapeutic Response Training Network

Project description

A breakthrough in precision diagnostics and treatement for breast cancer

Breast cancer diagnosis and treatment face persistent challenges, with current methods often lacking the precision and ease of use required for optimal patient care. Existing techniques may lead to misdiagnosis, delayed intervention or non-adapted treatment. With the support of the Marie Skłodowska-Curie Actions programme, the CanDoIt project aims to integrate breakthrough technology – a multimodal, multi-physical biosensor array for the identification and quantification of peripheral biomarkers in liquid biopsies. By collaborating with industry and academia, the project will develop breast cancer diagnostic technologies and establish a high-impact structure for extensive dissemination. The overall goal is to revolutionise breast cancer research and treatment, bringing forth a new era of accuracy and efficiency in diagnostics and therapeutic monitoring.

Objective

CanDoIt will show how a smart multimodal multi-physic sensor array associated with DNA oligonucleotides and their peptide nucleic acid (PNAs) analogues dedicated for liquid biopsies analysis has the potential for more accurate diagnostic and treatment monitoring of BC through the study of cutting-edge technologies in bio/nanomaterials, sensors and transducers design, fluidics systems, and artificial intelligence. The CanDoIt objectives are to: (1) Train the excellent next generation researchers for interdisciplinary careers in basic, applied and especially translational BC research and with “raising awareness” on social issues; (2) Develop cutting-edge technologies for BC diagnosis and monitoring therapeutic response by bringing together eminent experts from both industry and academia, including engineers, computational scientists, chemists, physicists, and clinicians; (3) Pursue key biological targets through intelligent methods, all the way from early stage to preclinical and clinical investigation; (4) In addition to respond to the BC issue, the intelligent biosystems proposed will be a real technological advance (breakthrough), thanks to the association of different transducers to go towards a multimodal platform, the association of structured nanomaterials inspired by living world and an implementation of intelligent algorithms for optimal analysis; (5) Build a high-impact structure ensuring multi-level dissemination and exploitation of all results.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks

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Call for proposal

(opens in new window) HORIZON-MSCA-2022-DN-01

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Coordinator

CENTRALE LILLE INSTITUT
Net EU contribution
€ 282 693,60
Address
CITE SCIENTIFIQUE, BOULEVARD PAUL LANGEVIN
59651 Villeneuve D Ascq Cedex
France
Region
Hauts-de-France Nord-Pas de Calais Nord
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data

Participants (6)

Partners (10)