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Health Initiatives in Psoriasis and PsOriatic arthritis ConsoRTium European States


Harmonised WP3 dataset available
Clinical characteristics associated with structural and functional progression
HPOS: First study subject approvals package

HPOS Prior to enrolment of first study subject i Final version of study protocol as submitted toregulatorsethics committees ii Registration number of clinical study in a WHOor ICMJE approvedregistry with the possibility to post results iii Approvals ethics committees and national competentauthority if applicable required for invitationenrolment of first subject in at least one clinical centre

Establishing HPOS


Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography

Autorzy: Tascilar K, Fagni F, Kleyer A, Bayat S, Heidemann R, Steiger F, Krönke G, Bohr D, Ramming A, Hartmann F, Klett D, Federle A, Regensburger AP, Wagner AL, Knieling F, Neurath MF, Schett G, Waldner M, Simon D.
Opublikowane w: Rheumatology (oxford), 2023, ISSN 1462-0332
Wydawca: Oxford University Press
DOI: 10.1093/rheumatology/keac346

DeepNAPSI multi-reader nail psoriasis prediction using deep learning

Autorzy: Lukas Folle, Pauline Fenzl, Filippo Fagni , Mareike Thies, Vincent Christlein, Christine Meder , David Simon , Ioanna Minnopoulou , Michael Sticherling , Georg Schett , Andreas Maier, Arnd Kleyer
Opublikowane w: Scientific Reports, 2023, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-023-32440-8

"Deep Learning-Based Classification of Inflammatory Arthritis by Identification of Joint Shape Patterns-How Neural Networks Can Tell Us Where to ""Deep Dive"" Clinically."

Autorzy: Lukas Folle; David Simon; Koray Tascilar; Gerhard Krönke; Anna-Maria Liphardt; Andreas Maier; Georg Schett; Arnd Kleyer
Opublikowane w: Frontiers in Medicine, Numer 3, 2022, ISSN 0003-4967
Wydawca: BMJ Publishing Group
DOI: 10.3389/fmed.2022.850552

Small molecule biomarker discovery: Proposed workflow for LC-MS-based clinical research projects

Autorzy: S. Rischke, L. Hahnefeld, B. Burla, F. Behrens, R. Gurke, T.J. Garrett
Opublikowane w: Journal of Mass Spectrometry and Advances in the Clinical Lab, Numer Volume 28, April 2023, 2023, Strona(/y) 47-55, ISSN 2667-145X
Wydawca: Elevier B.V.
DOI: 10.1016/j.jmsacl.2023.02.003

Pre-analytical sample handling standardization for reliable measurement of metabolites and lipids in LC-MS-based clinical research

Autorzy: A. Sens, S. Rischke, L. Hahnefeld, E. Dorochow, S.M.G. Schäfer, D. Thomas, M. Köhm, G. Geisslinger, F. Behrens, R. Gurke,
Opublikowane w: Journal of Mass Spectrometry and Advances in the Clinical Lab, Numer Volume 28, April 2023, 2023, Strona(/y) 35-46, ISSN 2667-145X
Wydawca: Elsevier B.V.
DOI: 10.1016/j.jmsacl.2023.02.002

OMICS and multi‐OMICS analysis for the early identification and improved outcome of patients with psoriatic arthritis

Autorzy: """Robert Gurke 1,2,3,*, Annika Bendes 4, John Bowes 5,6, Michaela Koehm 1,2,7, Richard M Twyman 8, Anne Barton 5,6, 4 Carl Goodyear 9, Lisa Hahnefeld 1,2,3, Rainer Hillenbrand 10, Ewan Hunter 11, Mark Ibberson 12, Vassilios Ioannidis 12, 5 Sabine Kugler 2,13, Eduard Resch 1,2, Stefan Rüping 2,13, Klaus Scholich 1,2,3, Jochen M Schwenk 4, James C 6 Waddington 14, Phil Whitfield 15, Gerd Geißlinger"
Opublikowane w: Biomedicines, 2023, ISSN 2227-9059
Wydawca: MDPI
DOI: 10.3390/biomedicines10102387

