Health Initiatives in Psoriasis and PsOriatic arthritis ConsoRTium European States

Resultado final

Harmonised WP3 dataset available
Clinical characteristics associated with structural and functional progression
HPOS: First study subject approvals package

HPOS Prior to enrolment of first study subject i Final version of study protocol as submitted toregulatorsethics committees ii Registration number of clinical study in a WHOor ICMJE approvedregistry with the possibility to post results iii Approvals ethics committees and national competentauthority if applicable required for invitationenrolment of first subject in at least one clinical centre

Establishing HPOS

Public project website
Communication Concept Plan

Publicaciones

Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography

Autores: Tascilar K, Fagni F, Kleyer A, Bayat S, Heidemann R, Steiger F, Krönke G, Bohr D, Ramming A, Hartmann F, Klett D, Federle A, Regensburger AP, Wagner AL, Knieling F, Neurath MF, Schett G, Waldner M, Simon D.
Publicado en: Rheumatology (oxford), 2023, ISSN 1462-0332
Editor: Oxford University Press
DOI: 10.1093/rheumatology/keac346

DeepNAPSI multi-reader nail psoriasis prediction using deep learning

Autores: Lukas Folle, Pauline Fenzl, Filippo Fagni , Mareike Thies, Vincent Christlein, Christine Meder , David Simon , Ioanna Minnopoulou , Michael Sticherling , Georg Schett , Andreas Maier, Arnd Kleyer
Publicado en: Scientific Reports, 2023, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-023-32440-8

"Deep Learning-Based Classification of Inflammatory Arthritis by Identification of Joint Shape Patterns-How Neural Networks Can Tell Us Where to ""Deep Dive"" Clinically."

Autores: Lukas Folle; David Simon; Koray Tascilar; Gerhard Krönke; Anna-Maria Liphardt; Andreas Maier; Georg Schett; Arnd Kleyer
Publicado en: Frontiers in Medicine, Edición 3, 2022, ISSN 0003-4967
Editor: BMJ Publishing Group
DOI: 10.3389/fmed.2022.850552

Small molecule biomarker discovery: Proposed workflow for LC-MS-based clinical research projects

Autores: S. Rischke, L. Hahnefeld, B. Burla, F. Behrens, R. Gurke, T.J. Garrett
Publicado en: Journal of Mass Spectrometry and Advances in the Clinical Lab, Edición Volume 28, April 2023, 2023, Página(s) 47-55, ISSN 2667-145X
Editor: Elevier B.V.
DOI: 10.1016/j.jmsacl.2023.02.003

Pre-analytical sample handling standardization for reliable measurement of metabolites and lipids in LC-MS-based clinical research

Autores: A. Sens, S. Rischke, L. Hahnefeld, E. Dorochow, S.M.G. Schäfer, D. Thomas, M. Köhm, G. Geisslinger, F. Behrens, R. Gurke,
Publicado en: Journal of Mass Spectrometry and Advances in the Clinical Lab, Edición Volume 28, April 2023, 2023, Página(s) 35-46, ISSN 2667-145X
Editor: Elsevier B.V.
DOI: 10.1016/j.jmsacl.2023.02.002

OMICS and multi‐OMICS analysis for the early identification and improved outcome of patients with psoriatic arthritis

Autores: """Robert Gurke 1,2,3,*, Annika Bendes 4, John Bowes 5,6, Michaela Koehm 1,2,7, Richard M Twyman 8, Anne Barton 5,6, 4 Carl Goodyear 9, Lisa Hahnefeld 1,2,3, Rainer Hillenbrand 10, Ewan Hunter 11, Mark Ibberson 12, Vassilios Ioannidis 12, 5 Sabine Kugler 2,13, Eduard Resch 1,2, Stefan Rüping 2,13, Klaus Scholich 1,2,3, Jochen M Schwenk 4, James C 6 Waddington 14, Phil Whitfield 15, Gerd Geißlinger"
Publicado en: Biomedicines, 2023, ISSN 2227-9059
Editor: MDPI
DOI: 10.3390/biomedicines10102387

