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Content archived on 2024-05-30
Strengthening Regional Bioresearch Potential in Greece: Advanced scientific performance at the Department of Molecular Biology and Genetics in Thrace

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EU supports research infrastructure in Greece

European funding boosted research into human disease genetics at a Greek university in Thrace. Improved infrastructure coupled with scientific exchange should ensure a sustained presence of their molecular biology and genetics (MBG) department in the European research community.

The BIOSTRENGTH (Strengthening regional bioresearch potential in Greece: Advanced scientific performance at the department of molecular biology and genetics in Thrace) project was a regional effort of the Democritus University of Thrace in Greece to enhance scientific performance of their MBG department. The only faculty in Greece providing a curriculum specialised in molecular biology and genetics, MBG also excels in basic research. BIOSTRENGTH funding contributed towards the development of a strong technological basis for concrete research facilities and infrastructure. The ultimate goal was to enhance the research and development (R&D) capacity of the department and foster collaborations that would serve MBG's vision of becoming a centre of research excellence in south-east Europe. MBG set up and is currently operating the Cell Imaging and Biomolecular Interactions (CiBIT) core facility, which focuses on the areas of bioimaging and biomolecular interaction analysis. CiBIT is equipped with state-of-the-art equipment, a customised multi-laser line modular confocal microscope, and a multiplex surface plasmon resonance (SPR) biosensor. The unit operates internal and external services, providing advanced cellular imaging and characterisation of in vitro macromolecular and target-drug interactions with support from dedicated scientific staff of international expertise. Short-term exchanges with institutions throughout Europe have enhanced dynamic research and training. The main knowledge transfer network participants were the Advanced Light Microscopy Facility of EMBL-Heidelberg, the Technology Facility of the University of York, Friedrich Miescher Institute of Novartis Research Foundation-Basel and the Center of Genetic Research, Barcelona. Dissemination was a key activity throughout the BIOSTRENGTH project and included publications in peer-reviewed journals and conferences. CiBIT's infrastructure and training capacity was demonstrated through the organisation of a 'Biomolecular Interactions' workshop. The workshop focused on the use of SPR technology for the qualitative and quantitative analysis of molecular systems. The BIOSTRENGTH project has fostered strategic partnerships with academia, research institutes and industry. Ranging from life science research and diagnostics to microscopy, imaging and high-tech cameras, applications for deliverables will span many life sciences fields. Long-term, MBG participation at national and international levels should grow to attract future EU funding and participation in research consortia.

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