Deliverables Documents, reports (7) Report on LCA and LCC: Baseline scope, functional units definition and database review Baseline scope functional units definition and database review to assess both the environmental impacts and the capital operational costs and costs reductions of SECRETed innovative biotechnological value chain for biosurfactants and siderophores production First report on phylogenetic tree database for siderophore and biosurfactant biosynthetic gene clusters and enzymes and their reactions. Public available siderophore and biosurfactant biosynthetic gene clusters and enzymes and their reactions will be delivered after identifying Key Exploitable Results KERs which will be described later in the interim PEDR D82 in M18 Protocols Handbook for chemical characterization and preparatory techniques. Besides previous approaches conducted by consortium members PHM SZN and MATIS will guide the preparation of standardized methods on sample processing and sharing This is crucial since samples from cultures clones or pool of clones and any extractsfractions containing traces of siderophore or surfactant activity need to be properly standardized to ensure the good progress of the project This will ultimately lead the development of a Handbook for chemical characterization and preparatory techniques D21 on month M6 and is closely related to deliverables envisaged in Tasks 5154 The Handbook will be revised and updated within WP5 activities First report on SECRETed Molecular Networks: Publicly available molecular structures and inference of associated features to molecular fingerprints Public available molecular structures and the inference of associated features to molecular fingerprints will be delivered after identifying Key Exploitable Results KERs which will be described later in the interim PEDR D82 in M18 Final report on phylogenetic tree database for siderophore and biosurfactant biosynthetic gene clusters containing novel enzymes and their reactions. Public available siderophore and biosurfactant biosynthetic gene clusters and enzymes and their reactions will be delivered after identifying Key Exploitable Results KERs which will be described later in the interim PEDR D82 in M36 Protocols Handbook of screening procedures for extremophilic microorganisms PHM ADL LUND MATIS USE and SZN will work together on the development of a standardized screening pipeline which will be applied to evaluate the potential of all the project microbial collections for the production of bioactive molecules This will allow the reproducibility of the results in the biodiscovery of new biosurfactants and siderophores A single deliverable D22 on month M6 will be achieved by reporting a Protocols Handbook of screening procedures for marine and extremophilic microorganisms Final report on SECRETed Molecular Networks: New molecular structures and associated features to molecular fingerprints. Public available molecular structures and the inference of associated features to molecular fingerprints will be delivered after identifying Key Exploitable Results KERs which will be described later in the interim PEDR D83 in M36 Websites, patent fillings, videos etc. (1) Project website and social media presence The website will contain a brief presentation of the project goals and objectives along with a brief description of the consortium and the implemented work strategy It will serve as the major source of information for the public regarding updates achievements and activitiesAs a result the website will be continuously updated with any relevant updateSocial media accounts for the direct promotion of SECRETed will be set up These accounts will be active in both professional networks eg LinkedIn and publicsocial networks eg Facebook Twitter enabling the projects communication to be as broad as possible Active and continuous online presence can be ensured with the social media accounts providing direct measurements on the interested audience and its engagement rate Publications Peer reviewed articles (11) Medium development and production of carotenoids and exopolysaccharides by the extremophile Rhodothermus marinus DSM16675 in glucose-based defined media Author(s): Israt Jahan Mukti; Roya R. R. Sardari; Thordis Kristjansdottir; Gudmundur O. Hreggvidsson; Eva Nordberg Karlsson Published in: Microbial Cell Factories, Issue 14752859, 2022, ISSN 1475-2859 Publisher: BioMed Central DOI: 10.1186/s12934-022-01946-7 