Objective
Glucose repression in yeast represents a major problem for both the cultivation on industrial substrates and for the breadmaking (leavening) because glucose has to be depleted before the remaining sugars can be utilized. In glucose-derepressed Saccharomyces cerevisiae strains, simultanous, and concomitantly more time-efficient, utilisation of the sugars would be possible resulting in an improved process economy and a lower environmental burden beside better leavening characteristics. Several genes playing key roles in catabolite repression have been deleted in an industrial strain. The physiology of the recombinants will be compared with the wild type in well controlled high performance bioreactors in order to elucidate the respective gene functions in the regulatory cascade of catabolite repression. Measurements of extracellular sugars and metabolites, assays for sugar-cleavaging enzymes and uptake systems, Northern blotting and radioactive techniques will be the analytical tools providing the basis for a metabolic flux analysis.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology environmental biotechnology bioremediation bioreactors
- medical and health sciences basic medicine physiology
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
2800 LYNGBY
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.