Project description
Keeping Europe at the forefront of molecular-scale biophysics
EU-funded MOSBRI, an integrated consortium of 13 academic centres of excellence and two industrial partners from 11 European countries, will spearhead the study of the architecture, dynamics and interactions of the giant molecules of life: proteins, DNA, RNA, polysaccharides and lipids. MOSBRI will explore how living organisms work at the crucial intermediate level between atomic-resolution structural descriptions and cellular-scale observations, enabling invaluable insights into the complex behaviour of macromolecular assemblies. MOSBRI will design innovative methodologies and quality control guidelines, provide free of charge access for to MOSBRI’s unparalleled suite of instruments and expertise, and widely disseminate know-how about the latest technological developments. Overall, it will help maintain Europe's role as a global leader in the field of molecular biophysics.
Objective
The aim of the MOlecular-Scale Biophysics Research Infrastructure (MOSBRI) is to enable ambitious integrative multi-technological studies of biological systems at the crucial intermediate level between atomic-resolution structural descriptions and cellular-scale observations.
Its consortium of 2 companies and 13 academic centres of excellence from 11 countries gathers a wide complementary panel of cutting-edge instrumentation and expertise, leveraging barriers that currently hinder the optimal exploitation of molecular-scale biophysical approaches in the fields of biomedicine, biotechnology, biomaterials and beyond.
MOSBRI provides European academic and industrial researchers with a one-stop shop Trans-National Access to the latest technological developments in advanced spectroscopies, hydrodynamics, thermodynamics, real-time kinetics and single molecule approaches.
It will play a major role in standardization and policy-making in the field by: i) carrying out Joint Research Activities to develop innovative methodologies; ii) designing robust quality control guidelines and FAIR-compatible archiving formats and databases; iii) engaging with instrumentation, pharma, biotech and CRO SMEs.
Networking activities will multiply the impact of MOSBRI, by efficiently sharing and disseminating theoretical and practical knowledge through training events in Europe, contributing to: i) the emergence of a highly qualified new generation of scientists; ii) outreach to scientific communities currently unaware of the full potential of the integrated use of molecular-scale biophysics tools.
MOSBRI is complementary to related infrastructures including INSTRUCT-ERIC and iNEXT-Discovery, and will help creating a strong cross-fertilizing ecosystem with leveraging effects for European science. It represents a unique opportunity for Europe to remain at the forefront in this competitive field, thereby contributing significantly to the acceleration of discoveries beneficial for OneHealth.
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Funding Scheme
RIA - Research and Innovation actionCoordinator
75724 Paris
France
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Participants (17)
8000 Aarhus C
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1050 Bruxelles / Brussel
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16126 Genova
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
16163 Genova
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9712CP Groningen
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69117 Heidelberg
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581 83 Linkoping
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1000 Ljubljana
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WC1E 7HX London
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75794 Paris
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
13284 Marseille
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252 50 Vestec
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00185 Roma
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50009 Zaragoza
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WR14 1XZ Malvern
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
Participation ended
752 28 Uppsala
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15782 Santiago De Compostela
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.