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Commercial & Research Opportunity for Cysteinyl Leukotriene Signalling in Ocular & CNS Dysfunction, Cancer and Cardiovascular Disease

Deliverables

CRYSTAL3 initiation

Initiation of CRYSTAL3: Kick-off Meeting and Initiation of Secondments

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Publications

Zebrafish patient-derived xenograft models predict lymph node involvement and treatment outcome in non-small cell lung cancer

Author(s): Zaheer Ali, Malin Vildevall, Gabriela Vazquez Rodriguez, Decky Tandiono, Ioannis Vamvakaris, Georgios Evangelou, Georgios Lolas, Konstantinos N. Syrigos, Alberto Villanueva, Michael Wick, Shenga Omar, Anna Erkstam, Julia Schueler, Anna Fahlgren and Lasse D. Jensen
Published in: Journal of Experimental & Clinical Cancer Research, 41, Article number: 58, 2022, ISSN 0392-9078
Publisher: BioMed Central
DOI: 10.1186/s13046-022-02280-x

Discovery and Development of the Quininib Series of Ocular Drugs

Author(s): Niamh Mahon, Kayleigh Slater, Justine O'Brien, Yolanda Alvarez, Alison Reynolds, and Breandán Kennedy
Published in: Journal of Ocular Pharmacology and Therapeutics, 38, 1, 2022, ISSN 1080-7683
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/jop.2021.0074

Evaluation of the Therapeutic Potential of Histone Deacetylase 6 Inhibitors for Primary and Metastatic Uveal Melanoma

Author(s): Husvinee Sundaramurthi, Zoltán Giricz, and Breandán N. Kennedy
Published in: International Journal of Molecular Sciences, Volume 13, Issue 16, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23169378

Affordable and effective optokinetic response methods to assess visual acuity and contrast sensitivity in larval to juvenile zebrafish

Author(s): Alicia Gómez Sánchez, Yolanda Álvarez, Basilio Colligris, Breandán N. Kennedy
Published in: Open Research Europe, 1, 2021, Page(s) 92, ISSN 2732-5121
Publisher: European Commission Open Research Europe
DOI: 10.12688/openreseurope.13923.1

Uveal Melanoma Cell Line Proliferation Is Inhibited by Ricolinostat, a Histone Deacetylase Inhibitor

Author(s): Husvinee Sundaramurthi, Sandra García-Mulero, Valentina Tonelotto , Kayleigh Slater, Simone Marcon, Josep M. Piulats, Ronald WilliamWatson, Desmond J. Tobin, Lasse D. Jensen and Breandán N. Kennedy
Published in: Cancers, 2022 Feb; 14(3): 782, 2022, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14030782

Dawn and dusk peaks of outer segment phagocytosis, and visual cycle function require Rab28

Author(s): Ailís L. Moran; Stephen P. Carter; Joanna J. Kaylor; Zhichun Jiang; Sanne Broekman; Eugene T. Dillon; Alicia Gómez Sánchez; Sajal K. Minhas; Erwin Wijk; Roxana A. Radu; Gabriel H. Travis; Michelle Carey; Oliver E. Blacque; Breandán N. Kennedy
Published in: The Faseb Journal, 1, 2022, ISSN 0892-6638
Publisher: Federation of American Societies for Experimental Biology
DOI: 10.1096/fj.202101897r