Skip to main content
DeutschDE
European Commission logo print header

Targeting astrocytes to disrupt inflammation-neurodegeneration coupling : application to alzheimer 's disease

Ziel

Increasing evidence supports the" inflammatory hypothesis in AD" according to which neuronal damages in this age-related disease are caused not only by the fundamental pathology but also by the local inflammatory response to it sustained by reactive glib. Recent findings demonstrate a sophisticated integration between neurons and atrocities. Inflammatory atrocities undergo morph functional changes, which may perturb neuron-atrocity interaction and result in neuronal sufferance. By identifying and targeting harmful pathways in inflammatory atrocities we will define potential new therapeutic approaches to prevent or delay AD progression. This consortium combines complementary expertise to: a) assess the "inflammatory hypothesis of AD" and the role of atrocities in transgenic models; b) identify targets of inflammation-neurodegeneration coupling in atrocities; c) validate drug strategies against them; d) test these therapeutically strategies in AD transgenic.

Wissenschaftliches Gebiet

Programm/Programme

Thema/Themen

Aufforderung zur Vorschlagseinreichung

Data not available

Finanzierungsplan

CSC - Cost-sharing contracts

Koordinator

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
EU-Beitrag
Keine Daten
Adresse
Rue de Tolbiac, 101
75654 PARIS
Frankreich

Auf der Karte ansehen
Gesamtkosten
Keine Daten

Beteiligte (6)

Diese Seite teilen

Herunterladen

Letzte Aktualisierung: 12 April 2005

Mein Booklet

Permalink: https://cordis.europa.eu/project/id/QLK6-CT-1999-02203/de

European Union, 2024