Supramolecular Polyamine Gene Vectors for Cancer Therapy

Informazioni relative al progetto

SUPRO-GEN

ID dell’accordo di sovvenzione: 101008072

DOI 10.3030/101008072

Data della firma CE 26 Ottobre 2020

Data di avvio 1 Settembre 2021

Data di completamento 28 Febbraio 2026

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale € 989 000,00

Contributo UE € 989 000,00

Coordinato da

ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE
Spain

Risultati finali

Websites, patent fillings, videos etc. (1)

Project Website

A project website will be maintained with uptodate information on project results and secondments and links to conferences events and relevant scientific and outreach activities This will be managed and maintained by CIC biomaGUNE

Pubblicazioni

Peer reviewed articles (6)

Positron emission tomography studies of the biodistribution, translocation, and fate of poly allyl amine-based carriers for siRNA delivery by systemic and intratumoral administration

Autori: Cristina Simo, Cristian Salvador, Patrizia Andreozzi, Vanessa Gomez-Vallejo, Gabriela Romero, Damien Dupin, Jordi Llop, Sergio E. Moya
Pubblicato in: Small, 2023, ISSN 1613-6810
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202304326

Assembly and recognition mechanisms of glycosylated PEGylated polyallylamine phosphate nanoparticles: A fluorescence correlation spectroscopy and small angle X-ray scattering study

Autori: Patricia Perez Schmidt, Tanja Luedtke, Paolo Moretti, Paolo Di Gianvincenzo, Marcos Fernandez Leyes, Bruno Espuche, Heinz Amenitsch, Guocheng Wang, Hernan Ritacco, Laura Polito, M. Grazia Ortore, Sergio E. Moya
Pubblicato in: Journal of Colloid And Interface Science, Numero 645, 2023, Pagina/e 448-457, ISSN 0021-9797
Editore: Academic Press
DOI: 10.1016/j.jcis.2023.04.136

Self-Assembled Oleic Acid-Modified Polyallylamines for Improved siRNA Transfection Efficiency and Lower Cytotoxicity

Autori: Cristian Salvador; Patrizia Andreozzi; Gabriela Romero; Iraida Loinaz; Damien Dupin; Sergio E. Moya
Pubblicato in: ACS Applied Bio Materials, Numero 6(2), 2023, Pagina/e 529-542, ISSN 2576-6422
Editore: American Chemical Society
DOI: 10.1021/acsabm.2c00845

Block Copolymer-Stabilized Metal–Organic Framework Hybrids Loading Pd Nanoparticles Enable Tumor Remission Through Near-Infrared Photothermal Therapy

Autori: Shang-Wei Li, Ming-Feng Hsieh, Taehun Hong, Pengwen Chen, Kensuke Osada, Xueying Liu, Ichio Aoki, Jiashing Yu, Kevin C.-W. Wu, Horacio Cabral
Pubblicato in: Advanced NanoBiomed Research, 2024, ISSN 2699-9307
Editore: Wiley
DOI: 10.1002/anbr.202470011

Controlling the biodistribution and clearance of nanomedicines

Autori: Horacio Cabral, Junjie Li, Kanjiro Miyata, & Kazunori Kataoka
Pubblicato in: Nature Reviews Bioengineering, 2024, ISSN 2731-6092
Editore: Springer Nature
DOI: 10.1038/s44222-023-00138-1

Polymer-Based mRNA Delivery Strategies for Advanced Therapies

Autori: Wenqian Yang, Lucas Mixich, Eger Boonstra, Horacio Cabral
Pubblicato in: Advanced Healthcare Materials, 2023, ISSN 2192-2659
Editore: World Scientific
DOI: 10.1002/adhm.202202688