Project description
A non-invasive solution for detecting heart failure
Chronic heart failure is a progressive condition marked by recurring episodes of decompensation, when the heart is unable to maintain adequate circulation to meet the body’s needs. These episodes require hospitalisation but are difficult to predict as they often appear late. Haemodynamic monitoring can detect heart function changes, but it involves invasive devices. With the support of the Marie Skłodowska-Curie Actions programme, the SoundTrack-HF project proposes to develop a non-invasive, home-based system that uses self-recorded heart sounds. Researchers will employ AI to correlate time-related biomarkers with echocardiographic data and predict decompensation episodes in advance, improving outcome for patients with heart failure.
Objective
Heart failure (HF) is a chronic condition which tremendously impacts the life quality and expectancy of the patient as well as the healthcare system. The main responsible are acute episodes of decompensation, which are difficult to promptly detect because signs and symptoms occur late in the process. It was previously proved that changes in the hemodynamic parameters anticipate acute episodes by weeks, and their monitoring could be leveraged to predict and prevent the episode itself. Nevertheless, at date, this can only be performed via invasive sensors, which limit the target population to patients with severe HF. SoundTrack-HF targets this gap in the technology for HF monitoring.
The goal of SoundTrack-HF is to design, implement and validate an end-to-end system for the non-invasive monitoring of the status of compensation of HF patients using heart sounds (HS).
The project grounds on the use of a novel prototype enabling the self-recording of HS by the patient in a homecare setting. Cross-sectional and longitudinal data will be obtained from HF patients at their domicile. Time-related biomarkers related to the hemodynamic functionality will be extracted from the signals and validated against a gold standard (echocardiography). On one side, the patho-physiological spatio-temporal changes in the parameters will be modelled and interpreted in relation to the status of compensation of the patient. On the other side, an explainable AI-based acute episode predictor will be developed and used to extract novel knowledge about the relationship between HS and HF. At the end, signal- and AI-extracted knowledge will be integrated into a final predictor.
SoundTrack-HF is a highly interdisciplinary project. Its innovation resides in the development and validation of groundbreaking algorithmic solutions which, by leveraging a completely novel hardware, will disrupt the standard practice in auscultation and move it to the next level for domicile monitoring.
Fields of science (EuroSciVoc)
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CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
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Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
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(opens in new window) HORIZON-MSCA-2024-PF-01
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9220 Aalborg
Denmark
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