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Quantitative Investigation of Interspecies Differences in Developmental Tempo

Project description

It’s all about timing: the paradigm of embryonic development

Embryonic development begins after fertilisation and undergoes the same stages in many species, at however different paces depending on the organism. The underlying aetiology of the differences in developmental time between species remains unclear. The working hypothesis of the EU-funded ALLOCHRONY project is that this developmental allochrony is due to different rates in key biochemical reactions. Researchers will develop organoids from pluripotent stem cells that mimic early embryogenesis to study key reactions in mouse and human cells. Results will advance existing knowledge on embryonic development and identify the rate-limiting steps in the process.

Host institution

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Net EU contribution
€ 1 987 447,00
Address
Meyerhofstrasse 1
69117 Heidelberg
Germany

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Other funding
€ 0,00

Beneficiaries (1)

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
Net EU contribution
€ 1 987 447,00
Address
Meyerhofstrasse 1
69117 Heidelberg

See on map

Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Other funding
€ 0,00