Obiettivo Mental retardation (MR) is a highly heterogeneous disorder and is of genetic origin in about 50% of the cases. Despite recent progress in research the causes and the pathophysiology of MR remains obscure. It is essential to investigate this in order to develop future diagnostic and therapeutic strategies. The overall goal of this proposal is to establish an interdisciplinary Eastern Europe and Central Asia (EECA) consortium of experts with a joint programme of activities to generate knowledge about MR and the structure and dynamics of the brain as such. This project will be the first to study in depth the prevalence and incidence of MR in EECA . The objectives of the CHERISH project are to: - to develop a standardized approach for MR diagnosis through clinical workshops and courses - to create a large data-base of patients with clinically well defined MR, both syndromic and non-syndromic - identify cryptic genomic rearrangements through molecular cytogenetic analysis - sequence MR genes and analyse the molecular epidemiology of MR in Eastern European populations - develop diagnostic tools for recurrent/common mutations - identify new MR genes in X-linked and autosomal recessive forms of the disorder - increase awareness on the possible genetic origin of MR and implications for novel therapeutic strategies The project partners will join forces to create a large collection of samples and a database from MR patients which will be become the reference. All institutions involved are the referral centres for MR in their respective countries. The molecular studies will be performed in technologically-advanced genetic laboratories. A straightforward outcome of CHERISH will lay the basis for a significant improvement of clinical, educational and industrial developments. The project will contribute to improve the management of MR with the potential to reduce the high health care costs and to improve quality of life of the concerned population. Campo scientifico natural sciencescomputer and information sciencesdatabasesmedical and health scienceshealth sciencespublic healthepidemiologymedical and health sciencesbasic medicinephysiologypathophysiologynatural sciencesbiological sciencesgeneticsmutation Parole chiave Adolescence Children Eastern Europe Central Asia Genetics Genomics Mental retardation Programma(i) FP7-HEALTH - Specific Programme "Cooperation": Health Argomento(i) HEALTH-2007-2.2.1-10 - Childhood and adolescent mental disorders Invito a presentare proposte FP7-HEALTH-2007-B Vedi altri progetti per questo bando Meccanismo di finanziamento CP-SICA - Collaborative project for specific cooperation actions dedicated to international cooperation partner countries (SICA) Coordinatore ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA Contributo UE € 800 737,49 Indirizzo VIA ZAMBONI 33 40126 Bologna Italia Mostra sulla mappa Regione Nord-Est Emilia-Romagna Bologna Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Verdiana Bandini (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (10) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto TARTU ULIKOOL Estonia Contributo UE € 323 379,00 Indirizzo ULIKOOLI 18 51005 Tartu Mostra sulla mappa Regione Eesti Eesti Lõuna-Eesti Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Merike Leego (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato VILNIAUS UNIVERSITETAS Lituania Contributo UE € 192 080,00 Indirizzo UNIVERSITETO G. 3 01513 Vilnius Mostra sulla mappa Regione Lietuva Sostinės regionas Vilniaus apskritis Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Vida Lapinskaite (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERZITA KARLOVA Cechia Contributo UE € 171 520,00 Indirizzo OVOCNY TRH 560/5 116 36 Praha 1 Mostra sulla mappa Regione Česko Praha Hlavní město Praha Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Renata Bourahi (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU Polonia Contributo UE € 151 996,00 Indirizzo UL. FREDRY 10 61-701 Poznan Mostra sulla mappa Regione Makroregion północno-zachodni Wielkopolskie Miasto Poznań Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Magdalena Badura-Stronka (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato INSTYTUT MOLEKULYARNOI BIOLOGII I GENETYKY NAN UKRAINY Ucraina Contributo UE € 168 815,00 Indirizzo ZABOLOTNOGO STREET 150 03680 Kyiv Mostra sulla mappa Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Yaroslav Korpan (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato KYPRIAKO IDRYMA EREVNON GIA TI MYIKI DISTROFIA Cipro Contributo UE € 319 652,00 Indirizzo 6 IROON AVENUE 2371 AGIOS DOMETIOS Mostra sulla mappa Regione Κύπρος Κύπρος Κύπρος Tipo di attività Research Organisations Contatto amministrativo Marios Flouros (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato NII MEDICINSKOY GENETIKI TOMSKOGO NAUCHNOGO CENTRA SIBIRSKOGO OTDELENIYA ROSSIYSKOY AKADEMII MEDICINSKIH NAUK Russia Contributo UE € 203 440,00 Indirizzo NABEREZHNAYA USHAYKI 10 634050 TOMSK Mostra sulla mappa Tipo di attività Research Organisations Contatto amministrativo Valery Puzyrev (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Center of Medical Genetics and Primary Health Care Armenia Contributo UE € 140 200,00 Indirizzo ZAKIYAN STREET 5/1 375010 Yerevan Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Hovhannes Hovhannisyan (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Costo totale Nessun dato MOLECULAR STAMPING SRL Partecipazione conclusa Italia Contributo UE € 51 580,51 Indirizzo Via Manzoni 16 38100 TRENTO Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Alberto Durante (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato FONDAZIONE EUROPEA PER LA GENETICA Italia Contributo UE € 123 811,00 Indirizzo VIA DI GAIBOLA 16 40136 BOLOGNA Mostra sulla mappa Tipo di attività Research Organisations Contatto amministrativo Michele Zadra (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