Novel Insights on Pyoverdine: From Biosynthesis to Biotechnological Application Author(s): Filippo Dell'Anno; Giovanni Andrea Vitale; Carmine Buonocore; Laura Vitale; Fortunato Palma Esposito; Daniela Coppola; Gerardo Della Sala; Pietro Tedesco; Donatella de Pascale Published in: International Journal of Molecular Sciences, Issue 14220067, 2022, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms231911507 Combining OSMAC Approach and Untargeted Metabolomics for the Identification of New Glycolipids with Potent Antiviral Activity Produced by a Marine Rhodococcus Author(s): Palma Esposito, Fortunato; Giugliano, Rosa; Della Sala, Gerardo; Vitale, Giovanni Andrea; Buonocore, Carmine; Ausuri, Janardhan; Galasso, Christian; Coppola, Daniela; Franci, Gianluigi; Galdiero, Massimiliano; de Pascale, Donatella Published in: International Journal of Molecular Sciences, 2021, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms22169055 Applicability of Control Materials To Support Gene Promoter Characterization and Expression in Engineered Cells Using Digital PCR Author(s): Ana Fernandez-Gonzalez; Simon Cowen; Juhyun Kim; Carole A. Foy; Jose Jimenez; Jim F. Huggett Published in: Analytical Chemistry, 2022, ISSN 0003-2700 Publisher: American Chemical Society DOI: 10.1021/acs.analchem.1c05134 Evaluation of Antimicrobial Properties and Potential Applications of Pseudomonas gessardii M15 Rhamnolipids towards Multiresistant Staphylococcus aureus Author(s): Carmine Buonocore; Rosa Giugliano; Gerardo Della Sala; Fortunato Palma Esposito; Pietro Tedesco; Veronica FOLLIERO; Massimiliano Galdiero; Gianluigi Franci; Donatella de Pascale Published in: Pharmaceutics, 2023, ISSN 1999-4923 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics15020700 Water potential governs the effector specificity of the transcriptional regulator XylR of Pseudomonas putida Author(s): Pavel Dvořák; Teca Calcagno Galvão; Katharina Pflüger-Grau; Alice M. Banks; Víctor de Lorenzo; Jose I. Jiménez Published in: Environmental Microbiology, 2023, ISSN 1462-2920 Publisher: Applied Microbiology International DOI: 10.1111/1462-2920.16342 Production of selenium nanoparticles occurs through an interconnected pathway of sulphur metabolism and oxidative stress response in Pseudomonas putida KT2440 Author(s): Roberto Avendaño; Said Muñoz‐Montero; Diego Rojas‐Gätjens; Paola Fuentes‐Schweizer; Sofía Vieto; Rafael Montenegro; Manuel Salvador; Rufus Frew; Juhyun Kim; Max Chavarría; Jose I. Jiménez Published in: Microbial Biotechnology, 2023, ISSN 1751-7915 Publisher: John Wiley & Sons Ltd DOI: 10.1111/1751-7915.14215 Dihydroauroglaucin Isolated from the Mediterranean Sponge Grantia compressa Endophyte Marine Fungus Eurotium chevalieri Inhibits Migration of Human Neuroblastoma Cells Author(s): Marzia Vasarri, Giovanni Andrea Vitale, Giovanna Cristina Varese, Emanuela Barletta, Maria Valeria D’Auria, Donatella de Pascale and Donatella Degl’Innocenti Published in: Pharmaceutics, Issue 19994923, 2022, ISSN 1999-4923 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics14030616 Antiviral Activity of the Rhamnolipids Mixture from the Antarctic Bacterium Pseudomonas gessardii M15 against Herpes Simplex Viruses and Coronaviruses Author(s): Giugliano Rosa; Buonocore Carmine; Zannella Carla; Chianese Annalisa; Esposito Fortunato Palma; Tedesco Pietro; De Filippis Anna; Galdiero Massimiliano; Franci Gianluigi; de Pascale Donatella Published in: Pharmaceutics, 2021, ISSN 1999-4923 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics13122121 Prolonged Subculturing of Aspergillus fumigatus on Galleria Extract Agar Results in Altered Virulence and Sensitivity to Antifungal Agents Author(s): Aaron Curtis; KieranWalshe; Kevin Kavanagh Published in: Cells, 2023, ISSN 2073-4409 Publisher: MDPI DOI: 10.3390/cells12071065 MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters Author(s): Barbara Terlouw; Kai Blin; Jorge C. Navarro-Muñoz; Nicole E. Avalon; Marc Chevrette; Susan Egbert; Sanghoon Lee; David Meijer; Michael Recchia; Zachary L. Reitz; Jeffrey A. van Santen; Nelly Selem; Thomas Tørring; Liana Zaroubi; Mohammad Alanjary; Gajender Aleti; César Aguilar; Suhad Al-Salihi; Hannah E. Augustijn; J. Abraham Avelar-Rivas; Luis Alfredo Avitia Dominguez; Barona-Gomez F; Jordan B Published in: Nucleic Acids Research, 2023, ISSN 0305-1048 Publisher: Oxford University Press DOI: 10.1093/nar/gkac1049 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
