Objective The study aims to evaluate:(a) the association between 15 month IMT-progression of carotid artery and the rate of vascular events (from the 15th to the 36th month of follow up) in subjects at high risk of atherosclerosis and (b) the association between cross-sectional carotid arteries IMT and the rate of vascular events. The effect of gene polymorphisms, lipid peroxidation, socio-economic and psychological variables on the same ultrasonographic end points will be also assessed. In addition, the study will: (a)standardize at EU level an ultrasound scan and reading protocol to be used in future clinical trials; (b)compare the genetic and ultrasonic characteristics of patients from north and south Europe;(c) assess the impact of an early detection of atherosclerotic disease on the patients quality of life and(d) its economic consequences.Data will be analysed with conventional statistic vs. an innovative approach based on artificial neural networks. Fields of science medical and health sciencesclinical medicinecardiologycardiovascular diseasesarteriosclerosisnatural sciencesbiological sciencesbiochemistrybiomoleculeslipidsnatural sciencesphysical sciencesacousticsultrasoundnatural sciencescomputer and information sciencesartificial intelligencecomputational intelligence Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator THE UNIVERSITY OF MILANO EU contribution No data Address Via Balzaretti 9 20133 MILANO Italy See on map Total cost No data Participants (10) Sort alphabetically Sort by EU Contribution Expand all Collapse all ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS France EU contribution No data Address Boulevard de l'Hopital 47-83 75651 PARIS See on map Total cost No data BRACCO IMAGING S.P.A Italy EU contribution No data Address Via Egidio Folli, 50 20134 MILANO See on map Total cost No data CENTRO CARDIOLOGICO MONZINO SPA Italy EU contribution No data Address Via Filodrammatici, 10 20122 MILANO See on map Total cost No data CFCONSULTING FINAZIAMENTI UNIONE EUROPEA S.R.L Italy EU contribution No data Address Via Giuseppe Mussi, 1 20154 MILANO See on map Total cost No data FOUNDATION FOR RESEARCH IN HEALTH EXERCISE AND NUTRITION Finland EU contribution No data Address Haapaniementie 16 KUOPIO See on map Links Website Opens in new window Total cost No data KAROLINSKA INSTITUTE Sweden EU contribution No data Address Karolinska Hospital 17116 STOCKHOLM See on map Total cost No data UNIVERSITA DEGLI STUDI DI PERUGIA Italy EU contribution No data Address Via Brunamonti, 51 06122 PERUGIA See on map Total cost No data UNIVERSITY COLLEGE LONDON United Kingdom EU contribution No data Address University Street 5 WC1E 6JJ London See on map Total cost No data UNIVERSITY OF GRONINGEN Netherlands EU contribution No data Address Hanzeplein 1 9700 RB GRONINGEN See on map Total cost No data UNIVERSITY OF KUOPIO Finland EU contribution No data Address Harjulantie 1 B 70211 KUOPIO See on map Total cost No data