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ACADEMIA AND INDUSTRY UNITED INNOVATION AND TREATMENT FOR TUBERCULOSIS

Project description

New clinical trial design for tuberculosis drugs

As with many bacterial diseases, tuberculosis has been hit by drug resistance, threatening the efficacy of existing treatments. Although there are new drugs for clinical evaluation, testing the different combinations is time-consuming and requires a concerted effort. The EU-funded UNITE4TB project brings together experts in the field to design and set new standards for tuberculosis Phase II clinical trials. The team will take advantage of existing networks across continents to recruit patients in trials and introduce state-of-the-art microbiology methods and machine learning technologies. Data on biomarkers and clinical pharmacology will accompany the validation of the new drugs to ensure their subsequent success down the drug discovery pipeline.

Coordinator

STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
Net EU contribution
€ 64 968 756,75
Address
Geert Grooteplein 10 Zuid
6525 GA Nijmegen
Netherlands

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Region
Oost-Nederland Gelderland Arnhem/Nijmegen
Activity type
Higher or Secondary Education Establishments
Other funding
€ 64 968 756,75

Participants (31)

LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER
United Kingdom
Net EU contribution
€ 794 947,50
Address
Keppel Street
WC1E 7HT London

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
Other funding
€ 794 947,50
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Net EU contribution
€ 1 499 568,75
Address
Wellington Square University Offices
OX1 2JD Oxford

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 499 568,75
FORSCHUNGSZENTRUM BORSTEL
Germany
Net EU contribution
€ 3 312 102,50
Address
Parkallee 1-40
23845 Borstel

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Region
Schleswig-Holstein Schleswig-Holstein Segeberg
Activity type
Research Organisations
Other funding
€ 3 312 102,50
STICHTING LYGATURE
Netherlands
Net EU contribution
€ 2 274 497,50
Address
Jaarbeursplein 6
3521 AL Utrecht

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Utrecht Utrecht
Activity type
Other
Other funding
€ 2 274 497,50
UNIVERSITY OF LANCASTER
United Kingdom
Net EU contribution
€ 253 347,50
Address
Bailrigg
LA1 4YW Lancaster

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Region
North West (England) Lancashire Lancaster and Wyre
Activity type
Higher or Secondary Education Establishments
Other funding
€ 253 347,50
UNIVERSITY COLLEGE LONDON
United Kingdom
Net EU contribution
€ 2 994 251,25
Address
Gower Street
WC1E 6BT London

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
Other funding
€ 2 994 251,25
TASK FOUNDATION NPC
South Africa
Net EU contribution
€ 869 670,00
Address
M2 Karl Bremer Hospital Mike Pienaar Boulevard Belleville
7530 Cape Town

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Activity type
Other
Other funding
€ 869 670,00
UNIVERSITA VITA-SALUTE SAN RAFFAELE
Italy
Net EU contribution
€ 713 000,00
Address
Via Olgettina 58
20132 Milano

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Region
Nord-Ovest Lombardia Milano
Activity type
Higher or Secondary Education Establishments
Other funding
€ 713 000,00
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany
Net EU contribution
€ 1 775 000,00
Address
Ingolstadter Landstrasse 1
85764 Neuherberg

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Region
Bayern Oberbayern München, Landkreis
Activity type
Research Organisations
Other funding
€ 1 775 000,00
KONINKLIJKE NEDERLANDSE CENTRALE VERENIGING TOT BESTRIJDING DER TUBERCULOSE (KNCV)
Netherlands
Net EU contribution
€ 1 573 523,75
Address
Maanweg 174
2516 AB 'S Gravenhage

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Region
West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage
Activity type
Other
Other funding
€ 1 573 523,75
CRITICAL PATH INSTITUTE, LIMITED
Ireland
Net EU contribution
€ 2 387 091,25
Address
33 Sir John Rogerson's
2 Dublin

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Northern and Western Border
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 2 387 091,25
EUROPEAN LUNG FOUNDATION
United Kingdom
Net EU contribution
€ 230 375,00
Address
Glossop Road 442
S10 2PX Sheffield

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Region
Yorkshire and the Humber South Yorkshire Sheffield
Activity type
Other
Other funding
€ 230 375,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

LUNGS EUROPE
Belgium
Net EU contribution
€ 40 000,00
Address
Rue De Treves 49-51
1040 Brussels