Sequential interleukin-17/interleukin-23 inhibition in treatment-refractory psoriatic arthritis

Autorzy: David Simon, Filippo Fagni, Georg Schett
Opublikowane w: Ann Rheum Dis, 2022, ISSN 1468-2060
Wydawca: BMJ Publishing group
DOI: 10.1136/annrheumdis-2022-222415

Concise report: a minimal-invasive method to retrieve and identify entheseal tissue from psoriatic arthritis patients

Autorzy: Pachowsky ML, Raimondo MG, Xu C, Rauber S, Tascilar K, Labinsky H, Vogg M, Aziz Saad MS, Simon D, Rech J, Soare A, Braeuer L, Kleyer A, Schett G, Ramming A.
Opublikowane w: Ann Rheum Dis, 2021, ISSN 0003-4967
Wydawca: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2021-222061

HIPPOCRATES: improving diagnosis and outcomes in psoriatic arthritis.

Autorzy: FitzGerald, O., Pennington, S.R.
Opublikowane w: Nature Reviews Rheumatology, Numer 18 (3), 2022, ISSN 1759-4804
Wydawca: Nat Rev Rheumatol
DOI: 10.1038/s41584-022-00748-w

Advanced neural networks for classification of MRI in psoriatic arthritis, seronegative, and seropositive rheumatoid arthritis

Autorzy: Lukas Folle; Sara Bayat; Arnd Kleyer; Filippo Fagni; Lorenz A Kapsner; Maja Schlereth; Timo Meinderink; Katharina Breininger; Koray Tascilar; Gerhard Krönke; Michael Uder; Michael Sticherling; Sebastian Bickelhaupt; Georg Schett; Andreas Maier; Frank Roemer; David Simon
Opublikowane w: Rheumatology, Numer 4, 2022, ISSN 1462-0332
Wydawca: BMJ Publishing group
DOI: 10.1093/rheumatology/keac197

Impact of Cytokine Inhibitor Therapy on the Prevalence, Seroconversion Rate, and Longevity of the Humoral Immune Response Against SARS?CoV-2 in an Unvaccinated Cohort

Autorzy: David Simon, Koray Tascilar, Arnd Kleyer, Filippo Fagni, Gerhard Krönke, Christine Meder, Peter Dietrich, Till Orlemann, Thorsten Kliem, Johanna Mößner, Anna-Maria Liphardt, Verena Schönau, Daniela Bohr, Louis Schuster, Fabian Hartmann, Moritz Leppkes, Andreas Ramming, Milena Pachowsky, Florian Schuch, Monika Ronneberger, Stefan Kleinert, Axel J. Hueber, Karin Manger, Bernhard Manger, Raja Atr
Opublikowane w: Arthritis & Rheumatology, 2022, ISSN 2326-5205
Wydawca: John Wiley & Sons (Wiley)
DOI: 10.1002/art.42035

Characterization of Serum and Mucosal SARS-CoV-2-Antibodies in HIV-1-Infected Subjects after BNT162b2 mRNA Vaccination or SARS-CoV-2 Infection

Autorzy: Schmidt KG, Harrer EG, Tascilar K, Kübel S, El Kenz B, Hartmann F, Simon D, Schett G, Nganou-Makamdop K, Harrer T.
Opublikowane w: Viruses, 2022, ISSN 1999-4915
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v14030651

Effects of casirivimab/imdevimab on systemic and mucosal immunity against SARS-CoV-2 in B-cell depleted patients with autoimmune rheumatic diseases refractory to vaccination

Autorzy: Filippo Fagni, Katja Schmidt, Daniela Bohr, Larissa Valor-Méndez, Fabian Hartmann, Koray Tascilar, Karin Manger, Bernhard Manger, Arnd Kleyer, David Simon, Georg Schett and Thomas Harrer
Opublikowane w: RMD Open, 2022, ISSN 2056-5933
Wydawca: BMJ Publishing Group
DOI: 10.1136/rmdopen-2022-002323

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