Supramolecular Polyamine Gene Vectors for Cancer Therapy

Información del proyecto

SUPRO-GEN

Identificador del acuerdo de subvención: 101008072

DOI 10.3030/101008072

Fecha de la firma de la CE 26 Octubre 2020

Fecha de inicio 1 Septiembre 2021

Fecha de finalización 28 Febrero 2026

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total € 989 000,00

Aportación de la UE € 989 000,00

Coordinado por

ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE
Spain

Resultado final

Websites, patent fillings, videos etc. (1)

Project Website

A project website will be maintained with uptodate information on project results and secondments and links to conferences events and relevant scientific and outreach activities This will be managed and maintained by CIC biomaGUNE

Publicaciones

Peer reviewed articles (6)

Positron emission tomography studies of the biodistribution, translocation, and fate of poly allyl amine-based carriers for siRNA delivery by systemic and intratumoral administration

Autores: Cristina Simo, Cristian Salvador, Patrizia Andreozzi, Vanessa Gomez-Vallejo, Gabriela Romero, Damien Dupin, Jordi Llop, Sergio E. Moya
Publicado en: Small, 2023, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202304326

Assembly and recognition mechanisms of glycosylated PEGylated polyallylamine phosphate nanoparticles: A fluorescence correlation spectroscopy and small angle X-ray scattering study

Autores: Patricia Perez Schmidt, Tanja Luedtke, Paolo Moretti, Paolo Di Gianvincenzo, Marcos Fernandez Leyes, Bruno Espuche, Heinz Amenitsch, Guocheng Wang, Hernan Ritacco, Laura Polito, M. Grazia Ortore, Sergio E. Moya
Publicado en: Journal of Colloid And Interface Science, Edición 645, 2023, Página(s) 448-457, ISSN 0021-9797
Editor: Academic Press
DOI: 10.1016/j.jcis.2023.04.136

Self-Assembled Oleic Acid-Modified Polyallylamines for Improved siRNA Transfection Efficiency and Lower Cytotoxicity

Autores: Cristian Salvador; Patrizia Andreozzi; Gabriela Romero; Iraida Loinaz; Damien Dupin; Sergio E. Moya
Publicado en: ACS Applied Bio Materials, Edición 6(2), 2023, Página(s) 529-542, ISSN 2576-6422
Editor: American Chemical Society
DOI: 10.1021/acsabm.2c00845

Block Copolymer-Stabilized Metal–Organic Framework Hybrids Loading Pd Nanoparticles Enable Tumor Remission Through Near-Infrared Photothermal Therapy

Autores: Shang-Wei Li, Ming-Feng Hsieh, Taehun Hong, Pengwen Chen, Kensuke Osada, Xueying Liu, Ichio Aoki, Jiashing Yu, Kevin C.-W. Wu, Horacio Cabral
Publicado en: Advanced NanoBiomed Research, 2024, ISSN 2699-9307
Editor: Wiley
DOI: 10.1002/anbr.202470011

Controlling the biodistribution and clearance of nanomedicines

Autores: Horacio Cabral, Junjie Li, Kanjiro Miyata, & Kazunori Kataoka
Publicado en: Nature Reviews Bioengineering, 2024, ISSN 2731-6092
Editor: Springer Nature
DOI: 10.1038/s44222-023-00138-1

Polymer-Based mRNA Delivery Strategies for Advanced Therapies

Autores: Wenqian Yang, Lucas Mixich, Eger Boonstra, Horacio Cabral
Publicado en: Advanced Healthcare Materials, 2023, ISSN 2192-2659
Editor: World Scientific
DOI: 10.1002/adhm.202202688