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Other
Other funding
€ 40 000,00
INSTITUTO DE SAUDE PUBLICA DA UNIVERSIDADE DO PORTO
Portugal
Net EU contribution
€ 616 040,00
Address
Praca Gomes Teixeira - Edificio Gomes Teixeira
4050 290 Porto

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Continente Norte Área Metropolitana do Porto
Activity type
Research Organisations
Other funding
€ 616 040,00
THE UNIVERSITY OF LIVERPOOL
United Kingdom
Net EU contribution
€ 1 630 442,50
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool

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Region
North West (England) Merseyside Liverpool
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 630 442,50
INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT
France
Net EU contribution
€ 144 995,00
Address
Boulevard De Dunkerque 44 Cs 90009
13572 Marseille

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Region
Provence-Alpes-Côte d’Azur Provence-Alpes-Côte d’Azur Bouches-du-Rhône
Activity type
Research Organisations
Other funding
€ 144 995,00
UNIVERSITAET HAMBURG
Germany
Net EU contribution
€ 436 250,00
Address
Mittelweg 177
20148 Hamburg

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Region
Hamburg Hamburg Hamburg
Activity type
Higher or Secondary Education Establishments
Other funding
€ 436 250,00
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
United States
Net EU contribution
€ 1 500 100,00
Address
Franklin Street 1111 12 Floor
94607 Oakland Ca

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 500 100,00
GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT NON PROFIT ORGANISATION
United States
Net EU contribution
€ 1 393 765,00
Other funding
€ 1 393 765,00
FOUNDATION FOR INNOVATIVE NEW DIAGNOSTICS
Switzerland
Net EU contribution
€ 1 135 539,50
Address
Campus Biotech, Chemin Des Mines 9
1202 Geneve

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Region
Schweiz/Suisse/Svizzera Région lémanique Genève
Activity type
Other
Other funding
€ 1 135 539,50
UNIVERSITA DEGLI STUDI DI MILANO
Italy
Net EU contribution
€ 402 652,50
Address
Via Festa Del Perdono 7
20122 Milano

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Region
Nord-Ovest Lombardia Milano
Activity type
Higher or Secondary Education Establishments
Other funding
€ 402 652,50
THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS
United Kingdom
Net EU contribution
€ 633 985,00
Address
North Street 66 College Gate
KY16 9AJ St Andrews

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Region
Eastern Scotland Clackmannanshire and Fife
Activity type
Higher or Secondary Education Establishments
Other funding
€ 633 985,00
UPPSALA UNIVERSITET
Sweden
Net EU contribution
€ 446 286,25
Address
Von Kraemers Alle 4
751 05 Uppsala

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Region
Östra Sverige Östra Mellansverige Uppsala län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 446 286,25
EUROPEAN RESPIRATORY SOCIETY
Switzerland
Net EU contribution
€ 223 375,00
Address
Avenue Sainte Luce 4
1003 Lausanne

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Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Other
Other funding
€ 223 375,00
TUBERCULOSIS NETWORK EUROPEAN TRIALSGROUP EV
Germany
Net EU contribution
€ 250 437,50
Address
Armenberg 6
23843 Bad Oldesloe

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Region
Schleswig-Holstein Schleswig-Holstein Stormarn
Activity type
Research Organisations
Other funding
€ 250 437,50
GLAXOSMITHKLINE INVESTIGACION Y DESARROLLO SL
Spain
Net EU contribution
€ 0,00
Address
C/ Severo Ochoa Numero 2 Parque Tecnologico De Mad
28760 Tres Cantos Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
JANSSEN PHARMACEUTICA NV
Belgium
Net EU contribution
€ 0,00
Address
Turnhoutseweg 30
2340 Beerse

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Region
Vlaams Gewest Prov. Antwerpen Arr. Turnhout
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
OTSUKA NOVEL PRODUCTS GMBH
Germany
Net EU contribution
€ 0,00
Address
Erika Mann Strasse 21
80636 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
DEUTSCHES ZENTRUM FUR INFEKTIONSFORSCHUNG (DZIF) EV
Germany
Net EU contribution
€ 0,00
Address
Inhoffenstrasse 7
38124 Braunschweig

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Region
Niedersachsen Braunschweig Braunschweig, Kreisfreie Stadt
Activity type
Research Organisations
Other funding
€ 0,00
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany
Net EU contribution
€ 0,00
Address
Geschwister Scholl Platz 1
80539 Muenchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

KLINIKUM DER UNIVERSITAT MUNCHEN
Germany
Net EU contribution
€ 0,00
Address
Marchioninistrasse 15
81377 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 0,00