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BRinging Artificial INTelligencE home for a better cAre of amyotrophic lateral sclerosis and multiple SclERosis

Objective

Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS) are chronic diseases characterized by progressive or alternate impairment of neurological functions (motor, sensory, visual, cognitive). Patients have to manage alternated periods in hospital with care at home, experiencing a constant uncertainty regarding the timing of the disease acute phases and facing a considerable psychological and economic burden that also involves their caregivers. Clinicians, on the other hand, need tools able to support them in all the phases of the patient treatment, suggest personalized therapeutic decisions, indicate urgently needed interventions.

Artificial Intelligence is the key to successfully satisfy these needs to: i) better describe disease mechanisms; ii) stratify patients according to their phenotype assessed all over the disease evolution; iii) predict disease progression in a probabilistic, time dependent fashion; iv) investigate the role of the environment; v) suggest interventions that can delay the progression of the disease.

BRAINTEASER will integrate large clinical datasets with novel personal and environmental data collected using low-cost sensors and apps. Software and mobile apps will be designed embracing an agile and user-centred design approach, accounting for the technical, medical, psychological and societal needs of the specific users.

BRAINTEASER will implement a system able to guarantee cybersecurity and data ownership to the patients; will provide quantitative evidence of benefits and effectiveness of using AI in health-care pathways implementing a proof-of-concept of its use in real clinical setting. Procedural requirements that support Software as Medical Device certification will be used involving clinicians and patients stakeholders and producing a set of recommendations for public health authorities. Results will be disseminated accordingly to an open science paradigm under the European Open Science Cloud initiative.

Field of science

  • /medical and health sciences/health sciences/public and environmental health
  • /social sciences/psychology/psychotherapy
  • /natural sciences/computer and information sciences/software
  • /natural sciences/computer and information sciences/artificial intelligence
  • /medical and health sciences/basic medicine/neurology/amyotrophic lateral sclerosis
  • /medical and health sciences/basic medicine/neurology/multiple sclerosis

Call for proposal

H2020-SC1-DTH-2020-1
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSIDAD POLITECNICA DE MADRID
Address
Calle Ramiro De Maeztu 7 Edificio Rectorado
28040 Madrid
Spain
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 680 000

Participants (10)

UNIVERSITA DEGLI STUDI DI PADOVA
Italy
EU contribution
€ 732 250
Address
Via 8 Febbraio 2
35122 Padova
Activity type
Higher or Secondary Education Establishments
FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS
Portugal
EU contribution
€ 439 375
Address
Campo Grande, Edificio C1, Piso 3
1749 016 Lisbon
Activity type
Research Organisations
UNIVERSITA DEGLI STUDI DI TORINO
Italy
EU contribution
€ 651 875
Address
Via Giuseppe Verdi 8
10124 Torino
Activity type
Higher or Secondary Education Establishments
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
Portugal
EU contribution
€ 315 690
Address
Avenida Prof Egas Moniz
1649 028 Lisboa
Activity type
Research Organisations
SERVICIO MADRILENO DE SALUD
Spain
EU contribution
€ 511 250
Address
Plaza Carlos Trias Bertran 7
28020 Madrid
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
FONDAZIONE ISTITUTO NEUROLOGICO NAZIONALE CASIMIRO MONDINO
Italy
EU contribution
€ 686 250
Address
Via Mondino 2
27100 Pavia
Activity type
Research Organisations
PREDUZECE ZA INFORMACIONE TEHNOLOGIJE I ELEKTRONSKO TRGOVANJE BELIT DOO
Serbia
EU contribution
€ 644 375
Address
Trg Nikole Pasica 9
11000 Beograd
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INSILICOTRIALS TECHNOLOGIES SRL
Italy
EU contribution
€ 551 750
Address
Via Flavia 23 1
34148 Trieste
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ECHALLIANCE COMPANY LIMITED BY GUARANTEE
Ireland
EU contribution
€ 478 000
Address
13A Ballyhoy Avenue Raheny
DUBLIN 5 Dublin
Activity type
Other
THE EUROPEAN BRAIN COUNCIL AISBL
Belgium
EU contribution
€ 198 375
Address
Rue D Egmont 11
1000 Bruxelles
Activity type
Other