Sequential interleukin-17/interleukin-23 inhibition in treatment-refractory psoriatic arthritis

Autores: David Simon, Filippo Fagni, Georg Schett
Publicado en: Ann Rheum Dis, 2022, ISSN 1468-2060
Editor: BMJ Publishing group
DOI: 10.1136/annrheumdis-2022-222415

Concise report: a minimal-invasive method to retrieve and identify entheseal tissue from psoriatic arthritis patients

Autores: Pachowsky ML, Raimondo MG, Xu C, Rauber S, Tascilar K, Labinsky H, Vogg M, Aziz Saad MS, Simon D, Rech J, Soare A, Braeuer L, Kleyer A, Schett G, Ramming A.
Publicado en: Ann Rheum Dis, 2021, ISSN 0003-4967
Editor: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2021-222061

HIPPOCRATES: improving diagnosis and outcomes in psoriatic arthritis.

Autores: FitzGerald, O., Pennington, S.R.
Publicado en: Nature Reviews Rheumatology, Edición 18 (3), 2022, ISSN 1759-4804
Editor: Nat Rev Rheumatol
DOI: 10.1038/s41584-022-00748-w

Advanced neural networks for classification of MRI in psoriatic arthritis, seronegative, and seropositive rheumatoid arthritis

Autores: Lukas Folle; Sara Bayat; Arnd Kleyer; Filippo Fagni; Lorenz A Kapsner; Maja Schlereth; Timo Meinderink; Katharina Breininger; Koray Tascilar; Gerhard Krönke; Michael Uder; Michael Sticherling; Sebastian Bickelhaupt; Georg Schett; Andreas Maier; Frank Roemer; David Simon
Publicado en: Rheumatology, Edición 4, 2022, ISSN 1462-0332
Editor: BMJ Publishing group
DOI: 10.1093/rheumatology/keac197

Impact of Cytokine Inhibitor Therapy on the Prevalence, Seroconversion Rate, and Longevity of the Humoral Immune Response Against SARS?CoV-2 in an Unvaccinated Cohort

Autores: David Simon, Koray Tascilar, Arnd Kleyer, Filippo Fagni, Gerhard Krönke, Christine Meder, Peter Dietrich, Till Orlemann, Thorsten Kliem, Johanna Mößner, Anna-Maria Liphardt, Verena Schönau, Daniela Bohr, Louis Schuster, Fabian Hartmann, Moritz Leppkes, Andreas Ramming, Milena Pachowsky, Florian Schuch, Monika Ronneberger, Stefan Kleinert, Axel J. Hueber, Karin Manger, Bernhard Manger, Raja Atr
Publicado en: Arthritis & Rheumatology, 2022, ISSN 2326-5205
Editor: John Wiley & Sons (Wiley)
DOI: 10.1002/art.42035

Characterization of Serum and Mucosal SARS-CoV-2-Antibodies in HIV-1-Infected Subjects after BNT162b2 mRNA Vaccination or SARS-CoV-2 Infection

Autores: Schmidt KG, Harrer EG, Tascilar K, Kübel S, El Kenz B, Hartmann F, Simon D, Schett G, Nganou-Makamdop K, Harrer T.
Publicado en: Viruses, 2022, ISSN 1999-4915
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v14030651

Effects of casirivimab/imdevimab on systemic and mucosal immunity against SARS-CoV-2 in B-cell depleted patients with autoimmune rheumatic diseases refractory to vaccination

Autores: Filippo Fagni, Katja Schmidt, Daniela Bohr, Larissa Valor-Méndez, Fabian Hartmann, Koray Tascilar, Karin Manger, Bernhard Manger, Arnd Kleyer, David Simon, Georg Schett and Thomas Harrer
Publicado en: RMD Open, 2022, ISSN 2056-5933
Editor: BMJ Publishing Group
DOI: 10.1136/rmdopen-2022-002323

Resultado final

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