Organic phases in cells: Elucidating the physical nature of biological liquid droplets

Información del proyecto

BlobMech

Identificador del acuerdo de subvención: 101002859

DOI

10.3030/101002859

Fecha de la firma de la CE 13 Abril 2021

Fecha de inicio 1 Septiembre 2021

Fecha de finalización 31 Agosto 2027

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 999 806,00

Aportación de la UE

€ 1 999 806,00

Coordinado por

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (12)

Posttranslational, site-directed photochemical fluorine editing of protein sidechains to probe residue oxidation state via 19F-nuclear magnetic resonance

Autores: Patrick G. Isenegger, Brian Josephson, Ben Gaunt, Matthew J. Davy, Veronique Gouverneur, Andrew J. Baldwin, Benjamin G. Davis
Publicado en: Nature Protocols, Edición 18, 2023, Página(s) 1543-1562, ISSN 1754-2189
Editor: Nature Publishing Group
DOI: 10.1038/s41596-022-00800-9

Uncovering the Role of <i>N</i>-Glycan Occupancy on the Cooperative Assembly of Spike and Angiotensin Converting Enzyme 2 Complexes: Insights from Glycoengineering and Native Mass Spectrometry

Autores: El-Baba, TJ; Lutomski, CA; Burnap, SA; Bolla, JR; Baker, LA; Baldwin, AJ; Struwe, WB; Robinson, CV
Publicado en: Crossref, Edición 2, 2023, ISSN 1520-5126
Editor: ACS Publications
DOI: 10.1021/jacs.3c00291

UnidecNMR: automatic peak detection for NMR spectra in 1-4 dimensions

Autores: Charles Buchanan, Gogulan Karunanithy, Olga Tkachenko, Michael Barber, Michael T. Marty, Timothy J. Nott, Christina Redfield, Andrew J. Baldwin
Publicado en: Nature Communications, Edición 16, 2025, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-024-54899-3

Reductive site-selective atypical <i>C</i> , <i>Z</i> -type/N2-C2 cleavage allows C-terminal protein amidation

Autores: Mollner, TA; Giltrap, AM; Zeng, Y; Demyanenko, Y; Buchanan, C; Oehlrich, D; Baldwin, AJ; Anthony, DC; Mohammed, S; Davis, BG
Publicado en: Crossref, Edición 4, 2022, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abl8675

Small-molecule dissolution of stress granules by redox modulation benefits ALS models

Autores: Hiroyuki Uechi, Sindhuja Sridharan, Jik Nijssen, Jessica Bilstein, Juan M. Iglesias-Artola, Satoshi Kishigami, Virginia Casablancas-Antras, Ina Poser, Eduardo J. Martinez, Edgar Boczek, Michael Wagner, Nadine Tomschke, António M. de Jesus Domingues, Arun Pal, Thom Doeleman, Sukhleen Kour, Eric Nathaniel Anderson, Frank Stein, Hyun O. Lee, Xiaojie Zhang, Anatol W. Fritsch, Marcus Jahnel, Julius F
Publicado en: Nature Chemical Biology, Edición 21, 2025, Página(s) 1577-1588, ISSN 1552-4450
Editor: Nature Publishing Group
DOI: 10.1038/s41589-025-01893-5

Efficiently computing the Uhlmann fidelity for density matrices

Autores: Andrew J. Baldwin; Jonathan A. Jones
Publicado en: Crossref, Edición 1, 2023, ISSN 2469-9926
Editor: American Physical Society
DOI: 10.1103/physreva.107.012427

Poststranlational, site-directed photochemical fluorine editing of protein sidechains to probe residue oxidation state via 19F-nuclear magnetic resonance

Autores: Isenegger, Patrick G; Josephson, Brian; Gaunt, Ben; Davy, Matthew J; Gouverneur, Veronique; Baldwin, Andrew J; Davis, Benjamin G.
Publicado en: natureprotocols, 2023, ISSN 1754-2189
Editor: Nature Publishing Group
DOI: 10.1038/s41586-020-2733-7

Ion binding with charge inversion combined with screening modulates DEAD box helicase phase transitions

Autores: Crabtree MD, Hollan J, Pillai AS, Kompella PS, Babl Leon, Turner Noah, Eaton James, Hochberg GKA, Aarts Dirk, Redfield Christina, Baldwin AJ, Nott Timothy
Publicado en: Cell Reports, 2023, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2023.113375

Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted

Autores: Lachlan P. Deimel, Lucile Moynié, Guoxuan Sun, Viliyana Lewis, Abigail Turner, Charles J. Buchanan, Sean A. Burnap, Mikhail Kutuzov, Carolin M. Kobras, Yana Demyanenko, Shabaz Mohammed, Mathew Stracy, Weston B. Struwe, Andrew J. Baldwin, James Naismith, Benjamin G. Davis, Quentin J. Sattentau
Publicado en: Nature Communications, Edición 15, 2024, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-024-51138-7

Biocatalytic reductive amination as a route to isotopically labelled amino acids suitable for analysis of large proteins by NMR

Autores: Rowbotham, JS; Nicholson, JH; Ramirez, MA; Urata, K; Todd, PMT; Karunanithy, G; Lauterbach, L; Reeve, HA; Baldwin, AJ; Vincent, KA
Publicado en: Rowbotham , J , Nicholson , J , Hernandez , M R , Urata , K , Todd , P M T , Karunanithy , G , Lauterbach , L , Reeve , H , Baldwin , A & Vincent , K 2023 , ' Biocatalytic reductive amination as a route to isotopically labelled amino acids suitable for analysis of large proteins by NMR ' , Chemical Science , vol. 14 , no. 43 , pp. 12160-12165 . https://doi.org/10.1039/d3sc01718d, Edición 2, 2023, ISSN 2041-6539
Editor: RWTH Publications
DOI: 10.1039/d3sc01718d

Seedless: on-the-fly pulse calculation for NMR experiments

Autores: Charles J. Buchanan, Gaurav Bhole, Gogulan Karunanithy, Virginia Casablancas-Antràs, Adeline W. J. Poh, Benjamin G. Davis, Jonathan A. Jones, Andrew J. Baldwin
Publicado en: Nature Communications, Edición 16, 2025, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-025-61663-8

Pathogen-sugar interactions revealed by universal saturation transfer analysis

Autores: Charles Buchanan, Ben Gaunt, Peter Harrison, Yun Yang, Jiwei Liu, Aziz Khan, Andrew Giltrap, Audrey Le Bas, Philipp Ward, Kapil Gupta, Maud Dumoux, Tiong Kit Tan, Lisa Schimaski, Sergio Daga, Picchiotti Nicola, Margherita Baldassarri, Elisa Benetti, Chiara Fallerini, Francesca Fava, Annarita Giliberti, Panagiotis Koukos, Matthew Davy, Abirami Lakshminarayanan, Xiaochao Xue, Georgios Papadakis, Lac
Publicado en: Science, 2022, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.abm3125

Thesis and dissertations (1)

Mechanistic insights on protein aggregation and phase separation

Autores: Casablancas Antràs, V
Publicado en: Thesis, Edición 1, 2023, Página(s) All
Editor: University of Oxford
DOI: 10.5287/ora-qq77bd2gy