Supramolecular Polyamine Gene Vectors for Cancer Therapy

Project Information

SUPRO-GEN

Grant agreement ID: 101008072

DOI 10.3030/101008072

EC signature date 26 October 2020

Start date 1 September 2021

End date 28 February 2026

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 989 000,00

EU contribution € 989 000,00

Coordinated by

ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE
Spain

Deliverables

Websites, patent fillings, videos etc. (1)

Project Website

A project website will be maintained with uptodate information on project results and secondments and links to conferences events and relevant scientific and outreach activities This will be managed and maintained by CIC biomaGUNE

Publications

Peer reviewed articles (6)

Positron emission tomography studies of the biodistribution, translocation, and fate of poly allyl amine-based carriers for siRNA delivery by systemic and intratumoral administration

Author(s): Cristina Simo, Cristian Salvador, Patrizia Andreozzi, Vanessa Gomez-Vallejo, Gabriela Romero, Damien Dupin, Jordi Llop, Sergio E. Moya
Published in: Small, 2023, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202304326

Assembly and recognition mechanisms of glycosylated PEGylated polyallylamine phosphate nanoparticles: A fluorescence correlation spectroscopy and small angle X-ray scattering study

Author(s): Patricia Perez Schmidt, Tanja Luedtke, Paolo Moretti, Paolo Di Gianvincenzo, Marcos Fernandez Leyes, Bruno Espuche, Heinz Amenitsch, Guocheng Wang, Hernan Ritacco, Laura Polito, M. Grazia Ortore, Sergio E. Moya
Published in: Journal of Colloid And Interface Science, Issue 645, 2023, Page(s) 448-457, ISSN 0021-9797
Publisher: Academic Press
DOI: 10.1016/j.jcis.2023.04.136

Self-Assembled Oleic Acid-Modified Polyallylamines for Improved siRNA Transfection Efficiency and Lower Cytotoxicity

Author(s): Cristian Salvador; Patrizia Andreozzi; Gabriela Romero; Iraida Loinaz; Damien Dupin; Sergio E. Moya
Published in: ACS Applied Bio Materials, Issue 6(2), 2023, Page(s) 529-542, ISSN 2576-6422
Publisher: American Chemical Society
DOI: 10.1021/acsabm.2c00845

Block Copolymer-Stabilized Metal–Organic Framework Hybrids Loading Pd Nanoparticles Enable Tumor Remission Through Near-Infrared Photothermal Therapy

Author(s): Shang-Wei Li, Ming-Feng Hsieh, Taehun Hong, Pengwen Chen, Kensuke Osada, Xueying Liu, Ichio Aoki, Jiashing Yu, Kevin C.-W. Wu, Horacio Cabral
Published in: Advanced NanoBiomed Research, 2024, ISSN 2699-9307
Publisher: Wiley
DOI: 10.1002/anbr.202470011

Controlling the biodistribution and clearance of nanomedicines

Author(s): Horacio Cabral, Junjie Li, Kanjiro Miyata, & Kazunori Kataoka
Published in: Nature Reviews Bioengineering, 2024, ISSN 2731-6092
Publisher: Springer Nature
DOI: 10.1038/s44222-023-00138-1

Polymer-Based mRNA Delivery Strategies for Advanced Therapies

Author(s): Wenqian Yang, Lucas Mixich, Eger Boonstra, Horacio Cabral
Published in: Advanced Healthcare Materials, 2023, ISSN 2192-2659
Publisher: World Scientific
DOI: 10.1002/adhm.202202688