FIGHTING-OFF CORONAVIRUS (SARS-CoV-2) WITH BROAD-SPECTRUM ANTIVIRALS: ESTABLISHING ANIMAL VIRAL CHALLENGE MODEL

Project description

New intranasal drugs against SARS-CoV-2

The extent of the current COVID-19 pandemic demands concerted efforts towards effective diagnostics, therapies and vaccines. In this direction, the EU-funded Fight-nCoV project will accelerate the preclinical development of new broad-spectrum antivirals administered via inhalation. The work builds on ongoing research on drugs that block viral entry and will test their safety and activity against SARS-CoV-2 in a macaque model of the disease. The efficacy information on these intranasal inhibitors in non-human primates will lay the foundation for the next step in the development pipeline of these drugs for human use.

Fields of science

• medical and health sciences › health sciences › infectious diseases › RNA viruses › coronaviruses

Programme(s)

• H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme
• H2020-EU.3.1.3. - Treating and managing disease

Topic(s)

• SC1-PHE-CORONAVIRUS-2020 - Advancing knowledge for the clinical and public health response to the 2019-nCoV epidemic

Call for proposal

H2020-SC1-PHE-CORONAVIRUS-2020

See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

STOCKHOLMS UNIVERSITET

Net EU contribution

€ 842 937,50

Address

Universitetsvagen 10
10691 Stockholm
Sweden

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

Östra Sverige › Stockholm › Stockholms län

Participants (5)

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

France

Net EU contribution

€ 674 000,00

Address

Rue Leblanc 25
75015 Paris 15

Activity type

Research Organisations

Non-EU contribution

€ 0,00

Region

Ile-de-France › Ile-de-France › Paris

UNIVERSITAET ULM

Germany

Net EU contribution

€ 360 000,00

Address

Helmholtzstrasse 16
89081 Ulm

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

Baden-Württemberg › Tübingen › Ulm, Stadtkreis

AARHUS UNIVERSITET

Denmark

Net EU contribution

€ 144 226,25

Address

Nordre Ringgade 1
8000 Aarhus C

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

Østjylland › Midtjylland

ADLEGO BIOMEDICAL AB

Sweden

Net EU contribution

€ 620 588,50

SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes

Address

Box 42
751 03 Uppsala

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

Non-EU contribution

€ 0,25

Region

Östra Sverige › Östra Mellansverige › Uppsala län

UNIVERSITAET DUISBURG-ESSEN

Germany

Net EU contribution

€ 165 273,75

Address

Universitatsstrasse 2
45141 Essen

Activity type

Higher or Secondary Education Establishments

Non-EU contribution

€ 0,00

Region

Nordrhein-Westfalen › Düsseldorf › Essen, Kreisfreie Stadt