Project description
Microsystems and Smart Miniaturised Systems
Analysis of biological cells down to single cell resolution is a prospective technique in nearly all fields of life science research. In particular manipulation and analysis of single cells can open up a new dimension in cell biology, tissue engineering, drug development and diagnostics. The advancement of single cell technology as a whole requires tools and instrumentation to sort, transport and manipulate single living cells. Micro system technology with its sophistications can provide in this context capabilities far beyond today's methods.
Therefore, this project aims to develop a single cell manipulator (SCM) micro instrument for inkjet like printing of single living cells confined in micro droplets of only 50µm size. Such a device can serve as a universal tool for manipulating cells in a non-invasive flexible manner. Within the project the SCM device will be applied to cell biological applications in cancer research and drug development to demonstrate and validate the performance of the device, as well as to establish a flexible platform for advanced single cell-manipulation and analysis (PASCA).
In order to achieve these objectives crosscutting technological challenges have to be faced which can be overcome by integrating and interfacing multiple core technologies, only. Cutting edge bio-sensing technology like impedance spectroscopy and state of the art micro dispensing methods will be applied and combined with latest cell biological methods to establish the SCM instrument as multifunctional microsystem for cell manipulation. Through the highly innovative integrated approach and the validation within the PASCA platform the SCM instrument has excellent exploitation perspectives in multiple application sectors.
Also the project structure as a whole supports the objectives of the work program:By intensively involving SMEs to feed the innovation cycle and by bringing the user into research cycles through the open access partner structure.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- engineering and technologyenvironmental biotechnologybiosensing
- natural sciencesbiological sciencescell biology
- medical and health sciencesmedical biotechnologytissue engineering
- medical and health sciencesmedical biotechnologycells technologies
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Call for proposal
FP7-ICT-2009-5
See other projects for this call
Funding Scheme
CP - Collaborative project (generic)Coordinator
79098 Freiburg
Germany